Medical Journal of the Islamic Republic Of Iran

en Clinical Presentation and Chest CT Abnormalities in Adults with Mycoplasma Pneumoniae CAP During the 2023-2024 Outbreak Infectious Disease Infectious Disease In Brief     Background: The recent increase in the incidence of Mycoplasma pneumoniae has renewed interest in this pathogen and the range of clinical manifestations it can cause. This study aims to describe clinical and CT features of community-acquired pneumonia caused by Mycoplasma pneumoniae (MCAP).    Methods: We prospectively collected data on hospitalized adults with MCAP during the 2023-2024 outbreak. Clinical manifestation, laboratory data, and radiological abnormalities were evaluated. The data were analyzed using descriptive statistics.     Results: A total of 40 patients were enrolled, with a median age of 35 (22; 45) years, and 24 (60%) were male. The primary symptoms were cough (40 patients, 100%), fever (38 patients, 95%), and general weakness (35 patients, 87.5%). Laboratory tests revealed a moderate increase in С-reactive protein levels, with a median of 77.1 (37.3;123.0) mg/L. The most common radiological findings were ground‑glass opacity in 36 patients (90%) and bronchial wall thickening in 33 patients (82.5%). No patients required admission to the intensive care unit, and there were no deaths during the hospital stay.    Conclusion: In our study, MCAP predominantly affected young and middle-aged adults with a favorable course and prognosis. The current outbreak requires attention in terms of using optimal diagnostic and treatment methods. Mycoplasma pneumoniae, Community-acquired pneumonia, Chest computed tomography 1144 1147 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-9515-1&slc_lang=en&sid=1 Olga Kupriushina Olga.kupriushina@yandex.ru 200319475328460094239 200319475328460094239 No I.M. Sechenov First Moscow State Medical University, Hospital Therapy Department №2, Moscow, Russia Rifat Aynetdinov aynetdinov_r_m@staff.sechenov.ru 200319475328460094240 0009-0001-4145-1292 No I.M. Sechenov First Moscow State Medical University, Pulmonology Department, Moscow, Russia Svetlana Rachina Svetlana.Ratchina@antibiotic.ru 200319475328460094241 200319475328460094241 No I.M. Sechenov First Moscow State Medical University, Hospital Therapy Department №2, Moscow, Russia Daria Strelkova dashastrelkova@gmail.com 200319475328460094242 200319475328460094242 Yes I.M. Sechenov First Moscow State Medical University, Hospital Therapy Department №2, Moscow, Russia Sergey Avdeev avdeev_s_n@staff.sechenov.ru 200319475328460094243 200319475328460094243 No I.M. Sechenov First Moscow State Medical University, Pulmonology Department, Moscow, Russia Irina Trofimenko tin11@mail.ru 200319475328460094244 200319475328460094244 No Irkutsk State Medical Academy of Postgraduate Education – Branch Campus of the Russian Medical Academy of Continuous Professional Education, Clinical Allergology and Pulmonology Department, Irkutsk, Russia Vladimir Antonov Ant-vn@yandex.ru 200319475328460094245 200319475328460094245 No Federal State Budgetary Educational Institution of Higher Education “South-Ural State Medical University” of the Ministry of Healthcare of the Russian Federation, Therapy Department, Chelyabinsk, Russia Tatiana Yudanova yudanovata@gmail.com 200319475328460094246 0009-0007-1803-8778 No Smolensk Regional Clinical Hospital, Pulmonology Department, Smolensk, Russia Maria Agibalova agmarni@mail.ru 200319475328460094247 0009-0009-7126-5827 No State budgetary health care institution of Arkhangelsk region «Kotlas central city hospital named after St. Luke (V.F. Voyno-Yasenetskiy), Clinical Pharmacology Department, Kotlas, Russia Olga Ivanova terapia@list.ru 200319475328460094248 200319475328460094248 No Branch No. 4 of the Federal State Institution «1586 Military Clinical Hospital» of the Ministry of Defense of the Russian Federation, Pulmonology Department, Smolensk, Russia Zamira Merzhoeva merzhoeva_z_m@staff.sechenov.ru 200319475328460094249 200319475328460094249 No I.M. Sechenov First Moscow State Medical University, Pulmonology Department, Moscow, Russia Anastasia Yasneva anastasiia.iasnieva@mail.ru 200319475328460094250 200319475328460094250 No I.M. Sechenov First Moscow State Medical University, Hospital Therapy Department №2, Moscow, Russia Elena Volosovtsova ess.1999.07@gmail.com 200319475328460094251 0009-0006-7515-3724 No I.M. Sechenov First Moscow State Medical University, Pulmonology Department, Moscow, Russia Svetlana Yatsyshina svetlana.yatsyshina@pcr.ms 200319475328460094252 200319475328460094252 No Central Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Laboratory of Molecular Diagnostics and Epidemiology of Respiratory Tract Infections, Moscow, Russia Marina Tikhonova tihonova@cmd.su 200319475328460094253 0009-0005-0359-3694 No Central Research Institute for Epidemiology of the Federal Service for Supervision of Consumer Rights Protection and Human Welfare, Laboratory of Molecular Diagnostics and Epidemiology of Respiratory Tract Infections, Moscow, Russia Inna Edelstein Inna.Edelstein@antibiotic.ru 200319475328460094254 200319475328460094254 No Smolensk State Medical University, Institute of Antimicrobial Chemotherapy, Smolensk, Russia Oksana Barashko o.barashko@inbox.ru 200319475328460094255 0009-0004-7766-3256 No Smolensk Regional Clinical Hospital, Pulmonology Department, Smolensk, Russia Olga Tigunceva otigunceva@mail.ru 200319475328460094256 0009-0000-2238-4963 No Irkutsk Order “Badge of Honor” Regional Clinical Hospital, Pulmonology Department, Irkutsk, Russia