Showing 21 results for Dehghani
Gholam A. Dehghani, A Bahaedini,
Volume 8, Issue 1 (5-1994)
Abstract
Effects of acute systemic hypoxia on the cardiovascular system (CYS) and
respiration of spontaneously breathing cats were studied in two conditions. 1):
Hypoxic air (6-8% 02 in N2) was given to the animal to induce systemic hypoxia for
20 minutes. Hyperventilation at this condition lowered arterial C02 tension (PaC02
hypocapnia). 2): In the second run, induction of hypocapnia was prevented by adding
3-5% C02 to hypoxic air. Comparison of the results of this study indicated that
hypoxia, independent of the presence of hypocapnia, caused a significant increase in
respiratory rate, aortic flow and arterial blood pressure. However, in the presence of
hypocapnia, the increased respiratory rate was 10% less and a general arterial
vasconstriction was observed.
Ga Dehghani, H Najafipour,
Volume 9, Issue 3 (10-1995)
Abstract
Metabolic acidosis and severe hypotension are the main causes of irreversibility
during hemorrhagic shock. The influence of these two factors on durations of shock
period and survival time were studied in four groups of anesthetized cats. In group
I the animals were made hypotensive by reducing mean arterial blood pressure (Pa)
to 45 mmHg with concurrent metabolic acidosis. [n group II the same level of
hypotension was produced, along with an intravenous infusion of 12% sodium
bicarbonate solution (0.25 ml/kg/min.) thus metabolic acidosis was prevented and
arterial blood pH (pHa) was kept within its normal range. In group III the Pa was kept
at 50 mmHg in the presence of metabolic acidosis, and in group IV, the Pa was kept
at 50 mmHg (the same as group Ill) but acidosis was prevented. Durations of shock
period and survival times of all groups were compared. The results of this study show
that I) preventing metabolic acidosis increased survival time by 400%, 2) keeping
the Pa at 50 mmHg increased survival time by 800 percent, and 3) prevention of
metabolic acidosis at a Pa of 50 mmHg still augmented survival time by more than
250 percent. We therefore conclude that control of pHa and prevention of severe
hypotension may increase survival rates in patients suffering from hemorrhage.
G.a Dehghani, A Khoshbaten,
Volume 9, Issue 4 (2-1996)
Abstract
Effects of acute hypercapnia on the cardiovascular system (CYS) were studied
in the anesthetized cat. After surgery the animal was exposed to a gas mixture of
12% CO2 and 25% O2 in nitrogen, and hypercapnia with low levels of arterial pH
(pHa) was produced for 20 minutes. In the second run the same level of
hypercapnia was induced by ventilating the same cat from the above gas mixture
but pHa was kept normal by a slow and continuous infusion of 1HAM (0.5 mM/
kg/min). Results of this study showed that hypercapnia increased aortic flow and
induced peripheral vasodilation. Hypercapnia produced tachycardia in the
presence of arterial acidosis whereas in its absence this response reversed to
bradycardia. Hypercapnia increased mean arterial blood pressure (Pa) by 20%
during low pHa, whereas this increase was only 10% in the absence of arterial
acidosis. Therefore, it is concluded that hypercapnia in conjunction with arterial
acidosis has a much stronger stimulatory influence on the CYS via different
arterial chemoreceptors.
Gholam A. Dehghani,
Volume 12, Issue 4 (2-1999)
Abstract
The purpose of this study was to investigate the potential responses of the
cardiovascular system and regional blood flow to hypoxic hypoxia (BB) and to
carbon monoxide (CO)-induced hypoxia (COH). Ten anesthetized cats were studied
under two nonnoxic (control: CONT) and two hypoxic conditions. Four types of
radioactive micro spheres were used to measure regional blood flow during CONT
and two hypoxic conditions. During CONT the animal was ventilated with 22% 02'
5% CO2 and N2 (room air). HH was induced by ventilating the cat for 15 min with
6-8% O2, and COH by adding 0.1 % CO to room air and reducing blood oxygen
content to the same level as HH. Cardiac output and contractility significantly
increased (p<0.05) during HH and COH but this increase was more pronounced
during HB. There was a 22% increase in mean arterial blood pressure (Pa) without
a significant change in total peripheral resistance (TPR) during HH. On the other
hand, despite a 47% increase in cardiac output during COH, there was a 29%
reduction in Pa which was due to peripheral vasodilation (TPR diminished by 45%).
Analysis of regional blood flow (mL/min per 100g) showed that each organ acted
differently. Coronary blood flow (80±7 CONT) increased during HH (678±153)
and COH (584±1 06). Cerebral blood flow (30±4 CONT) was augmented during HH
(86±7) and COH (124±14). Gracilis muscle, hepatic artery, renal, and small and large
intestine blood flow did not change significantly during systemic hypoxia (p>O.05).
Gastric blood flow (14±2 CONT) only increased during HH (22±4) but splenic
blood flow (119±2 CONT) decreased with both HH (40±9) and COH (37±9).
Regional blood flow of other segments measured showed a mixed response to HH
and COH. In conclusion, it seems that: 1) systemic hypoxia would stimulate the heart
to increase its output to maintain Pa and overcome the increased demand of some
organs, and 2) the different responses of regional vascular beds to HH and COH may
be due to various sensitivities of each organ to arterial blood oxygen tension and
autonomic neuro-hormonal controls that have originated from stimulations of aortic
and carotid chemoreceptors.
Hossein Moravej, Seyed Mohsen Dehghani,
Volume 27, Issue 4 (Published 8 October 2013)
Abstract
Background:
Training of pediatric residents is a dynamic process which should be changed as
the nature and epidemiology of pediatric diseases change. In this study, we
compared the training program of the pediatric residents with the disorders of
the pediatric patients who had referred to pediatric offices.
Methods:
The study was conducted in pediatric offices in Shiraz, South of Iran. The main
complaints of all the patients who were referred to these offices in the first
3 days of the four seasons of the year were recorded. Finally, descriptive
statistics was used to determine the frequency of different complaints among
these patients.
Results:
There are 58 Pediatrics offices in Shiraz and 37 offices completed the
questioners (64%). The most frequent complaints of the patients were related to
infections, especially respiratory and gastrointestinal ones. Nutritional and
growth problems were other frequent complaints. Nonetheless, a high number of
the patients were referred due to skin, eye, or ear problems or for check up of
the baby.
Conclusion:
There is an important training–practice problem in the curriculum of pediatric
residents. Thus, we suggest decreasing the periods of inpatient subspecialty
training and increasing the period of outpatient dermatology, ophthalmology,
otolaryngology, and well-baby clinics.
Mehrdad Solati, Elham Ouspid, Saeedeh Hosseini, Nepton Soltani, Mansoor Keshavarz, Mohsen Dehghani,
Volume 28, Issue 1 (1-2014)
Abstract
Background : Magnesium is the second most abundant intracellular cation. It plays an important role in insulin homeostasis and glucose metabolism through multiple enzymatic reactions. With increasing data on magnesium deficiency in diabetic patients and epidemiological studies demonstrating magnesium deficiency as a risk factor for diabetes, it is logical to search for its possible beneficial effects on diabetes control and prevention. We aimed to determine whether oral magnesium supplementation improves metabolic control, lipid profile and blood pressure in patients with type II diabetes.
Methods : Fifty four patients with type II diabetes were included in a randomized double blind placebo-controlled clinical trial.Patients received either placebo or 300 mg elemental magnesium (as magnesium sulfate -MgSo4-) daily, for 3 months. Metabolic control, lipid profile, blood pressure, magnesium status, hepatic enzymes, hemoglobin concentration, and anthropometric indices were determined in the beginning and at the end of the study.
Results: Daily administration of 300 mg elemental magnesium for 3 months, significantly improved fasting blood glucose (183.9±15.43 to 125.8±6.52 vs. 196.5±28.12 to 136.5±7.94, p< 0.0001), 2-hour post prandial glucose (239.1±74.75 to 189.1±60 mg/dl vs. 246.4±97.37 to 247.8±86.74 mg/dl, p< 0.01), lipid profile, blood pressure and hepatic enzymes.
Conclusion: Oral magnesium supplementation with proper dosage has beneficial effects on blood glucose, lipid profile, and blood pressure in patients with type II diabetes.
Mahdi Shahriari, Sezaneh Haghpanah, Javad Dehghani, Javad Dehbozorgian, Peyman Eatemadfar, Asghar Bazrafshan, Mehran Karimi,
Volume 28, Issue 1 (1-2014)
Abstract
Background :Highserum level of cancer antigen 15.3 (CA15.3) has been reported in some malignant and nonmalignant conditions including thalassemia major which could have been resulted from ineffective erythropoiesis. We aimed to evaluate the serum level of CA15.3 in carriers of beta-thalassemia by comparing them with cancer patients and healthy individuals.
Methods : This cross-sectional study was done from February to December 2011 in Southern Iran. Participants consisted of 32 subjects with beta-thalassemia minor, 49 with cancer and 25 healthy individuals. The serum levels of CA15.3 were measured and compared in different groups.
Results : The serum levels of CA 15.3 in all participants were in the normal range (<35 U/mL). Also it did not significantly differ among various groups of the participants (p=0.723). Age was not significantly correlated with the serum level of CA 15.3 (r= 0.039, p=0.702). The most frequent cancer in the group of patients with malignancies was hematologic malignancies (96%) with the highest frequency for acute lymphoblastic leukemia (37 patients). Frequency of thalassemia minor in patients with cancer was 11 (22.4%).
Conclusion: Nocorrelation was found between CA 15.3 serum level with beta-thalssemia minor or with childhood malignancies. Compared to general population, a high proportion of beta-thalssemia minor was observed in patients with cancer in our study. Future prospective studies are needed to evaluate the relationship between cancer and beta-thalassemia minor accurately.
Fatemeh Sari Aslani, Bita Geramizadeh, Amir Reza Dehghanian,
Volume 29, Issue 1 (1-2015)
Abstract
Background: Melanoma causes the greatest morbidity and mortality of all skin cancers. Mucosal melanoma is a rare but highly aggressive neoplasm. According to previous studies the prevalence of KIT mutations in acrallentiginous and mucosal melanomas is relatively low (less than 15–20%), but it can have profound therapeutic implications for localized high risk or metastatic diseases. Our goal was to evaluate c-Kit expression in different types of primary and metastatic melanoma to discriminate potential candidates for targeted therapy.
Methods : We designed a cross-sectional study and selected 50 cases of malignant melanoma (primary, metastatic cutaneous, and mucosal) from the affiliated hospitals of Shiraz University of Medical Sciences in the period of 2008 to 2012. Immunohistochemistry for KIT expression was performed. Multistage sampling method was selected for sampling and chi-square test was used for statistical analysis.
Results : In our study, male to female ratio was 1.77. The male sex was correlated with higher tumor stage (p<0.05). 62% (n=31) of cases showed at least 5% of KIT-positive cells, consist of 18% (n=9) with 5–50%, 16% (n=8) with 51–95%, and 28% (n=14) of cases showed more than 95% of cells expressing KIT. But in 38% (n=19) of cases KIT expression was less than 5% of positive cells. Tumor stage was positively correlated with tumor cell immunoreactivity and intensity (p<0.05). Metastatic melanoma showed lower percentage (43%) of positivity. Intensity of staining and percentage of positive cells were positively correlated (p<0.001).
Conclusion : In primary melanomas, significant KIT expression was found by immunohistochemistry, which may be useful to screen the patients for advising to KIT mutation analysis and targeted therapy.
Hossein Sanaei-Zadeh, Sayed Mahdi Marashi, Rouhullah Dehghani,
Volume 31, Issue 1 (1-2017)
Abstract
Background: Scorpionism is a public health problem in some provinces in Iran. The present study aimed to assess the clinical manifestations of scorpion envenomation in Shiraz and determine a clinical severity grading for Iranian scorpion envenomation in order to suggest a treatment guideline for emergency physicians.
Methods: In this analytic retrospective study, all medical charts of patients with scorpion sting admitted in the adult medical toxicology center in Shiraz during July 2012 to July 2016 were assessed. Data regarding the patient's age, gender, sting site, month of envenomation, time of sting, clinical manifestations, vital signs, presence of blood or hemoglobin in urine analysis, duration of admission, color of scorpion, received treatments, and administration of scorpion antivenin were recorded.
Results: The scorpions in Shiraz and its suburban area were classified into two groups: yellow scorpions (Mesobuthus eupeus, Mesobuthus caucasicus, and Compsobuthus matthiesseni) and Hottentotta scorpions (Hottentotta jayakari and Hottentotta zagrosensis). A total of 126 cases of scorpion stings were assessed. About 59% (n=74) were males. The patients aged 8-63 years (mean age, 33.8±11.5 years). About 38.4% (n=48) of the stings occurred during summer. More than 40% of patients (n=51) referred to the emergency department (ED) at night. Localized pain was the most frequent presenting complaint (76.2%). The most frequent general symptom was nausea (6.3%). The most prevalent envenomation site was the lower extremities followed by upper extremities (43.5% and 41.9%, respectively). Based on the clinical severity grading for Iranian scorpion envenomation, 65, 43, and 18 patients (51.6%, 34.1%, and 14.3%) were classified in the grades I, II, and III, respectively. Eighty-one (73%) patients stayed in the ED from 1 to 6 hours, and 30 (27%) patients stayed for >6 hours for observation. Severe localized pain was more prevalent in stings with Hottentotta scorpions than yellow scorpions (P=0.01). The season of envenomation with Hottentotta scorpions was summer in all cases, but envenomation with yellow scorpions was seen throughout the year. All patients received symptomatic treatment, and five were given scorpion antivenin. No death was reported.
Conclusion: Hottentotta jayakari is recommended to be listed among the medically important scorpions in Iran. Moreover, scorpion-stung patients in geographical regions where Hemiscorpius lepturus and Androctonus crassicauda are not prevalent may be treated in outpatient departments. The presented grading system can be used for treating patients with scorpion envenomation.
Morteza Khavnin Zadeh, Amirhossein Dehghani Esfahani, Alireza Azadeh,
Volume 32, Issue 1 (2-2018)
Abstract
For doing systemic chemotherapy, central venous ports are used to access central veins and internal jugular vein. Installing these devices though can be with complications on the side which cause them function limits. In this text a case is presented in which after installing a complete and intact port, some malfunction was detected in the chemotherapy procedure after several months which leads us to port Malposition which is probably caused by the huge soft tissue of patient’s breast. This can be prevented simply by installing the port primarily in the zone with less soft tissue.
Mohsen Falahati, Fatemeh Dehghani, Mahdi Malakoutikhah, Ali Karimi, Asma Zare, Saeed Yazdani Rad,
Volume 33, Issue 1 (2-2019)
Abstract
Background: Musculoskeletal disorders (MSDs) are considered an important health concern, particularly in automotive assembly industries. Evaluation of the effects of all MSDs risk factors is difficult due to its multifactorial nature. In addition, the risk factors cannot be detected accurately when they are only based on individual opinions. Thus, in this study, fuzzy logic tool was used to evaluate the combined effects of all risk factors on MSDs.
Methods: This cross sectional study was conducted on 100 male workers in an automotive industry. Job satisfaction, job stress, job fatigue, and body posture were evaluated by a self-reported questionnaire. Body posture was evaluated using Rapid Entire Body Assessment (REBA). Primary data analysis on extracting the input variables of MATLAB was performed by SPSS 22, with a significant level of 0.05. T test, one-way Anova, and Pearson correlation analysis were used to extract the input variables for the fuzzy logic model. The results obtained from the Nordic questionnaire was selected as the output of the fuzzy model. Fuzzy logic assessment was performed using MATLAB software version 7.0.
Results: There were significant differences between WMSDs factors, including job fatigue, strain, working posture, and the REBA final score, and pain in all limbs of the body (p<0.05). A significant difference was also found between working posture with wrist score (p<0.05). The findings on defuzzification showed a strong correlation between real and modelling results.
Conclusion: The results showed that many factors such as posture, fatigue, and strain affect MSDs. Based on the obtained results, all categories of risk factors, including personal, psychosocial, and occupational, should be considered to predict MSDs, which can be achieved by a modeling approach.
Shadi Naderyan Feli, Seyed Mojtaba Yassini Ardekani, Hosein Fallahzadeh, Ali Dehghani,
Volume 33, Issue 1 (2-2019)
Abstract
Background: The metabolic syndrome is highly prevalent among patients with schizophrenia. This study was conducted to determine the prevalence of metabolic syndrome and the risk of cardiovascular disease in the next 10 years among schizophrenic patients.
Methods: This cross sectional study was performed on 100 Iranian patients with schizophrenia in 2016. The prevalence of metabolic syndrome was determined by adult treatment panel III criteria, and 10-year cardiovascular risk was calculated by Framingham Risk Score. SPSS software was used to perform statistical analysis. Chi-square and Fisher's exact or extended Fisher's exact tests were used to compare dichotomous variables. Also, Mann-Whitney U test was applied to compare the quantitative variables. Significance level was considered to be less than or equal to 0.05.
Results: In this study, 83 participants (83%) were male and 17 (17%) were female. The prevalence of metabolic syndrome was 27% (21.7% in males and 52.9% in females, p=0.015). Among all components of metabolic syndrome, low HDL-C in men and abdominal obesity in females were the most common disorders. Based on Framingham Risk Score, 76%, 16%, and 8% of patients had low, intermediate, and high level of risk, respectively. A significant difference was observed between the level of risk among participants with and without metabolic syndrome (p=0.042).
Conclusion: In this study, patients with schizophrenia showed a high prevalence of metabolic syndrome, but most of them had low risk of developing cardiovascular disease. These results suggest regular screening and early interventions to modify the risk factors of metabolic syndrome.
Alireza Mohebbi, Farideh Hosseinzadeh, Saleh Mohebbi, Ali Dehghani,
Volume 33, Issue 1 (2-2019)
Abstract
Background: Rhinosinusitis is an inflammatory disease of the nasal and paranasal sinus mucosa, and it becomes chronic when it lasts longer than 3 months without symptom improvement. The aim of this study was to determine the effect of PRP on improvement of endoscopic sinus surgery.
Methods: This was a randomized clinical trial (RCT) designed and implemented on 21 patients with chronic rhinosinusitis in Rasool Akram hospital in Tehran during 2016-2017. In this study, one side of the nose was randomly selected as the control and the other side as the case, and at the end of the surgery, PRP was sprayed onto the surface where the polyp was removed in the side that was intended as the case. The nasal endoscopy findings were graded according to Meltzer’s criteria before and after surgery and CT findings were classified according to the Lund-Mackay scoring system. Then, all patients were followed for 6 months. The SNOT-22 questionnaire, charts of Meltzer’s criteria, and Lund-Mackay were used for data collection. Kolmogorov–Smirnov test, Wilcoxon Signed Rank test, and Mann-Whitney U test were used to analyze data in SPSS-22 software. P value<0.05 was considered significant.
Results: The mean and standard deviation of patients' age were 36.55 and 7.91, respectively. The median Lund-McKay Pre-op CT score before treatment was 10 (9.5-11), and no significant difference was found between the 2 sides of the nose (left and right). The items that showed statistically significant improvement after surgery was SNOT-22 (p<0.05). The mean of Meltzer scores in each side of the nose was significantly different before and after intervention (p<0.05). However, the mean of Meltzer scores in the 2 sides of the nose was not significantly different before and after intervention.
Conclusion: The treatment by PRP may be effective in reducing symptoms of patients showing recurrence of CRS symptoms following endoscopic sinus surgery subjectively but not objectively.
Gholamreza Masoumi, Amir Noyani, Arezoo Dehghani, Ali Afrasiabi, Nahid Kianmehr,
Volume 34, Issue 1 (2-2020)
Abstract
Seyed Hamidreza Bagheri, Alimohamad Asghari, Mohammad Farhadi, Ahmad Reza Shamshiri, Ali Kabir, Seyed Kamran Kamrava, Maryam Jalessi, Alireza Mohebbi, Rafieh Alizadeh, Ali Asghar Honarmand, Babak Ghalehbaghi, Alireza Salimi, Fatemeh Dehghani Firouzabadi,
Volume 34, Issue 1 (2-2020)
Abstract
Background: The occurrence of anosmia/hyposmia during novel Coronavirus disease 2019 (COVID-19) may indicate a relationship between coincidence of olfactory dysfunction and coronavirus disease 2019 (COVID-19). This study aimed to assess the frequency of self-reported anosmia/hyposmia during COVID-19 epidemic in Iran.
Methods: This population-based cross sectional study was performed through an online questionnaire from March 12 to 17, 2020. Cases from all provinces of Iran voluntarily participated in this study. Patients completed a 33-item patient-reported online questionnaire, including smell and taste dysfunction and their comorbidities, along with their basic characteristics and past medical histories. The inclusion criteria were self-reported anosmia/hyposmia during the past 4 weeks, from the start of COVID-19 epidemic in Iran.
Results: A total of 10 069 participants aged 32.5±8.6 (7-78) years took part in this study, of them 71.13% women and 81.68% nonsmokers completed the online questionnaire. The correlation between the number of olfactory disorders and reported COVID-19 patients in all provinces up to March 17, 2020 was highly significant (Spearman correlation coefficient = 0.87, P< 0.001). A sudden onset of olfactory dysfunction was reported in 76.24% of the participations and persistent anosmia in 60.90% from the start of COVID-19 epidemic. In addition, 80.38% of participants reported concomitant olfactory and gustatory dysfunctions.
Conclusion: An outbreak of olfactory dysfunction occurred in Iran during the COVID-19 epidemic. The exact mechanisms by which anosmia/hyposmia occurred in patients with COVID-19 call for further investigations.
Mahdi Alemrajabi, Seyedeh Fahimeh Shojae, Mohammad Moradi, Amin Dehghanian, Amirreza Ehsani, Seyed Soroosh Valinia,
Volume 35, Issue 1 (1-2021)
Abstract
Background: Constipation is one of the most common gastrointestinal discomforts that affects various age groups in humans. Different mechanical cleansing devices have been introduced yet. However, they are very expensive and not available in our country.
Methods: This was a pilot experimental trial. Fifteen patients with eligible ROME III criteria and at least two years of chronic constipation and resistant to medical therapy entered the study. Wexner and Longo's scores were checked before and after using the “Roodeshur” device. Data entered SPSS 16 and analyzed using T-test. A p value below 0.05 was considered as a statistically significant difference.
Results: Five patients were female and 10 males. The mean age of patients was 53.56±18.34 years. There was a significant difference regarding intestinal movement before and after using the device (p˂0.001). Wexner's score decreased after the intervention with a significant difference (p˂0.001).
Conclusion: Our mechanical cleansing device (Roodeshur) was effective and safe for patients with resistance constipation. No complication occurred. Due to its low cost and easy access in our country, it can be recommended for other patients as well. However, more studies with a larger sample size are recommended.
Mahmoud Haghighat, Naser Honar, Mohammad Hadi Imanieh, Maryam Ataollahi, Seyed Mohsen Dehghani, Iraj Shahramian, Fereshteh Karbasian, Hamideh Komeily Fard, Marzieh Soheili, Seyede Maryam Mahdavi Mortazavi,
Volume 37, Issue 1 (2-2023)
Abstract
Background: Large-volume paracentesis has become the first treatment choice for patients with severe and refractory ascites. The studies have reported several complications after therapeutic paracentesis. But there are few published data on the complications with or without Albumin therapy. We aimed to analyze the safety and complications of large-volume paracentesis in children with or without albumin therapy.
Methods: This study was conducted on children with severe ascites with chronic liver disease who underwent large-volume paracentesis. They were divided into albumin-infused and albumin non-infused groups. In the case of coagulopathy, no adjustment was made. Albumin was not administered after the procedure. The outcomes were monitored to evaluate the complications. To compare two groups, a t-test was utilized, and the ANOVA test was used to compare several groups. If the requirements for using these tests were not met, Mann-Whitney and Kruskal-Wallis tests were applied.
Results: Decreased heart rate was observed in all time intervals and was meaningful six days after paracentesis. MAP also decreased statistically at 48 hours and six days after the procedure (P < 0.05). Other variables did not show any meaningful change.
Conclusion: Children having tense ascites with thrombocytopenia, prolonged PT, Child-Pugh class C, and encephalopathy can undergo large-volume paracentesis without any complication. Albumin administration before the procedure in patients with low levels of Albumin (<2.9) can effectively overcome the problems of tachycardia and increased mean arterial pressure. There will be no need for Albumin administration after paracentesis.
Simin Dehghani, Navid Mirzakhany Araghi, Sima Dehghani, Marzieh Pashmdarfard,
Volume 37, Issue 1 (2-2023)
Abstract
Background: Due to the limited access of clients in non-urban areas to rehabilitation and the difficulty of specialized counseling in such conditions, the need for telehealth services has increased. The purpose of this study is to evaluate the effectiveness of Tele occupational therapy in common disorders of children and adolescents.
Methods: In this systematic review study, a research method published from 2010 to 2022 focusing on the effectiveness of tele-rehabilitation and its impact on children and adolescents with different physical disabilities was done in Google Scholar, PubMed, Scopus and EMBASE databases. 467 articles were obtained in the review, and finally, 18 articles were reviewed.
Results: In children with CP, Tele occupational therapy will be effective on gross motor function and balance skills, but the impact on the executive function needs more studies. In children with ASD, it will be effective on behavioral problems, but the effect on pro-social behavior needs further studies. In children and adolescents with other movement disorders, it will have an impact on the progress of their physical activity and in children and adolescents with Traumatic Brain Injury (TBI), it will be effective, but the effectiveness of MitiiTM programs needs further studies.
Conclusion: The findings of this study showed that tele-occupational therapy could be performed in line with face-to-face occupational therapy, and it can lead to the satisfaction of families, but there is still a need to assess the effectiveness of various interventions and tools on different disorders, outcomes and settings.
Marjan Zare, Alireza Mirahmadizadeh, Masoumeh Khosravi, Mohammadreza Karimi, Seyedeh Leila Dehghani,
Volume 37, Issue 1 (2-2023)
Abstract
Background: Concerns about the side effects of SARS-CoV-2 vaccines have been raised nationwide. We aimed to compare the time to report the side effects of the Oxford-AstraZeneca and Sinopharm COVID-19 vaccines.
Methods: Information on side effects of AstraZeneca and Sinopharm COVID-19 vaccines was obtained from the COVID-19 Symptom Study App affiliated with Shiraz University of Medical Science during 2021. A COX regression model with an adjusted Hazard Ratio and 95% Confidence Interval; HR (95% C.I) was reported at the significance level of < 0.05.
Results: 4478 and 5555 participants received the AstraZeneca and Sinopharm vaccines, respectively; more age, history of SARS-CoV-2 infection, first vaccine dose, hypertension, and hypertension with cardiovascular disease were seen in the AstraZeneca group (P < 0.05 for all). However, the AstraZeneca group had lower immune deficiency and time to report the side effects (P < 0.05 for both). There was significantly less time to pain HR(95% C.I.); 0.50 (0.47-0.52), vertigo 0.65 (0.61-0.69), weakness 0.41 (0.38-0.44), headache 0.43 (0.39-0.74), anorexia 0.31 (0.28-0.34), nausea 0.56 (0.51-0.62), severer allergy 0.71 (0.63-0.81), general inflammation 0.27 (0.23-0.31), fever > 38oC 0.12 (0.1-0.15), eye inflammation 0.45 (0.39-0.52), diarrhea 0.85 (0.73-0.99), blurred vision 0.73 (0.61-0.86), injection site redness 0.32 (0.26-0.39), fatigue/paleness 0.53 (0.50-0.57), joint pain 0.55 (0.41-0.73), auxiliary gland inflation 0.59 (0.43-0.80), convulsions 0.30 (0.17-0.52), and severe side effects 0.3 (0.27-0.33) in the AstraZeneca group; However, skin rash 0.77 (0.57-1.05) and hospitalization 0.72 (0.21-2.55) were the same.
Conclusion: Sinopharm COVID-19 vaccine recipients reported longer times to report vaccine-related side effects than AstraZeneca; due to the lack of adverse effects like hospitalization, vaccination should continue to control the pandemic; more real-population studies are needed on the long-term effects of vaccination against COVID-19.
Mahta Arbabi, Zahra Ghaffarinejad, Hossein Dehghani Mohammad Abadi, Sajad Erami, Anahita Esmaeili, Yeganeh Dehghani Mohammad Abadi, Maryam Shojaeifard,
Volume 37, Issue 1 (2-2023)
Abstract
Background: The most challenging risk of mechanical valves is thromboembolic events; therefore, life-long anticoagulation therapy is necessary. Anticoagulation therapy should be adjusted for each patient with serial international normalized ratio (INR) monitoring. Due to the small number of patients with a mechanical valve in the pulmonary position, we are facing a lack of information about the therapeutic range of the INR in these patients. We aimed to evaluate patients with a history of pulmonary valve replacement (PVR) who faced malfunction and compare their INR and echocardiographic data at the time of malfunction and 3 months prior.
Methods: In this cross-sectional study, 71 patients who had previously undergone PVR and presented to Shaheed Rajaie Cardiovascular Medical and Research Center with a diagnosis of pulmonary valve malfunction between 2014 and 2021 were included. Patients' INR and echocardiographic data at the time of the malfunction and 3 months before the malfunction diagnosis were gathered from the hospital's registry. IBM SPSS 20.0 was used for data analysis.
Results: In this cross-sectional study, 71 patients with mechanical pulmonary valve malfunction were included. 49.3% (n = 35) were men, 50.7% (n=36) were women, and their mean age was 33.23 (±8.279). The mean INR of all patients 3 months before malfunction and at the time of malfunction was 2.29 (±0.753) and 2.20 (±0.704), respectively.
Conclusion: In this study, most of our patients had an INR below the therapeutic range, both at the time of malfunction and 3 months prior. It emphasizes the importance of patient follow-up and keeping the INR in the therapeutic range.
