From the Department of Internal Medicine, Kashan University of Medical Sciences, Kashan, Islamic Republic of Iran.
Abstract: (4668 Views)
Tracheobronchopathia osteochondroplastica (TO) is a rare and usually benign
disorder affecting the trachea and occasionally the bronchi.
A case of TO was diagnosed in a 61 year old male farmer presenting with
pulmonary infections and prolonged productive cough. A bronchoscopy revealed
multiple nodular excrescences aong the anterolateral wall of the trachea and main
bronchi. CT scans showed moderate narrowing and distortion of the trachea.
Biopsies revealed squamous metaplasia, and calcification and ossification in the
epithelial surface. The literature on the subject is reviewed here. The severity of
TO ranges from no symptoms to severe dyspnea, hemoptysis or pneumonitis. The
etiology and pathogenesis is unknown. Treatment is seldom necessary. Awareness
of the condition as a differential diagnosis to neoplasms is important to avoid
unnecessary surgery or chemotherapy.