Volume 33, Issue 1 (2-2019)                   Med J Islam Repub Iran 2019 | Back to browse issues page


XML Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Malekzadeh M, Asadi M, Abbasi-Rad S, Abolghasemi J, Hamidi Z, Talebi M, et al . MDCT-QCT, QUS, and DXA in healthy adults: An intermodality comparison. Med J Islam Repub Iran 2019; 33 (1) :960-964
URL: http://mjiri.iums.ac.ir/article-1-5996-en.html
Finetech in Medicine Research Center, & Medical Physics Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran , shiran.m@iums.ac.ir
Abstract:   (1958 Views)
Background: Cortical deceleration is the main reason for bone loss at peripheral sites. It was suggested that when peripheral bones were assessed for osteoporosis, management and therapy can be administered early. The main aim of this study was to assess the relationships between the central and peripheral measurements at different skeleton bone sites (spine, femur, forearm, tibia, and calcaneus) with available modalities: DXA, QUS, and MDCT-QCT.
   Methods: The volunteers recruited in this study did not have any history or evidence of metabolic bone disease.  Blood test and DXA measurements were used as inclusion criteria to select 40 healthy participants. The selected volunteers underwent 3 imaging modalities: QCT, DXA, and QUS. DXA-based measurements were made on 3 sites, including spine, femur, and forearm. QCT and QUS measurements were done for distal of tibia and calcaneus bones, respectively.  The extracted parameters from the 3 modalities were analyzed using a bivariate (Pearson) correlation (r) in statistical software.
   Results: The results showed moderate to good correlations between spongy bones in central and peripheral sites from all the modalities. However, there was no correlation between MDCT measures and central bone values. According to correlations between different peripheral sits, aBMD of 33% radius and trabecular vBMD in 38% distal tibia showed weak but significant relationship between peripheral bones (r=-0.342, p=0.044).
   Conclusion: The findings demonstrated how bones in central and peripheral sites were correlated. Multimodality imaging was used in this group of healthy volunteers. Also, it was found that QCT-based MDCT needs more optimization and requires further investigations. 
 
Full-Text [PDF 446 kb]   (467 Downloads)    
Type of Study: Original Research | Subject: Medical Physics

Add your comments about this article : Your username or Email:
CAPTCHA

Send email to the article author


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.