Volume 28, Issue 1 (1-2014)                   Med J Islam Repub Iran 2014 | Back to browse issues page

XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Heidari B, Khashayar P, Rezai Homami M, Pajouhi A, Soltani A, Larijani B. Dual-energy X-ray absorptiometry diagnostic discordance between Z-scores and T-scores in a young Iranian population. Med J Islam Repub Iran. 2014; 28 (1) :1016-1022
URL: http://mjiri.iums.ac.ir/article-1-2617-en.html
Endocrinology & Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. , soltania@tums.ac.ir
Abstract:   (3156 Views)

  Background: Dual-energy X-ray Absorptiometry (DXA) is considered the gold standard for non-invasive measurement of bone mass. T-scores and Z-scores are used to present the results of bone mass. The present study was designed to evaluate the discordance between T-scores and Z-scores calculated at a same level and its relation with age, gender and body mass index (BMI) in a representative sample of normal population.

  Methods :This cross-sectional study was conducted as a part of a comprehensive survey, Iranian Multicenter Osteoporosis Study (IMOS), designed to assess bone health among healthy adults. Each individual underwent both L1–L4 antero-posterior lumbar spine and hip DXA scan. The difference between the T- and Z-scores measured at each of the four skeletal sites was then calculated.

  Results : A -1.21 to 1.21 point difference was noted in the Z- and T- scores measured at each site. While the difference between the T- and Z-scores was less than 0.5 SD in most of the cases, the difference was higher than 1 SD in about 5% of the subjects.

  Conclusion : Standardization of Z-score definition and calculation techniques as well as developing an ethnicity-matched reference population is needed to improve the reliability of DXA-generated Z-scores.

 

Full-Text [PDF 1853 kb]   (1032 Downloads)    
Type of Study: Original Research | Subject: Endocrinology

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author