Volume 2, Issue 1 (5-1988)                   Med J Islam Repub Iran 1988 | Back to browse issues page

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SHAFIEE A, VOSOOGHI M, TABATABAII M, SAVABI F, Vlahov R, Tarpanov. V, et al . LONG-ACTING CONTRACEPTIVE AGENTS: TESTOSTERONE ESTERS OF CYCLOALKYLCARBOXYLIC ACIDS. Med J Islam Repub Iran 1988; 2 (1) :47-49
URL: http://mjiri.iums.ac.ir/article-1-1284-en.html
LONG-ACTING CONTRACEPTIVE AGENTS: TESTOSTERONE ESTERS OF CYCLOALKYLCARBOXYLIC ACIDS
A SHAFIEE , M VOSOOGHI , M TABATABAII , F SAVABI , R Vlahov , V Tarpanov. , B Milkenkov, , M Boshkova-Ljapova , J Vlahov , G Snatzke
From the Department of Chemistry. College of Pharmacy, Tehran University of Medical Sciences. Tehran, Islamic Republic of Iran
Abstract:   (4175 Views)
The synthesis of twenty five esters of testosterone (17β -hydroxyandrost- 4-en-3-one) is described. All esters are derivatives of cycloalkycarboxylic acids. Some of the esters possess α- , β -and/or & - substitution in the ester side-chain. The work was undertaken in order to evaluate long-acting male antifertility effect of such esters. Most of the compounds, especially compound No.1, were found to be active. Compound No.1 is presently under clinical studies.
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Type of Study: Original Research | Subject: Biological Sciences
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