Volume 10, Issue 1 (5-1996)                   Med J Islam Repub Iran 1996 | Back to browse issues page

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KARAMIZADEH Z, AMIRHAKIMI G. EXPERIENCE WITH 115 PATIENTS WITH CONGENITAL A DREN AL HYPERPLASIA AND EVALUATION OF GROWTH PATTERNS IN 24 PATIENTS WITH THE SALT-LOSING TYPE. Med J Islam Repub Iran 1996; 10 (1) :17-20
URL: http://mjiri.iums.ac.ir/article-1-1212-en.html
From the Department of Pediatrics, Shiraz University of Medical Sciences, Shiraz, Islamic Republic of Iran.
Abstract:   (4247 Views)
In this study the data on 115 cases of congenital adrenal hyperplasia (CAH) who were followed in the Pediatric Endocrine Clinic at Nemazee Hospital, Shiraz will be reported. Among these cases 51 were male and 64 female. The most common type of CAH in these patients was the salt-losing type of 21 -hydroxylase deficiency (85 .2%). ll-hydroxylase deficiency was present in 13.04% of patients. There was only one case with 20 ,22 -desmolase deficiency and one also with 3-betahydroxysteroid dehydrogenase deficiency. Presenting complaints were ambiguous genitalia, vomiting, failure to thrive, precocious puberty and hypertension. The analysis of data on 24 patients with the salt-losing type of21-hydroxylase deficiency who were followed for at least 2 years showed that these patients suffered from abnormal growth patterns. Growth failure was maximal during the first year of life.
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Type of Study: Original Research | Subject: Pediatric

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