en Oncology Oncology case report case report <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><b><span style="font-size:9.0pt"><span style="font-style:normal">Background: </span></span></b><span style="font-size:9.0pt"><span style="font-style:normal">Sarcomas are one of the major groups of rare cancers and account for <1% of cancers worldwide. Ovarian angiosarcomas are rare and probably arise from carcinosarcomas, teratomas, or the rich ovarian vasculature. Here we present a case of ovarian angiosarcoma.</span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Case:</b> A 35-year-old Iranian woman presented with a 6-month history of vague abdominal pain and a previous history of dermoid cyst. A pelvic MRI reported a large solid and cystic pelvic mass of ovarian origin. She underwent a left oophorectomy. The final pathologist&#39;s conclusion was malignant germ cell tumor including teratoma with malignant transformation in favor of transformation to angiosarcoma. The patient underwent total abdominal hysterectomy and right salpingo-oophorectomy and left salpingectomy. Surgical specimen revealed no malignancy including germ cell tumor, sarcoma or angiosarcoma</span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><b><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; Conclusion:</span></span></b><span style="font-size:9.0pt"><span style="font-style:normal"> Dermoid cyst or mature cystic teratoma is the most common solid type tumor and the most common ovarian tumor occurring at a young age. Angiosarcomas of the ovary, like most other ovarian tumors, are discovered in late stages. There is no standard therapy for angiosarcoma of the ovary. In a review of previous cases, some have observed patients especially in the early stages while others have used adjuvant chemotherapy in the non-metastatic setting, basically doxorubicin-based.</span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal"></span></span></span></span></span></span></span></span><br> &nbsp; Angiosarcoma, Ovary, Dermoid Cyst 1197 1200 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-8226-1&slc_lang=en&sid=1 Monire Mirzaei moniremirzaee00@gmail.com 200319475328460087715 200319475328460087715 No Clinical Research Developmental Center, Qom University of Medical Sciences, Qom, Iran Abbas Eshraghi aeshraqi@muq.ac.ir 200319475328460087716 200319475328460087716 Yes Clinical Research Developmental Center, Qom University of Medical Sciences, Qom, Iran Mahdiieh Ghoddoosi mghodosi12@yahoo.com 200319475328460087717 200319475328460087717 No Department of Pathology, Qom University of Medical Sciences, Qom, Iran Maedehalsadat Fatemi Mrsfatemi@yahoo.com 200319475328460087718 200319475328460087718 No Cancer Research Center, Babol University of Medical Sciences, Babol, Iran Azhar Eshraghi Azhar_eshraghi@yahoo.com 200319475328460087719 200319475328460087719 No Qom University of Medical Sciences, Qom, Iran Zohreh Azad zohreh.azad89@yahoo.com 200319475328460087720 200319475328460087720 No Qom University of Medical Sciences, Qom, Iran Danial Fazilat-panah drfazilatpanah@gmail.com 200319475328460087721 200319475328460087721 No Cancer Research Center, Babol University of Medical Sciences, Babol, Iran Yavar Rajabzadeh yavarrz@gmail.com 200319475328460087722 200319475328460087722 No Cancer Research Center, Babol University of Medical Sciences, Babol, Iran