Showing 10 results for Fallahzadeh
Gh Hashemi, Mh Fallahzadeh,
Volume 7, Issue 4 (2-1994)
Abstract
The purpose of this study has been to evaluate various factors influencing
prognosis in children with hemolytic-uremic syndrome (HUS). Forty children with
classical picture of HUS were seen in 1986-1 991. Boys and girls were equally
affected, aged from two months to ten years. In 35 patients (87.5%) there was a
history of diarrhea which was bloody in25. All were treated with peritoneal dialysis
within the first 24 hours. Fresh frozen plasma (FFP) was transfused in the first two
days for all except II patients for whom it was transfused in the third to fifth day of
admission. Fifteen patients died (37.5%) of these, 12 (80%) had diarrhea for longer
than 7 days, II (73%) had prominent neutrophilia, and 9 (60%) had significant
neurological symptoms. Eleven of the fifteen patients had been transfused with FFP
after the third clay of hospitalization. Statistical analysis of data relating to mortality
revealed the following regarding prognostic factors in HUS among children:
mortality is higher in those with longer prodromal period (p<0.001), in those with
bloody diarrhea (p<0.025), in patients with prominent neutrophilia (p<0.001), and
in those who had delayed treatment with FFP (p<0.001). Prognosis was not affected
by age, sex, or season of presentation.
Mh Fallahzadeh, Gh Hashemi, M Shariati,
Volume 13, Issue 2 (8-1999)
Abstract
Most current references recommend divided doses of prednisolone for the
initial treatment of idiopathic minimal change nephrotic syndrome in children,
with relapse occuring in the majority of them, but there is little experience
concerning single-dose prednisolone therapy, especially considering the relapse
rate. In this prospective study on 36 consecutive children with primary nephrotic
syndrome, prednisolone (2 mg/kg/day) was used as a single daily dose in 17
patients (SD group), or divided into 3 doses in 19 cases (DD group) who were
randomly selected, and relapse rates were compared.
The mean age of the patients was 6 years (range 15 months-I3 years)• and there
was no statistically significant difference between the two groups considering age,
sex, clinical presentation, laboratory findings at the time of admission and
prednisolone side effects.
After 4 weeks of full dose prednisolone therapy, the drug was changed to 2 mg!
kg as a single dose every other day in both groups, irrespective of the response.
During the third month of therapy, the drug was reduced to 1 mg/kg every other
day and it was discontinued after 4 weeks.
Relapse rate was compared in steroid responsive patients in both groups (14 in
the SD and 11 in the DD group) who were matched for age, sex and paraclinical
findings. During the first year of follow-up, in those who were initially steroid
responsive, 2 patients in the SD and 6 in the DD group had no relapse. The number
of total relapses/year in the SD and DD group were 19 for 12 patients and 8 for 5
patients respectively (p
Mohammad Hossein Fallahzadeh, Hashemi Ghamar,
Volume 17, Issue 4 (2-2004)
Abstract
In order to avoid using cytotoxic drugs and to minimize prednisolone side effects
in frequent relapsing or steroid-dependent idiopathic nephrotic syndrome, 35 patients,
3 to 15 (mean= 8.1) years of age, were studied. While in remission for at least 6
weeks, the dose of prednisolone was reduced to 0.1-0.37 (mean= 0.23) mg/kg/day as
a single dose for 12 to 72 (mean= 27.6) months. It was followed by a tapering method,
with gradual increase in the interval instead of decrease in the dose for about 10 to 12
months, and about 18.4 months follow-up without treatment. About 54.3% of the patients
had no relapse during the treatment period and the relapse rate per patient per
year was 3.94 during the preceding 12 months before the study, 0.51 during treatment
(p<0.001) and 0.23 after discontinuation of the drug. Each relapse was treated by a
standard dose of prednisolone for 2 months and then the low dose regimen was resumed.
The patients tolerated the drug well with minimal side effects. It is concluded
that long term, low-dose daily prednisolone therapy followed by gradual increase in the
interval is a safe, well-tolerated and effective method of maintaining prolonged remission
in most children with frequent relapsing idiopathic nephrotic syndrome.
Fatemeh Ghane Sharbaf, Mohamad Hosein Fallahzadeh, Alireza Modarresi, Mohamad Esmaeili,
Volume 20, Issue 1 (5-2006)
Abstract
ABSTRACT
Background: Experience with vesicoureteral reflux (VUR) differs in different centers and there are plenty of controversies. The aim of this study was to evaluate the outcome of primary VUR complications and the rate of recurrence of UTI.
Methods: The medical charts of all infants and children with primary VUR who were followed up by two nephrologists were reviewed. During 19 years (1985-2004), 330 patients (271 females, 59 males) with 496 refluxing ureters were followed up as primary VUR.
Results: The patients’ age at diagnosis was 4 days to 16 years (mean: 4.1 years) and the mean duration of follow-up was 4.5 years. Urinary tract infection (UTI) was the presenting symptom in 95% and fever was recorded in 35% of cases. Frequencies of different grades of VUR at initial investigation were 10%, 35%, 30%, 13% and 12% for grades I to V, respectively. Recurrence of UTI in VUR of grades I to V were 22.2%, 18.1%, 20%, 23.4% and 17.9%, respectively. Follow-up voiding cystourethrogram revealed resolution of VUR in 55%, improvement in 27.5%, no change in 12%, and deterioration in 5.5%. Complications such as chronic renal failure and hypertension were observed in 13 and 13 patients, respectively. Renal scarring was present in 52% of boys and 29% of girls.
Conclusion: The present study indicates that symptomatic primary VUR is more common and has better prognosis in girls. Recurrence of UTI is not related to the grade of VUR.
Malek Amini, Aryan Shamili, Bijan Frough, Marzieh Pashmdarfard, Abolghasem Fallahzadeh Abarghouei,
Volume 30, Issue 1 (1-2016)
Abstract
Background: Spasticity is one of the problems after a stroke. Due to this increase in muscle tone, patients are confronted with problems in motor control and difficulties in activities of daily living and complications such as shortness and contracture. The aim of this study was to examine the effects of the simultaneous use of both splint and botulinum toxin-A (BTX-A) injection on spasticity, range of motion and upper extremity function in a 3-month period.
Methods: In this study a comparison was done between three groups of interventions, conducted in rehabilitation clinics in Tehran. Sixty people with chronic stroke were recruited. Based on the inclusion criteria, a total of 39 stroke patients after completing the consent forms were entered to intervention groups; splint or botulinum toxin injection or combined splint/botulinum toxin injection. They were followed up about three months and the evaluations were done monthly. Goniometry was the method to measure the range of motion, and Modified Ashworth Scale was used to examine the spasticity and the upper extremity function was scored based on Fugl-Meyer Assessment. Statistical analysis was done using SPSS 17. And ANOVAs was used for comparison between groups and times. Significance was set at 0.05.
Results: All outcome measures were improved within each group but the differences between splint group and BTX-A group and the BTX-A-splint group was not significant in most outcomes during the 3 periods (first evaluation until end of the first month, the end of first month until the end of second month, the end of second month until the end of the third month) (p>0.05). The results also showed that the changes in elbow`s spasticity (p=0.05) and wrist`s spasticity (p=0.007) and upper extremity function (p=0.04) were obvious between the three groups over the 3-months and the difference in the group of combined use of botulinum toxin, and the splint was more than other groups.
Conclusion: In this study, the effects of botulinum toxin injection and Volar-Dorsal Wrist/Hand Immobilization splint and the combined use of botulinum injection and splint were obvious in all groups but was not significantly different between the interventions in a 3-month follow-up.
Abolghasem Fallahzadeh Abarghuei, Mahsa Fadavi-Ghaffari, Safoura Tousi, Malek Amini, Ali Reza Salehi,
Volume 32, Issue 1 (2-2018)
Abstract
Background: One of the vulnerable populations of any community are the elderly, who are exposed to poor balance, falls, injuries, reduced quality of life (QoL) and independency, and early death. Considering the importance of balance in independently performing activities of daily living (ADL) and its impact on QoL, in this study, we aimed at investigating the effect of Cawthorne and Cooksey exercises (CCE) on QoL and balance of 60 to 80 year-old individuals in Shiraz, Iran.
Methods: This clinical trial study was conducted on forty 80 to 60-year-old individuals of Jahandideghan retirement center in Shiraz (20 in the intervention and 20 in the control groups) in 2014. The intervention group did CCE in three 60- minute sessions a week for 2 months. The balance status of the participants was assessed with Berg balance test, and their QoL was also examined using SF36 Quality of Life Questionnaire before the intervention and at 2 months post intervention. Data were analyzed by independent t test in SPSS software Version 19.
Results: The results of the study revealed that the difference was significant in the balance change scores between the 2 groups (p<0.001, effect size = 0.78). Change differences in the QoL scores were significant between the 2 groups as well (p<0.001, effect size = 0.39).
Conclusion: CCT improved QoL and balance of 60 to 80 year- old Shirazians, so considering the low cost, easy implementation, and considerable impact of the exercises, CCT could be used to prevent and treat balance disorders of the elderly.
Abolghasem Fallahzadeh Abarghuei, Afsoon Hassani Mehraban, Laleh Lajevardi, Mahin Yousefi,
Volume 32, Issue 1 (2-2018)
Abstract
The ICF (the international classification of functioning, disability, and health) is a globally agreed framework and classification to define the spectrum of problems in the functioning of patients. ICF tools were developed based on ICF Core Set (ICF-CS) for the clinical application of ICF and patient management in the rehabilitation process. The current case report aimed at using ICF-based documentation tools in the occupational therapy process in a patient with chronic stroke. The case was a male who had a stroke 6 months prior to the study. The occupational therapy provided to this patient included 5 patient management components (examination, evaluation, prognosis, diagnosis, and intervention) using the ICF-based documentation tool. After one month, improvement in balance and mobility, going up and down the stairs without help, independent upper and lower body dressing achieved. The ICF was clinically applied to the occupational therapy practice in this case report. Because of the close relationship of ICF tools with the concept of occupational therapy, particularly client-centered approach and holistic evaluation of patients, occupational therapists can use ICF in clinical practice to have a more comprehensive view toward patients’ recovery.
Shadi Naderyan Feli, Seyed Mojtaba Yassini Ardekani, Hosein Fallahzadeh, Ali Dehghani,
Volume 33, Issue 1 (2-2019)
Abstract
Background: The metabolic syndrome is highly prevalent among patients with schizophrenia. This study was conducted to determine the prevalence of metabolic syndrome and the risk of cardiovascular disease in the next 10 years among schizophrenic patients.
Methods: This cross sectional study was performed on 100 Iranian patients with schizophrenia in 2016. The prevalence of metabolic syndrome was determined by adult treatment panel III criteria, and 10-year cardiovascular risk was calculated by Framingham Risk Score. SPSS software was used to perform statistical analysis. Chi-square and Fisher's exact or extended Fisher's exact tests were used to compare dichotomous variables. Also, Mann-Whitney U test was applied to compare the quantitative variables. Significance level was considered to be less than or equal to 0.05.
Results: In this study, 83 participants (83%) were male and 17 (17%) were female. The prevalence of metabolic syndrome was 27% (21.7% in males and 52.9% in females, p=0.015). Among all components of metabolic syndrome, low HDL-C in men and abdominal obesity in females were the most common disorders. Based on Framingham Risk Score, 76%, 16%, and 8% of patients had low, intermediate, and high level of risk, respectively. A significant difference was observed between the level of risk among participants with and without metabolic syndrome (p=0.042).
Conclusion: In this study, patients with schizophrenia showed a high prevalence of metabolic syndrome, but most of them had low risk of developing cardiovascular disease. These results suggest regular screening and early interventions to modify the risk factors of metabolic syndrome.
Abolghasem Fallahzadeh Abarghuei, Mohammad Taghi Karimi,
Volume 36, Issue 1 (1-2022)
Abstract
Background: One of the most important approaches in the rehabilitation of spinal cord injury (SCI) patients is the use of different orthoses. To date, no review has been published that analyzed the effects of orthoses on health aspects of spinal cord injury clients using the International Classification of Functioning, Disability and Health (ICF).
Methods: A systematic literature search was done in some databases, including Medline, PubMed, Cochrane centered register of the controlled trial (CCTR), Cochrane database of systematic reviews (CDSR), a database of abstracts of reviews of effects (DARE), Embase, Google Scholar, and ISI Web of Knowledge. SCI was used in conjunction with terms like orthotic device, mechanical orthoses, external power orthoses, assistive devices, and functional electrical. The time frame for this search was from 1970 to 2022.
Results: A total of 200 papers were found. Based on the titles and abstracts, 100 related papers were detected. After careful evaluation of the papers, 47 studies were selected for final analysis—53 papers were excluded due to duplication, non-English language, and lack of full-text.
Conclusion: The results of 32 studies (70% of studies) support the efficiency of orthoses in walking and standing of SCI patients. In most of the included studies, the efficiency of orthoses was evaluated mostly based on body functions and structures, and their impact on other outcomes such as participation and quality of life (QoL) of SCI patients was unclear.
Mohammad Taghi Karimi, Abolghasem Fallahzadeh Abarghuei,
Volume 38, Issue 1 (1-2024)
Abstract
Background: Thoracolumbar fractures are common traumatic injuries that can be treated conservatively or by surgery, depending on the type and severity of the injury. This study aimed to determine the efficiency of various orthoses used for these fractures based on the available literature.
Methods: Between 1950 and 2023, a search was conducted in some databases, including PubMed Central and MEDLINE, ISI Web of Knowledge, Cochrane-centered Register of Controlled Trial (CCTR), Embase, and Scopus. Some keywords—such as conservative treatment, orthoses, brace, and cast—were used in combination with thoracolumbar fracture, burst fracture, and compressive fracture. The quality of the studies was evaluated using the PEDro scale. Two researchers independently reviewed the studies.
Results: Based on the results of the included studies, orthosis is not necessary for stable burst and compression fractures. Based on the inclusion criteria, 20 papers were selected for the final analysis, 12 of which were on the use of spinal braces and casting (with quality between 1 and 6), 2 on the no-treatment approach, and 6 on comparing the outputs of treatment with spinal braces with no braces.
Conclusion: Although the use of orthosis and cast is one of the conservative treatments recommended for patients with thoracolumbar fractures, it seems that for stable burst fractures and compression fractures, the use of a brace does not provide any benefits. However, the use of a brace or cast is recommended for burst fractures with more than 1 column fracture.
