Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1378
5
1
gregorian
1999
8
1
13
2
online
1
fulltext
en
THE EFFECT OF ANTIHYPERTENSIVE DRUGS IN THE SUPPRESSION OF ATHEROSCLEROSIS
Artificial intelligence
Original Research
Original Research
The present investigation was undertaken to evaluate the effect of
antihypertensive drugs on aortic atherogenesis in hypercholesterolemic rabbits. In
enalapril and nifedipine treated rabbits aortic atherosclerotic plaque involvement
was significantly decreased (p<0. Oland p<O. 05, respectively) as compared to the
control group. However, in hydrochlorothiazide treated rabbits aortic atherogenesis
was marginally inhibited, whereas in clonidine treated rabbits it was similar to the
control group. These results suggest that the inhibition of atherogenesis in
enalapril and nifedipine treated rabbits is independent of hypercholesterolemia
and may be relevant in the selection of antihypertensive drugs, provided their
protective effect can be demonstrated in future clinical trials as well.
Antihypertensive drugs, Atherosclerosis, Hypercholesterolemia
93
96
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-399&slc_lang=en&sid=1
HASSAN
FALLAH HUSAINI
20031947532846004623
20031947532846004623
Yes
From the Institute of Medicinal Plants and Natural Products, Tehran, I.R.lran
MANSURI
SABERAH
20031947532846004624
20031947532846004624
No
B.J. Medical College, Ahmedabad 6, India