Volume 14, Issue 3 (11-2000)                   Med J Islam Repub Iran 2000 | Back to browse issues page

XML Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
GHADERI A, SHOSHTARI J, FARJADIAN S, YOUSEFI-POUR G, AMIRZARGAR A. HLA-DRBI ALLELE FREQUENCY IN MYAS THENIA GRAVIS PATIENTS FROM SOUTHERN IRAN. Med J Islam Repub Iran 2000; 14 (3) :223-225
URL: http://mjiri.iums.ac.ir/article-1-857-en.html
HLA-DRBI ALLELE FREQUENCY IN MYAS THENIA GRAVIS PATIENTS FROM SOUTHERN IRAN
A GHADERI , J SHOSHTARI , S FARJADIAN , GH YOUSEFI-POUR , A AMIRZARGAR
From the Departments of Immunology and Neurology, Unit of Internal Medicine, Medical School, Shiraz University of Medical Sciences, Shiraz, I.R. Iran , immunol@sums.ac.ir
Abstract:   (4104 Views)
HLA-DRB1 allele frequencies of 28 myasthenia gravis (MG) patients, residents of southern Iranian provinces, were studied using PCR-SSP method. The control group consisted of 100 healthy individuals of the same ethnic group. The allele HLA-DRB1 * 16 (RR= 2.04, p= 0.028) was found to be significantly increased in MG patients compared to the control group, whereas HLADRB1 * 15(RR= 0.17 p= 0.043) and HLA-DRB1 *07 (p= 0.036) were found to be significantly increased in the control group compared to the patients, and seem to be negatively associated with the disease.
Keywords: Myasthenia gravis, HLA-DRBl, PCR-SSP
Full-Text [PDF 244 kb]   (1735 Downloads)    
Type of Study: Original Research | Subject: Immunology
Add your comments about this article : Your username or Email:
CAPTCHA
Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.