PARSANEZHAD M, VAFAEI H, LAHSAEE M, ALBORZI S, SCHMIDT E. A COMPARATIV E , DOUBLE -BLIND, RANDOMIZE D, PLACEBO- CONTROLLED TRIAL OF INTRAPERITONEAL ADMINISTRATION OF BUPIVACAINE AND LIDOCAINE FOR PAIN CONTROL AFTER DIAGNOSTIC LAPARO SCOPY. Med J Islam Repub Iran 2003; 17 (2) :107-111
URL:
http://mjiri.iums.ac.ir/article-1-699-en.html
From the Department of Obstetrics & Gynecology, Shiraz University of Medical Sciences , parsame@sums.ac.ir
Abstract: (5211 Views)
The purpose of this study was to compare the effect of intraperitoneal
bupivacaine and lidocaine administration on pain reduction after diagnostic
laparoscopy. In this randomized, double blind, placebo controlled study, diagnostic
laparoscopy was done for one-hundred and ninety-six infertile women with
unexplained infertility. Patients were randomized to 4 groups (A, B,C, and D). At
the end of the procedure, 30 mL of 0.125% bupivacaine, 30 mL of 5% lidocaine
and 30 mL of normal saline was instilled in the pelvic cavity and 15 mL of the
same solution over the diaphragmatic vault in group A, B and C, respectively.
Group D received no intraperitoneal substance. The verbal pain scale questionnaire
was used for assessment of postoperative pain.
In conclusion, when instilled intraperitoneally after diagnostic laparoscopy,
bupivacaine significantly decreases postoperative pain for a long period. It also
reduces the rate of analgesic needed, increases the rate at which patients were
discharged 2 hours after surgery, and decreases hospital stay. It is highly effective
compared to lidocaine and placebo.