Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1379
8
1
gregorian
2000
11
1
14
3
online
1
fulltext
en
URINARY BLADDER RECONSTRUCTION USING FRESH AND FORMALIN-PRESERVED BOVINE AMNION IN DOGS
Urology and Nephrology
Urology and Nephrology
Original Research
Original Research
The use of bovine amnion in the urinary tract for reconstructive purposes
following ablative surgery in cases of trauma, cancer or infection is now a common
practice in urological surgery.
To evaluate urinary bladder reconstruction with bovine amniotic membrane
(BAM), ten healthy mongrel dogs of either sex weighing 10-40 kg were used. The
animals were randomly divided into two groups of five animals each. A piece of
the cranial wall of the bladder 5 cm in diameter was resected and replaced with
fresh and formalin-preserved BAM respectively. The graft compatibility was evaluated
on the basis of clinical, biochemical ultrasonographical, radiological and
histopathological changes.
Clinically all of the dogs were dull and depressed with blood tinged urine for
the first few post-operative days. The biochemical parameters didn't show any
significant changes in BUN and creatinine. Ultrasonographic findings consisted
of floating masses in the bladder lumen (40%), chronic cystitis (10%), bladder
adhesion with adjacent tissues (90%) and radiological findings were lack of normal
distension of the graft site (100%) and filling defect (30%). No inflammatory
responses and leakage were observed.
The regeneration of uroepithelium, and proliferation of granulation tissue,
infiltration of lymphoid cells, degenerative changes at the junction of the bladder
and graft and heterotopic bone formation were observed. Keeping in view the
compatibility of the fresh and preserved BAM, this study showed that it can act as
a scaffold for repairing urinary bladder defects in dogs.
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http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-318&slc_lang=en&sid=1
J
BAKHTIARI
20031947532846004372
20031947532846004372
Yes
From the Faculty of Veterinary Medicine, Tehran
F
SABERI-AFSHAR
20031947532846004373
20031947532846004373
No
Chamran Universities of Medical Sciences, Tehran
H
NOORBALA
20031947532846004374
20031947532846004374
No
Dept. of Urology, Baghiyatallah University of Medical Sciences, Tehran, l.R. Iran
MJ
GHARAGOZLO
20031947532846004375
20031947532846004375
No
From the Faculty of Veterinary Medicine, Tehran
A
VESHKINI
20031947532846004376
20031947532846004376
No
From the Faculty of Veterinary Medicine, Tehran