From the Department of Anesthesiology, Sina Hospital, Tehran University of Medical Sciences, Tehran, I.R.Iran
Abstract: (4015 Views)
The present study was designed to assess the efficacy of fentanyl and
pancuronium combined with dilute lidocaine solution for axillary block. Onehundred
adult patients undergoing upper limb surgery were randomly allocated to
receive either 0.6 mL/kg of 1 % lidocaine (6 mg/kg) or 0.6 mLlkg of 0.5% lidocaine
(3 mg/kg) with 1 µg/kg of fentanyl and 0.5 mg of pancuronium. The onset of
sensory and motor blocks was significantly shorter in the 1 % lidocaine group
(p<0.05). However no differences in analgesia or motor blockade were found
between the two groups, during the later 20 min. after block. The procedure was
considered successful in 100% of patients without the necessity of supplementary
medication, and no adverse effect were observed in the two groups, and the time
of the first request for analgesia was not significantly different between the two
groups. We conclude that the addition of fentanyl plus pancuronium to the lidocaine
solution, with an unknown mechanism of effect on major nerve block, reduces
the dose of the local anesthetic and possibly systemic toxicity.
Type of Study:
Original Research |
Subject:
Anesthesia