Medical Journal of the Islamic Republic Of Iran

en Early Failure of Arteriovenous Fistula (AVF): The Effect of Diabetes and Hypertension in a Cross-Sectional Study Surgery Surgery Original Research Original Research Background: Identification and control of clinical predictors of arteriovenous (AVF) failure can improve the long-term outcome of hemodialysis patients. The effects of these factors on the outcome of AVF are not still clear. So, we aimed this study to compare the effect of hypertension and diabetes on early failure of AVF.    Methods: In this retrospective study, we evaluated 400 patients with ESRD referred to our clinic for the creation of the first AVF from July 14, 2001, through August 7, 2018. One month after AVF creation, the patients were referred to the clinic for patency control. Demographic characteristics, previous history of diabetes and hypertension, and laboratory data of all patients were recorded preoperatively. Data were entered to SPSS v.24 and Study data were analyzed with chi-square and independent student t-test. Then, early failure of AVF and its relationship with a history of diabetes and hypertension were assessed.    Results: There was no statistically significant relationship between the history of diabetes and early AVF failure risk in ESRD patients (OR, 0.78; 95% CI, 0.25 to 2.43). Furthermore, the history of hypertension was significantly lower in the early failure of AVF group (OR, -2.82; 95% CI, -1.42 to  -5.59). Although, this effect faded when using regression analysis (OR, -2.67; 95% CI, -0.97 to -7.36). There was a higher Body mass index in the non-early failure group (p = 0.041). There was no significant difference in age (p = 0.512), gender (p = 0.091), history of smoking (p = 0.605), treatment with insulin (p = 0.683), oral antidiabetic agents (p = 0.734), duration of diabetes (p = 0.384), and duration of hypertension (p = 0.093).    Conclusion: We reported that the history of diabetes was not higher in the early failure group, while there was a lower risk of AVF failure in patients with a previous history of hypertension.   End-Stage Renal Disease (ESRD), Arteriovenous Failure (AVF), Early Failure, Non-Early Failure, Diabetes, Hypertension, Obesity 679 684 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-1435-10&slc_lang=en&sid=1 Amir Bahrami-Ahmadi bahramia@gmail.com 200319475328460072037 200319475328460072037 No Occupational Medicine Research Center, Iran University of Medical Sciences, Tehran, Iran Morteza Khavanin Zadeh khavaninzadeh.m@iums.ac.ir 200319475328460072038 200319475328460072038 Yes Hasheminejad Kidney Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran Haleh Chehrehgosha hchehrehgosha@gmail.com 200319475328460072039 200319475328460072039 No Hazrat Rasoul Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran Mohsen Abbasi abbasi.m@iums.ac.ir 200319475328460072040 200319475328460072040 No Department of Emergency Medicine, Hasheminejad Kidney Center, Hazrat Rasoul Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran