Medical Journal of The Islamic Republic of Iran (MJIRI)
Iran University of Medical Sciences
Wed, Sep 3, 2025
[Archive]
Volume 39, Issue 1 (1-2025)
Med J Islam Repub Iran 2025 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Hamzehnava E, Zamani F, Ajdarkosh H, Khoonsari M, Faraji A, Sobhrakhshankhah E, et al . Evaluation of Advanced Endoscopic Stents for Pancreatic Pseudocyst Drainage: A 2-Year Study. Med J Islam Repub Iran 2025; 39 (1) :896-904
URL: http://mjiri.iums.ac.ir/article-1-9691-en.html
URL: http://mjiri.iums.ac.ir/article-1-9691-en.html
Esmaeil Hamzehnava 
, Farhad Zamani , Hossein Ajdarkosh , Mahmoodreza Khoonsari , Amirhossein Faraji , Elham Sobhrakhshankhah , Masoumeh Nejatifar , Shahaboddin Dolatkhah , Mohadese Sedighi Pashaki , Fahimeh Safarnezhad Tameshkel , Roghayeh Sahraie , Mehdi Nikkhah
, Farhad Zamani , Hossein Ajdarkosh , Mahmoodreza Khoonsari , Amirhossein Faraji , Elham Sobhrakhshankhah , Masoumeh Nejatifar , Shahaboddin Dolatkhah , Mohadese Sedighi Pashaki , Fahimeh Safarnezhad Tameshkel , Roghayeh Sahraie , Mehdi Nikkhah
Gastrointestinal and Liver Diseases Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, Iran , nikkhah.m@iums.ac.ir
Abstract: (34 Views)
Background: Endoscopic ultrasound (EUS)-guided drainage using lumen-apposing metal stents (LAMS) is the first line choice for treatment of pancreatic fluid collections (PFCs). This study evaluated the technical success, clinical success, and adverse events (AE) associated with the Hot AXIOS electrocautery-enhanced LAMS for pancreatic pseudocysts (PPs).
Methods: This retrospective cohort study included 45 patients with PPs undergoing Hot AXIOS stent placement between 2019 and 2021. Clinical and technical success were assessed. AEs were graded based on severity and timing. Survival analysis and the Kaplan-Meier curve were used in the study.
Results: Technical success was achieved in 97.78% (44/45) cases and clinical success in 95.56% (43/45). Patients with a previous history of PP intervention were significantly more likely to experience moderate to severe AE (P = 0.009). Removal time of stent was significantly longer in patients with moderate or severe AE (median 70 vs 34.5 days, P = 0.005). Transition of PP to walled-off necrosis was associated with moderate or severe AE in comparison with mild or no AE (P < 0.001).
Conclusion: Hot AXIOS stents demonstrated high clinical and technical success rates for PP drainage. Patients with a history of prior interventions for PPs were at significantly higher risk of AE. Closer monitoring is recommended in patients with delayed removal. Future studies should incorporate a multicenter design and control groups with standardized success rates and AE definitions.
Methods: This retrospective cohort study included 45 patients with PPs undergoing Hot AXIOS stent placement between 2019 and 2021. Clinical and technical success were assessed. AEs were graded based on severity and timing. Survival analysis and the Kaplan-Meier curve were used in the study.
Results: Technical success was achieved in 97.78% (44/45) cases and clinical success in 95.56% (43/45). Patients with a previous history of PP intervention were significantly more likely to experience moderate to severe AE (P = 0.009). Removal time of stent was significantly longer in patients with moderate or severe AE (median 70 vs 34.5 days, P = 0.005). Transition of PP to walled-off necrosis was associated with moderate or severe AE in comparison with mild or no AE (P < 0.001).
Conclusion: Hot AXIOS stents demonstrated high clinical and technical success rates for PP drainage. Patients with a history of prior interventions for PPs were at significantly higher risk of AE. Closer monitoring is recommended in patients with delayed removal. Future studies should incorporate a multicenter design and control groups with standardized success rates and AE definitions.
Type of Study: Original Research |
Subject:
Gastroenterology
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
