Medical Journal of The Islamic Republic of Iran (MJIRI)

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Malnutrition-related diabetes mellitus (MRDM) is a major form of secondary diabetes, restricted to tropical developing countries. We studied 200 cases of diabetes mellitus aged 6-18 years in Fars Province to find the prevalence of MRDM. There were 14 cases who had clinical and laboratory findings compatible with MRDM. The mean age at presentation was 8.6±3 years, with a male to female ratio of3:4. Moderate to severe malnutrition was noted in 92.9% of the subjects. Insulin requirement was more than 2 U/kg/day in 85.7% of the patients. 57.2 % of the patients were from poor socioeconomical class (income less than 200,000 rials per month and a family size>7 members). Recurrent abdominal pain, painless bilateral parotid swelling, lower extremity edema, ascites, retinopathy and renal failure were observed in 50%, 21.4%,35.7%, 14.3%, and 7.1 % of the cases, respectively. An abnormal pancreatic ultrasonography was noted in 35.7% of the subjects. Ketoacidosis, regardless of other findings , was seen in 42 % of the patients. Malabsorption, chronic diarrhea and pancreatic calcifications were not observed. Finally, the prevalence of malnutrition-related diabetes mellitus was 7% in the diabetic population of Fars Province.

Keywords: Malnutrition-related diabetes mellitus

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