Medical Journal of the Islamic Republic Of Iran

en Investigation of Factors Affecting Clinical Outcome of Peritoneal Dialysis Patients Urology and Nephrology Urology and Nephrology Original Research Original Research Background: End-stage kidney disease (ESKD) is a global issue. Although the use of kidney replacement therapy measures has improved outcomes for patients with ESKD, the mortality rate remains significant. Identifying modifiable factors that affect patient outcomes can help improve their survival. The aim of this study was to investigate the factors affecting the clinical outcome of peritoneal dialysis patients.    Methods: This prospective cohort study was conducted between 2018 and 2021. Participants: Patients aged between 18 and 75 years with a history of peritoneal dialysis (PD) for at least six months were included. Demographic data, kt/v ratio, medical history, serum levels of albumin, creatinine, triglycerides, total cholesterol, calcium, phosphorus, parathyroid hormone, hemoglobin, and ferritin were recorded before starting PD and during the follow-up period, along with clinical outcomes. To describe the data, the central index of mean, frequency, and relative frequency was used, and for analytical statistics, Chi-square test, analysis of variance, and Kruskal-Wallis were used.    Results: A total of 64 patients with a mean age of 51.78 ± 15.31 years were included. Of these, 27 (42.18%) had a history of diabetes mellitus, and 38 (59.37%) had a history of hypertension (HTN). 48 (75%) patients survived until the end of the study, while 47 (73.4%) participants experienced peritonitis. Our findings indicate that variables such as sex, marital status, weight, history of HTN, and serum levels of hemoglobin and ferritin significantly affect outcomes.    Conclusion: We found that factors including sex, marriage, normal weight, HTN, normal hemoglobin, and ferritin can lead to better survival in PD patients. Recurrent peritonitis was the most crucial cause of PD to HD shifts. Peritoneal Dialysis, Survival, End-stage kidney disease 230 234 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-8331-1&slc_lang=en&sid=1 Najmeh Shamspour n.shamspour@kmu.ac.ir 200319475328460088908 200319475328460088908 Yes Clinical Research Development Unit, Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran Maryam Eslami maryam244.eslami@gmail.com 200319475328460088909 200319475328460088909 No Student Research Committee, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran Jalal Azmandian J.Azmandian@kmu.ac.ir 200319475328460088910 200319475328460088910 No Physiology Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran Behnam Dalfardi b.dalfardi@kmu.ac.ir 200319475328460088911 200319475328460088911 No 4. Endocrinology and Metabolism Research Center, Institute of Basic and Clinical Physiology Science, Kerman University of Medical Sciences, Kerman, Iran Azam Dehghani a.dehghani63@yahoo.com 200319475328460088912 200319475328460088912 No Clinical Research Development Unit, Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran