Here, we present a case of a 78-year-old man that underwent gastrointestinal endoscopy because of one- month
history of dysphagia to liquids and solid foods with accompanying weight loss. On endoscopy, there was distal
esophageal stenosis. Multiple biopsies were obtained. Histologic examination of the samples revealed normal
tissue. The stenosis was treated by dilatation and abdomino pelvic computed tomography scanning was performed
to search for an underlying malignant lesion that showed a mass adjacent to distal esophagus. We did
endosonography- guided fine needle aspiration of the mass. It was a squamous cell carcinoma (SCC). Malignancy
is a challenging diagnosis in patients with dysphagia and near normal endoscopy. To our knowledge,
there are a few reports of SCC to cause it.
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