Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1379
5
1
gregorian
2000
8
1
14
2
online
1
fulltext
en
DIAGNOSTIC VALUE OF MEAN PEROXIDASE INDEX IN EARLY KAWASAKI DISEASE
Community Medicine
Community Medicine
Original Research
Original Research
The charts of 27 patients with Kawasaki disease (KD) admitted to Nemazee
Hospital in Shiraz from January 1991 to October 1998 were reviewed to identify
the results of mean peroxidase index (MPXI) values, a measure of neutrophil
staining intensity, obtained by the Technicon HI analyzer (Technicon Instruments
Corp., Tarrytown, NY) within the first 10 days of the illness 2 separate groups of
patients were assessed as control subjects: 27 disease control (DC) children with
fever plus one other KD criterion and 27 laboratory control (LC) subjects with
nonfebrile disorders interpreting also as a normal reference population. Compared
with control groups, patients with KD had lower quantities of MPXI
[(Mean±SD, -11.71±5.87 in KD group) vs. (1.53±4.30 p<0.001 in DC group,
and 1.74±6.52,p<0.001 in LC group)]. Depending on the location of the cut-off
point expressed on an interval scale, this test had the ability to be 100% specific
( if MPXI<-6.0) and 100% sensitive ( if MPXI>0).
Considering the low prevalence of hereditary myeloperoxidase (MPO) deficiency
( 1 in 2000), measurement of MPXI, when performed as part of a complete
count on an automated hematology instrument, could be counted as an important
adjunct to clinical evaluation and also according to the low values of MPXI in patients
with KD, it can be included among the acquired causes of MPO deficiency.
Acute phase, Mucocutaneous lymph node syndrome, Myeloperoxidase deficiency.
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http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-325&slc_lang=en&sid=1
N
NAKHAEE
20031947532846004397
20031947532846004397
Yes
From the Department of Community Medicine, Shiraz University of Medical Sciences, Shiraz, IR. Iran.
A
SADEGHI-HASSANABADI
20031947532846004398
20031947532846004398
No
HR
TABATABAEE
20031947532846004399
20031947532846004399
No