en General General Original Research Original Research <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><b>&nbsp;&nbsp;</b><b><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp; Background: </span></span></b><span style="font-size:9.0pt"><span style="font-style:normal">The prevalence of gastrointestinal symptom in the world (5-11%), Western (10-40%), and Asian countries (5%-30%) is almost half of the entire population. Medical students are a vulnerable group of the general public who have prolonged study hours, reduced hours of sleep and free activities, as well as the many exams that must be passed to be able to graduate. Medical students have higher stress level than other students. This study aims to quantitative validity and reliability test of the Indonesian version-GSRS questionnaire and assess sleep quality, stress level, and diet with gastrointestinal symptom among medical students. </span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Methods:</b> The research study design is a cross-sectional study and simple random sampling. Other questionnaires used in this research are PSQI to assess sleep quality, MSSQ to assess stress level, and FFQ to assess diet. The data analysed using Kendall&#39;s tau_b bivariate correlation test at SPSS version 24 software. </span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Results:</b> The result from 136 respondents, quantitative validation with item validity method and reliability tests is valid (</span></span><span style="font-size:9.0pt">P</span><span style="font-size:9.0pt"><span style="font-style:normal"><0.05) and reliable (&alpha;=0.900) for the Indonesian version-GSRS questionnaire. The majority of respondents had mild severity of gastrointestinal symptom (N=111; 81.6%), bad sleep quality (N=116; 85.3%), moderate stress level (N=56; 41.2%), and excessive dietary pattern (N=65; 47.8%). </span></span></span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="text-justify:kashida"><span style="text-kashida:0%"><span style="text-autospace:none"><span style="font-family:&quot;Times New Roman&quot;,serif"><span style="font-style:italic"><span style="font-size:9.0pt"><span style="font-style:normal">&nbsp;&nbsp; <b>Conclusion: </b>The Indonesian version-GSRS questionnaire can be used as an initial measurement tool for symptoms of gastrointestinal disorders in the Indonesian community. There is a relationship between gastrointestinal symptoms and sleep quality, stress level, and diet in medical students.</span></span></span></span></span></span></span></span><br> <br> <span style="font-size:10pt"><span style="line-height:200%"><span new="" roman="" style="font-family:" times=""><span lang="EN-GB" style="font-size:12.0pt"><span style="line-height:200%"></span></span></span></span></span> Medical Students, Gastrointestinal Symptom, Sleep Quality, Stress Level, Diet 1283 1292 http://mjiri.iums.ac.ir/browse.php?a_code=A-10-9648-1&slc_lang=en&sid=1 Eka Arum Cahyaning Putri eka-arum-cp@fk.unair.ac.id 200319475328460094729 200319475328460094729 Yes Department of Physiology and Medical Biochemistry, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia Muhammad Naufal Razzan Maghribi muhammad.naufal.razzan-2022@fk.unair.ac.id 200319475328460094730 0009-0006-2919-7021 No Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia Muhammad Nabiel Firdausi m.nabiel.firdausi-2022@fk.unair.ac.id 200319475328460094731 0009-0008-5931-4326 No Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia Emilda Puteri Aulia emilda.puteri.aulia-2022@fk.unair.ac.id 200319475328460094732 0009-0003-3641-5179 No Medical Program, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia Hayuris Kinandita Setiawan hayuris-k-s@fk.unair.ac.id 200319475328460094733 200319475328460094733 No Department of Physiology and Medical Biochemistry, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia Rimbun Rimbun rimbun@fk.unair.ac.id 200319475328460094734 200319475328460094734 No Department of Anatomy, Histology, and Pharmacology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia Raden Argarini raden-a@fk.unair.ac.id 200319475328460094735 200319475328460094735 No Department of Physiology and Medical Biochemistry, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia Annisa Zahra Mufida a.zahra.mufida@fk.unair.ac.id 200319475328460094736 200319475328460094736 No Department of Internal Medicine, Universitas Airlangga Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia Amie Vidyani amie.vidyani@fk.unair.ac.id 200319475328460094737 200319475328460094737 No Department of Internal Medicine, Universitas Airlangga Hospital, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia Misbakhul Munir misbakhulmunir@fk.unair.ac.id 200319475328460094738 200319475328460094738 No 1. Department of Physiology and Medical Biochemistry, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia