Medical Journal of the Islamic Republic Of Iran

en Short-term Side Effects of COVID-19 Vaccines (Astrazeneca, Sputnik-V, and Sinopharm) in Health Care Workers: A Cross-Sectional Study in Iran COVID 19 Original Research Original Research <pre style="text-align:justify"> Background: The occurrence of side effects of vaccines plays an important role in their acceptance by people. Therefore, the aim of this study was to evaluate the side effects of COVID-19 vaccines (Sputnik-V, AstraZeneca, and Sinopharm) in Neyshabur health care workers (HCWs).    Methods: A cross-sectional study was performed to evaluate the side effects of COVID-19 vaccines among the HCWs of the Neyshabur University of Medical Sciences from July 31, 2021, to September 6, 2021, by using a self-report checklist. We sent our checklist via an internet link to collect data such as demographic data of participants, previous COVID-19 infection (PCR+), vaccine information and side effects of vaccines. Mean, median and standard deviation were used to determine descriptive statistics and a logistic regression model was also used to determine the relationship between the type of vaccine and its side effects.    Results: 317 participants filled out the checklist; among them 47% (N= 149), 21.14% (N= 67), and 31.86% (N= 101) have been vaccinated with Sputnik-V, AstraZeneca, and Sinopharm, respectively. The percentage of side effects after the first dose was 62.15% (N= 197). The Percentage of local side effects was 76% (N= 241) and systemic side effects were 29.36% (N= 95). The most common side effects in all three vaccines were injection site pain (75.08%, N= 240), muscle pain (62.46%, N=198) and headache (52.05%, N=165). Also, the odds ratio of injection site pain, chill and sweating in those who received the AstraZeneca vaccine was 3.9(95% CI, 1.7-9.3), 3.7 (95% CI, 1.8-7.3), and 3.2 (95% CI, 1.7-63), of those who received the Sputnik V vaccine (p ≤ 0.001).    Conclusion: The most common side effects among our participants were injection site pain, muscle pain, and headache. Most of the post-vaccination side effects are mild to moderate in severity and self-limited. Reported side effects were more common in recipients with AstraZeneca than in those with Sputnik-V and Sinopharm. </pre> COVID -19 Vaccine, Side effects, AstraZeneca, Sputnik-V, Sinopharm 1244 1249 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-7111-2&slc_lang=en&sid=1 Mohsen Azimi-nezhad aziminezhadm1@nums.ac.ir 200319475328460075226 200319475328460075226 No Noncommunicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran Ali Gholami gholamia1@nums.ac.ir 200319475328460075227 200319475328460075227 No Noncommunicable Diseases Research Center, Neyshabur University of Medical Sciences, Neyshabur, Iran Esmat Taghiabadi taghiyabadie1@nums.ac.ir 200319475328460075228 200319475328460075228 No Affairs of Health, Neyshabur University of Medical Sciences, Neyshabur, Iran Hasan Ghodsi ghodsih1@nums.ac.ir 200319475328460075229 200319475328460075229 Yes Department of Nursing and Midwifery, Neyshabur University of Medical Sciences, Neyshabur, Iran