Medical Journal of the Islamic Republic Of Iran

en Comparison of Dynamic and Static Compliance in Two Ventilation Methods with Tidal Volume of 6 and 10 ml/kg: Randomized Clinical Trial Anesthesia Anesthesia Original Research Original Research Background: Pulmonary compliance is an important lung factor and is affected by tidal volume. In this study, static and dynamic compliance with tidal volumes of 6 and 10 ml/kg have been evaluated in patients undergoing abdominal cancer surgery.    Methods: This randomized clinical trial was conducted on 50 patients who were candidate for abdominal cancer surgery. This study was done in patients aged 20-65 years without chronic diseases. After induction of anesthesia, the first group was ventilated with a tidal volume of 10 ml/kg and 8 breaths/minute, and also the second group was ventilated with a tidal volume of 6 mL/kg and 14 breaths/minute. From the beginning and every 15 minutes, expiratory tidal volume, peak and plateau airway pressure, heart rate and blood pressure were measured for two hours. The data was analyzed with SPSS v.20 and P < 0.05 was meaningful.    Results: There was no significant difference between the two groups for demographic characteristics. There was no significant difference between the two groups in the dynamic and static compliance of the patients during the study. However, the static compliance decreased in the 6 ml/kg group and increased in the 10 ml/kg group, but the difference was not statistically significant (P = 0.32). The peak, plateau pressure and hemodynamic parameters were the same in the two groups.    Conclusion: In general, the static and dynamic compliance was not significantly different in the two groups despite a slight decrease in the 6 ml/kg group and a slight increase in the 10 ml/kg group.   Mechanical ventilation, Tidal volume, Dynamic compliance, Static compliance 503 507 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-8111-1&slc_lang=en&sid=1 Mehryar Taghavi Gilani taghavim@mums.ac.ir 200319475328460089375 200319475328460089375 No Lung Disease Research Center, Department of Anesthesiology, Mashhad University of Medicine Sciences, Mashhad, Iran Alireza Bameshki bameshkia@mums.ac.ir 200319475328460089376 200319475328460089376 No Lung Disease Research Center, Department of Anesthesiology, Mashhad University of Medicine Sciences, Mashhad, Iran Majid Razavi razavim@mums.ac.ir 200319475328460089377 200319475328460089377 Yes Lung Disease Research Center, Department of Anesthesiology, Mashhad University of Medicine Sciences, Mashhad, Iran Ghorbanali Sadeghzadeh sadeghzadehgh1@mums.ac.ir 200319475328460089378 200319475328460089378 No Lung Disease Research Center, Department of Anesthesiology, Mashhad University of Medicine Sciences, Mashhad, Iran