From the Dept. of Physiology. Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz.lslamic Republic of Iran
Abstract: (4025 Views)
Effects of acute systemic hypoxia on the cardiovascular system (CYS) and
respiration of spontaneously breathing cats were studied in two conditions. 1):
Hypoxic air (6-8% 02 in N2) was given to the animal to induce systemic hypoxia for
20 minutes. Hyperventilation at this condition lowered arterial C02 tension (PaC02
hypocapnia). 2): In the second run, induction of hypocapnia was prevented by adding
3-5% C02 to hypoxic air. Comparison of the results of this study indicated that
hypoxia, independent of the presence of hypocapnia, caused a significant increase in
respiratory rate, aortic flow and arterial blood pressure. However, in the presence of
hypocapnia, the increased respiratory rate was 10% less and a general arterial
vasconstriction was observed.