Volume 27, Issue 1 (Published 28 February 2013)                   Med J Islam Repub Iran 2013 | Back to browse issues page

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Dorgalaleh A, Shahid Shahzad M, Younesi M R, Sanei Moghaddam E, Mahmoodi M, Varmaghani B, et al . Evaluation of liver and kidney function in favism patients. Med J Islam Repub Iran 2013; 27 (1) :17-22
URL: http://mjiri.iums.ac.ir/article-1-1691-en.html
Evaluation of liver and kidney function in favism patients
Akbar Dorgalaleh , Muhammad Shahid Shahzad , Mohammad Reza Younesi , Esmaeil Sanei Moghaddam , Mohammad Mahmoodi , Bijan Varmaghani , Zahra Kashani Khatib , Shaban Alizadeh
Hematology Department, Allied Medical School, Tehran University of Medical Sciences, Tehran, Iran. , alizadehs@sina.tums.ac.ir
Abstract:   (4805 Views)
 Backgrounds: G6PD deficiency is the most common enzymopathy of red blood cells. The clinical symptoms of favism are jaundice, hematuria and haemolytic anaemia that seem to affect liver and kidney in long term. Thus we evaluate kidney and liver function of favism patients in an endemic area of the disease with a high rate of fava beans cultivation.

 

Methods: This study was performed on favism patients and healthy controls referring to Iranshahr central hospital. Liver and kidney function tests were performed.

 Results: The results showed a statistically significant difference between these two groups (p <0.05) for liver function tests, (AST, ALT and ALP), but not for renal tests (BUN and creatinine) (p >0.05).

 

Conclusion: Due to abnormalities were seen in the liver function tests of these patients, we suggest that these tests be regularly performed for favism patients who are constantly exposed to oxidant agents.

 
Keywords: G6PD, Favism, Liver, Kidney.
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Type of Study: Original Research | Subject: Hematology
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