en Preventive Medicine & Community Health Preventive Medicine & Community Health Original Research Original Research <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><span style="font-style:italic"><b><span style="font-size:9.0pt"><span style="font-style:normal">Background: </span></span></b><span style="font-size:9.0pt"><span style="font-style:normal">Spinal muscular atrophy is an inherited neurodegenerative disorder that typically leads to severe physical disability. The present study aimed to determine the subjective evaluation of this disorder screening and analyze its influencing factors in Iran.</span></span><span lang="AR-SA" style="font-size:9.0pt">&lrm;</span>&nbsp;&nbsp;</span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Methods:</b> A cross-sectional study was performed using data from the second survey of women either pregnant or planning to become pregnant in Tehran, the capital of Iran, in 2022. The dependent variable was the willingness to pay for this disease screening test. The independent variables included sociodemographic, economic, and health characteristics, the history of this disease or other diseases of the person and family, and knowledge about this disease in the included population. Logistic regression was utilized to identify independent variables associated with the dependent variable, and the results were reported as unadjusted and adjusted odds ratios and P values with 95% CIs. A questionnaire was used as a research tool, and STATA 17 software was used for data analysis. The monetary value of spinal muscular atrophy (SMA) screening was calculated by estimating willingness to pay using the congenital valuation method. </span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Results:</b> In total, 578 women were included. About 64.85% of respondents had a willingness to pay for SMA screening as the dependent variable, with a mean of $526. University education (</span></span><span style="font-size:9.0pt">P</span><span style="font-size:9.0pt"><span style="font-style:normal"> = 0.009) and pregnancy experience (</span></span><span style="font-size:9.0pt">P</span><span style="font-size:9.0pt"><span style="font-style:normal"> = 0.021) were associated with the dependent variable.</span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span new="" roman="" style="font-family:" times=""><span style="font-style:italic"><b><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; Conclusion:</span></span></b><span style="font-size:9.0pt"><span style="font-style:normal"> Iranian women expressed their willingness to undergo screening tests, but due to financial constraints, they expected the government and nongovernmental organizations to bear most of the cost. </span></span></span></span></span></span></span></span><br> &nbsp; Spinal Muscular Atrophy, Willingness to Pay, Carrier Screening, Contingent Valuation ‎Method, ‎Logistic Regression Model 352 359 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-8203-1&slc_lang=en&sid=1 Majid Khosravi khosravi.m1@gmail.com 200319475328460089272 200319475328460089272 No Department of Health Economics, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran Aziz Rezapour rezapour.a@iums.ac.ir 200319475328460089273 200319475328460089273 Yes Health Management and Economics Research Center, Health ManagementResearch Institute, Iran University of Medical Sciences, Tehran, Iran Najmeh Moradi najme.moradi@gmail.com 200319475328460089274 200319475328460089274 No Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom Setare Nassiri Zeidi setare_n99@yahoo.com 200319475328460089275 200319475328460089275 No Department of Obstetrics and Gynecology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran Namamali Azadi azadi.n@iums.ac.ir 200319475328460089276 200319475328460089276 No Department of Biostatistics, School of Public Health, Iran University of Medical Sciences, Tehran, Iran