Volume 13, Issue 1 (5-1999)                   Med J Islam Repub Iran 1999 | Back to browse issues page

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ESMAILI DUKI M, KHATAMI G, NAJAFI M, KHODADAD A. CLINICAL MANIFESTATIONS AND DIAGNOSIS OF CELIAC DISEASE IN CHILDREN. Med J Islam Repub Iran 1999; 13 (1) :33-36
URL: http://mjiri.iums.ac.ir/article-1-969-en.html
CLINICAL MANIFESTATIONS AND DIAGNOSIS OF CELIAC DISEASE IN CHILDREN
MR ESMAILI DUKI , GR KHATAMI , M NAJAFI , A KHODADAD
From the Department of Pediatrics, Gastroenterology Division, Children's Medical Center, TehrOl1 University of Medical Sciences, Tehran, Islamic Republic of Iran.
Abstract:   (4757 Views)
Celiac disease (CD) is defined as a permanent intolerance to gluten with clinical manifestations and abnormal small intestinal mucosa. A case series study was performed to obtain information about clinical manifestations, age of presentation and diagnosis of CD. For this purpose, hospital records of patients who were admitted to the gastrointestinal ward in the Children's Medical Center from 1986 to 1996 with suspected diagnosis of CD and discharged with such a diagnosis were reviewed. Thirty-five patients (17 male, 18 female) with diagnostic criteria for CD were selected and followed, The average age of onset was 3.07 years but mean age of diagnosis (the first small intestinal biopsy) was 7.7 years. The most common symptom was chronic diarrhea. The interval between initial symptoms and diagnosis was surprisingly long. During this period these subjects had multiple medical visits at different hospitals. With recognition of this treatable disorder and by available diagnostic procedures and obtaining small intestinal biopsy specimens, we can reduce the mentioned interval and diagnose this entity earlier in Iranian children.
Keywords: Celiac disease. Gluten, Children
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Type of Study: Original Research | Subject: Pediatric
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