Volume 28, Issue 1 (1-2014)                   Med J Islam Repub Iran 2014 | Back to browse issues page

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Roushan N, Zali F, Abtahi H, Asadi M, Taslimi R, Aletaha N. Reflux esophagitis in war-related sulfur mustard lung disease. Med J Islam Repub Iran 2014; 28 (1) :188-191
URL: http://mjiri.iums.ac.ir/article-1-2291-en.html
Reflux esophagitis in war-related sulfur mustard lung disease
Nader Roushan , Fateme Zali , Hamidreza Abtahi , Mehrnaz Asadi , Reza Taslimi , Najme Aletaha
Department of Internal Medicine, Division of Gastroenterology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran. , nroshan@tums.ac.ir
Abstract:   (3841 Views)

  Background: Sulfur mustard (SM) has acute and chronic effects on skin and mucosal surfaces. The aim of the study was to evaluate the frequency of esophagitis in a historical cohort of veterans who had been exposed to SM in Iran-Iraq war nearly 25 years ago.

  Methods : One hundred two veterans with dyspepsia and/or heartburn underwent esophago-gastro-duodenoscopy. Of them, 52 cases had been exposed to SM and had chronic mustard lung disease. Controls included 50 veterans without SM exposure. Esophagitis was defined according to standard criteria.

  Results : 81.6% of cases and 70.6% of controls had heart burn and/or regurgitation (p= 0.224). Esophagitis was seen in 40% of cases and 26.5% of controls (p= 0.155).

  Conclusion : Based on our findings, SM exposure seems not to be associated with increased esophagitis.

  

Keywords: Sulfur mustard, Esophagitis, Gastroesophageal reflux.
Full-Text [PDF 212 kb]   (1644 Downloads)    
Type of Study: Original Research | Subject: Gastroenterology
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