Medical Journal of The Islamic Republic of Iran (MJIRI)
Iran University of Medical Sciences
Wed, Nov 27, 2024
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Volume 15, Issue 2 (8-2001)
Med J Islam Repub Iran 2001 |
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MAHMOUDIAN SHOOSHTARI M, WILSON A, WATKIN P, FINERTY S, MORGAN A. THE IN VITRO GROWTH PROPERTIES OF CELL LINES FROM EPSTEIN-BARR VIRUS-INDUCED TAMARIN TUMORS AND TAMARIN B CELLS TR ANSFORMED BY EPSTEIN BARR VIRUS. Med J Islam Repub Iran 2001; 15 (2) :89-92
URL: http://mjiri.iums.ac.ir/article-1-809-en.html
URL: http://mjiri.iums.ac.ir/article-1-809-en.html
From the Iranian Blood Transfusion Organization, Tehran, I.R. Iran
Abstract: (4147 Views)
EBV-carrying human cell lines, depending on whether the cells are derived
from Burkitt's lymphoma (BL) tumor biopsies or transformed by EBV in vitro,
have different growth properties in vitro. In contrast, there are no clear differences
between tamarin tumor lines and tamarin LCLs in vitro. Both types of tamarin
cell lines could grow in agarose and formed colonies unlike human LCLs, although
with a lower cloning efficiency than BL lines. The growth patterns of the
tamarin tumor lines resemble more those of human LCLs than human BL lines,
although the observation that tamarin LCLs can grow in agarose whereas human
LCLs cannot may be significant. If it is accepted for arguments sake that Raji BL
cells are representative of human EBV BL tumor cells, then both tamarin LCLs
and tumor lines are more tumorigenic as judged by the single criterion of growth
in agarose
Type of Study: Original Research: Basic Science in Medicine |
Subject:
Heart
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