Volume 2, Issue 4 (2-1989)                   Med J Islam Repub Iran 1989 | Back to browse issues page

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DJALILIAN M, FARHADI M, NAZEM F. PENDRED'S SYNDROME REVISITED. Med J Islam Repub Iran 1989; 2 (4) :305-311
URL: http://mjiri.iums.ac.ir/article-1-1240-en.html
PENDRED'S SYNDROME REVISITED
M DJALILIAN , M FARHADI , F NAZEM
From the Department of Otorhinolaryngology, Iran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Abstract:   (4958 Views)
Pendred's syndrome is defined as a triad of congenital perceptive hearing loss, goiter, and abnormal perchlorate test. Three brothers with Pendred's syndrome [P.S.] are reported. The oldest brother has hearing loss (he has been deaf and mute since childhood) and has a large goiter. A thyroid scan revealed euthyroid multinodular goiter and a perchlorate test was performed, and reported abnormal. His brother had the same manifestations but with less severity and after subtotal thyroidectomy, the pathology report revealed follicular carcinoma. The youngest brother had hearing loss since childhood but a normal sized thyroid. We report three patients and compare the frequency of their symptoms with that reported in the literature.
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Type of Study: case report | Subject: Otorhinolaryngology
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