en General General Original Research Original Research <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><span style="font-style:italic"><b><span style="font-size:9.0pt"><span style="font-style:normal">Background: </span></span></b><span style="font-size:9.0pt"><span style="font-style:normal">Sex determination is one of the most important criteria in cadaver identification so if it determines accurately, half of the population can be statistically excluded. The aim of this study was to determine the sex according to diagnostic factors in a 3D CT scan of the mandible.</span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Methods:</b> In this cross-sectional study, we selected 197 3D CT scans files of mandible available at PACS of hospitals affiliated with the Iran University of Medical Sciences (IUMS). In this study, we measured mandibular or gonial angle (G angle), ramus length, minimum ramus breadth, maximum ramus breadth, coronoid height, mandibular length, bigonial breadth, bicondylar breadth, symphyseal height, symphyseal height to mandibular length ratio, symphyseal height to ramus length ratio, symphyseal height to bicondylar breadth ratio, symphyseal height to bigonial breadth ratio, ramus length to bigonial breadth ratio, ramus length to bicondylar breadth ratio, bigonial breadth to bicondylar breadth ratio and ramus length to mandibular length ratio. The ROC curve was used to evaluate the diagnostic value of each indicator. </span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Results:</b> There was a significant difference between males and females in all indicators except symphyseal height to mandibular length ratio, symphyseal height to bicondylar breadth ratio, symphyseal height to bigonial breadth ratio and bigonial breadth to bicondylar breadth ratio. The highest AUC, sensitivity, specificity and diagnostic accuracy were related to ramus length, symphyseal height to ramus length ratio, bicondylar breadth and ramus length respectively.</span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Conclusion:</b> Mandible bone 3D CT scan indicators could be used alone to determine sex in the Iranian population.</span></span></span></span></span></span></span></span><br> &nbsp; Sex Determination by Skeleton, Mandible, Sensitivity and Specificity, Imaging, Three-Dimensional, Forensic Medicine 1250 1255 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-774-6&slc_lang=en&sid=1 Zahra Ismaili Shahroudi Moqaddam drzahraisma58@gmail.com 200319475328460075230 200319475328460075230 No Department of Forensic Medicine, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran Mahsa Jamshidi drmahsajamshidi@yahoo.com 200319475328460075231 200319475328460075231 No Oral and Maxillofacial Radiologist, Faculty of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran Foroozan Fares for.farsi@gmail.com 200319475328460075232 200319475328460075232 No Department of Forensic Medicine, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran Abbas Aghabiklooei aghabikloo@hotmail.com 200319475328460075233 200319475328460075233 No Department of Forensic Medicine, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran Mohsen Saberi Isfeedvajani msaberi@bmsu.ac.ir 200319475328460075234 200319475328460075234 Yes Medicine, Quran and Hadith Research Center & Department of Community Medicine, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran