Medical Journal of the Islamic Republic Of Iran

en Association of Obesity, Sarcopenia, and Functional Mobility with Risk of Fall: A Cross-Sectional Study from Ardakan Cohort Study on Aging (ACSA) Orthopedic Orthopedic Original Research Original Research Background: Falls are considered one of the leading causes of accidental deaths and nonfatal accidental injuries in older adults. Previous research indicates a 1-in-5 yearly fall incidence among Iranian older adults. To examine specific risk factors within this population, our study aimed to evaluate fall risk factors such as obesity, sarcopenia, functional mobility, and activities of daily living (ADL) scores.    Methods: This cross-sectional study used data from the first wave of the Ardakan Cohort Study on Aging (ACSA), involving participants ˃50 years who lived in Ardakan, Iran. The primary outcome was fall history in the past 12 months. The main biomechanical variables included body mass index (BMI), muscle strength, gait speed, static balance, and mobility-assisting devices. Sarcopenia was assessed based on the ratio of hand grip strength to BMI. Multiple logistic regressions assessed associations by odds ratio (OR) and 95% confidence interval.    Results: The final analysis included 4983 participants, 994 of whom reported at least 1 fall. Participants had a mean age of 62.21 ± 4.47 years (50-86 years), with a 48% male distribution. The results of multivariable logistic regression indicated that obesity (OR, 1.02 [95% CI, 0.70- 1.47]; P = 0.910), waist-to-hip ratio (OR, 1.02 [95% CI, 0.74-1.40]; P = 0.903), hand grip strength (OR, 1.20 [95% CI, 0.87-1.66]; P = 0.255), and sarcopenia (OR, 1.11 [95% CI, 0.82- 1.51]; P = 0.474) did not have significant associations with falls. However, impaired standing balance test (OR: 1.64 [95% CI, 1.09-2.47]; P =  0.017) and dependency on ADL (OR, 1.94 [95% CI, 1.05-3.56]; P =  0.032) increased falling.    Conclusion: Impaired balance tests and dependency on ADL increase the risk of falls in older adults. However, obesity indicators, sarcopenia, and gait speed were not associated with the risk of falls.   Obesity, Sarcopenia, Accidental falls, Orthogeriatrics 816 823 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-8377-2&slc_lang=en&sid=1 Ahmad Delbari Ahmad_1128@yahoo.com 200319475328460089593 200319475328460089593 No Iranian Research Center on Aging, Department of Aging, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Amirali Azimi azimi.amirali96@gmail.com 200319475328460089594 200319475328460089594 No Iranian Research Center on Aging, Department of Aging, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Azin Pakmehr azin.pakmehr@gmail.com 200319475328460089595 200319475328460089595 No Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran Mohammad Saatchi m.saatchi65@gmail.com 200319475328460089596 200319475328460089596 No Department of Biostatistics and Epidemiology, University of Social Welfare and Rehabilitation Science, Tehran, Iran Mohammad Bidkhori bidkhori.mohammad93@gmail.com 200319475328460089597 200319475328460089597 No Iranian Research Center on Aging, Department of Aging, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Fatemeh-sadat Tabatabaei Fatimast1995@gmail.com 200319475328460089598 200319475328460089598 No Iranian Research Center on Aging, Department of Aging, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Vahid Rashedi راشدی vahidrashedi@yahoo.com 200319475328460089599 200319475328460089599 No Iranian Research Center on Aging, Department of Aging, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Elham Hooshmand هوشمند El.hooshmand@uswr.ac.ir 200319475328460089600 200319475328460089600 Yes Iranian Research Center on Aging, Department of Aging, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran