Medical Journal of the Islamic Republic Of Iran
مجله پزشکی جمهوری اسلامی ایران
Med J Islam Repub Iran
Medical Sciences
http://mjiri.iums.ac.ir
2
journal2
1016-1430
2251-6840
8
10.18869/mjiri
14
8888
13
en
jalali
1377
11
1
gregorian
1999
2
1
12
4
online
1
fulltext
en
DISCRIMINATION OF HEPATOCELLULAR CARCINOMA FROM CIRRHOTIC NODULES BY AgNOR STAIN
Pathology
Pathology
Original Research
Original Research
Discrimination of regenerative cirrhotic nodules of the liver (CN) from
hepatocellular carcinoma (HCC) is sometimes difficult. We examined the utility of
AgNOR staining in this context. Fifteen cases of HCC and 25 cases of CN were
stained by AgNOR method and the mean AgNOR number for one hundred nuclei in
each case was determined. There was a significant difference between the mean
AgNOR counts in CN (6.63±4.00) and HCC (11.36±2.88) (p<0.0005).
Discriminant analysis showed that all HCC cases and over 90% of CN could be
correctly distinguished by this method. It seems that AgNOR staining is an accurate
and readily available tool for differentiating CN from HCC.
Cirrhosis, Cirrhotic nodule, Hepatocellular carcinoma, AgNOR.
329
331
http://mjiri.iums.ac.ir/browse.php?a_code=A-10-298-434&slc_lang=en&sid=1
ALI
ZARE MEHRJARDI
20031947532846004722
20031947532846004722
Yes
From the Department of Pathology, Kerman University of Medical Sciences, Kerman, I.R. Iran
MEHDI
MASSOUMIAN
20031947532846004723
20031947532846004723
No