en Gynecology & Obstetrics Gynecology & Obstetrics Original Research Original Research In order to assess the efficacy of hysteroscopic endometrial ablation and factors which are important in it's success, a prospective, randomized study was performed in Shiraz university hospitals between Sep. 1995 to Feb. 1998. 50 patients with chief complaints of menorrhagia that were in reproductive age (25- 50 years) and had shown no response to medication and D&C underwent endometrial ablation. Thirty-seven patients received pre-op medication and thirteen patients did not. All patients had undergone pre-operative endometrial sampling that had demonstrated benign histology. Eleven patients had submucosal myomas or pedunculated polyps that were resected at the time of hysteroscopic ablation. The minimum follow-up period was 1 year. Amenorrhea developed in 14% of patients, 50% of patients became hypomenorrheic and 30% eumenorrheic. Menorrhagia did not respond in 3 patients (6%). Hypermenorrhea was detected more commonly in younger patients. Type of endometrium, depth of the uterine cavity, presence of polyp or myoma and receiving pre-op medication were not important and did not affect patient response. Overall, the results of this study clearly indicate that endometrial ablation is a simple, effective and acceptable procedure for the management of intractable menorrhagia. The only factor which was important concerning the efficacy of endometrial ablation was patient age. Abnormal uterine bleeding, Endometrial ablation, Hysteroscopy. 195 198 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-304&slc_lang=en&sid=1 SAEED ALBORZI 20031947532846004328 20031947532846004328 Yes From the Department of Obstetrics and Gynecology, Division of Endoscopy, Shiraz University of Medical Sciences, Shiraz, I.R. Iran. MOHAMMAD E PARSANEZHAD 20031947532846004329 20031947532846004329 No