en Gynecology & Obstetrics Gynecology & Obstetrics Original Research Original Research <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><b><span style="font-size:11.0pt"><span style="font-family:&quot;Calibri&quot;,sans-serif"><span style="color:#31849b"><span style="font-style:normal"></span></span></span></span></b></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><b>&nbsp;&nbsp;</b><b><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp; Background: </span></span></b><span style="font-size:9.0pt"><span style="font-style:normal">Considering low-quality evidence regarding the impact of laparoscopic surgery on in vitro fertilization (IVF) success rates in women with endometriosis, our research aimed to evaluate IVF success rates and their influential factors in women with endometriosis-related infertility who underwent laparoscopic surgery.</span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Methods:</b> In a retrospective cohort study, we included women aged 15 to 40 years diagnosed with endometriosis-related infertility who underwent laparoscopic surgery in a university hospital. Women with severe male factor infertility, adenomyosis, uterine myomas, premature ovarian insufficiency, incomplete information, or inaccessible data from infertility centers were excluded. Data were collected from the Endometriosis Data Registry approved by the Iran University of Medical Sciences under code number 1400-2-65-21233, including age, body mass index, infertility duration, endometriosis severity, and Anti-M&uuml;llerian hormone levels before IVF. IVF success was considered by an embryonic heartbeat identification during an ultrasound exam, that is, a clinical pregnancy. Independent sample t test, Mann-Whitney, and chi-square tests were applied for single-variable analysis, and logistic regression was used for multivariable analysis.</span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Results:</b> Of 55 eligible patients, IVF was successful in 23 (41.81%). The mean age of participants was 34.98 years, with a standard deviation of 5.93 years. Endometriomas were observed in 42 (76%) of the participants; unilateral endometriomas were more common than bilateral (25 [45.5%] vs 17 [30.9%]). No significant differences were identified between the IVF-positive and IVF-negative groups regarding clinical and demographic characteristics. </span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Conclusion:</b> Laparoscopic surgery in women with deep infiltrating endometriosis enhances IVF success and increases pregnancy rate.</span></span></span></span></span></span></span></span><br> &nbsp; Endometriosis, Laparoscopy, Assisted Reproductive Technique, In Vitro Fertilization, Infertility 486 491 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-9272-1&slc_lang=en&sid=1 Abolfazl Mehdizadehkashi amehdizadehkashi@yahoo.com 200319475328460091356 200319475328460091356 No Endometriosis Research Center, Iran University of Medical Sciences, Tehran, Iran Shahla Chaichian shchaichian@gmail.com 200319475328460091357 200319475328460091357 No 2. Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran Roya Derakhshan "Dr. Roya Derakhshan" 200319475328460091358 200319475328460091358 No Endometriosis Research Center, Iran University of Medical Sciences, Tehran, Iran Farahnaz Farzaneh f.farzaneh2019@gmail.com 200319475328460091359 200319475328460091359 No Department of Obstetrics and Gynecology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran Azam Govahi azam.govahi@yahoo.com 200319475328460091360 200319475328460091360 No Endometriosis Research Center, Iran University of Medical Sciences, Tehran, Iran Azar Mohammadzadeh mohammadzadehazar@gmail.com 200319475328460091361 200319475328460091361 No Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran Banafsheh Nikfar banafsheh.nikfar@gmail.com 200319475328460091362 200319475328460091362 No Pars Advanced and Minimally Invasive Medical Manners Research Center, Pars Hospital, Iran University of Medical Sciences, Tehran, Iran Yasaman Kabir Anaraki kabiryasaman@gmail.com 200319475328460091363 200319475328460091363 Yes Department of Obstetrics and Gynecology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran