Volume 18, Number 1 (5-2004)                   Med J Islam Repub Iran 2004 | Back to browse issues page


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MOAYERI H, BAHREMAND S. PREVALENCE OF CELIAC DISEASE IN CHILDREN AND ADOLESCENTS WITH TYPE I DIABETES MELLITUS. Med J Islam Repub Iran. 2004; 18 (1) :39-43
URL: http://mjiri.iums.ac.ir/article-1-650-en.html

From the Pediatrics Department. Imam Khomeini Hospital. Faculty of Medicine. Tehran University of Medical Sciences. Tehran. Iran. , H. Moayeri @ radsa net.
Abstract:   (2067 Views)
The association of celiac disease and type I diabetes mellitus has been known for some time. This study was undertaken to investigate the prevalence of celiac disease (CD) in diabetic children and adolescents. Eighty-seven patients (44 females, 43 males) aged 2- 18 years, with type I diabetes participated in this study. A group of 87 healthy unrelated girls and boys matched for age and gender served as controls. They were screened for the presence of celiac disease related marker [IgA - endomysial antibody (EMA)] and patients who were EMA positive further investigated with intestinal biopsy. Among diabetic patients a 3.4% prevalence of celiac disease was observed, a value significantly higher than that found among healthy controls. Girls were more frequently EMA positive than boys. Intestinal biopsies of all 3 patients with positive EMA showed a histologic picture confirming the diagnosis of CD. Diabetics with CD were significantly younger, had an earlier onset of diabetes, had a lower height and weight standard deviation score and poorer glycemic control compared with diabetics without CD (p
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