KHALILI M A, VAHIDI S, AFLATOUNIAN A, KARIMZADEH M A, AMIR-ARJMAND H. INTRACYTOPLASMIC SPERM INJECTION FOR THE TRE ATMENT OF MALE FA CTOR INFERTILITY-THE FIRST PRELIMINA RY REPORT FROM IRAN. Med J Islam Repub Iran 1997; 11 (3) :181-185
URL:
http://mjiri.iums.ac.ir/article-1-1088-en.html
From the Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Bou-Ali Avenue, Yazd,l.R. Iran.
Abstract: (4208 Views)
The latest micromanipulative technique, intracytoplasmic sperm injection
(ICSI), has been very successful in cases of severe male factor infertility. The main
objective of this study is to report the results of our fIrst experience with ICSI in
cases of male factor infertility, as well as patients who had failed their previous
cycles with conventional in vitro fertilization (IVF). Normal fertilization occurred
in 30.9% of oocytes retrieved from 99 patients. Embryo transfer was done for
67.7% of the patients, and a total of 12 (12.12%) clinical pregnancies were
achieved. The success rate was noticeably lower in patients greater than 35 years
old, and in patients with severely abnormal sperm parameters (e.g.,
oligoasthenoteratozoospermia). This study suggests that ICSI is a method of
choice to treat couples with severe male factor infertility. Patients' age, as well as
sperm parameters, can affect the success rate of infertility treatment with ICSI.