Showing 19 results for Noori
Mr Noori-Daloii, N Moazami, M Izadyar, S Farhangi, F Beyrami Jamal, A Atalay, Ln Geren, L Akar, E Atalay, B Cirakoglu, E Bermek,
Volume 8, Issue 2 (8-1994)
Abstract
By application of modern recombinant DNA technology, especially the
polymerase chain reaction (PCR)/dot-blot hybridization techniques, we have
investigated the molecular basis of β-thalassemia from four different regions of Iran:
central, south-east, south and north. In this study, the DNA samples were isolated
from patients and for the identification of the mutations, the 6 oligonucleotide probes
for the mutations of IVS.1/nt. 110, .lVS.1/nt.6, IVS.1/nt.1 , nonsense codon 39,
frameshift codon 8 and IVS. 2/nt.1 were selected with respect to their relative
frequency in the neighbouring country, Turkey. Four mutations accounted for76.2%
and of these, the most frequent was the nonsense codon 39 mutation, which accounts
for 60.3% of the β-thalassemia alleles tested. The remainder, in decreasing order of
frequency, wereframeshift codon 8(9.5%), lVS. 1/nt.6 (4.8%) and IVS.1/nt.11O(1.6%).
No hybridization was observed with the probes corresponding to the mutations of
rvS.I/nt I (0/ A) and rvS.2/nt.1 (0/ A). These results also revealed that the distributions
of different types of mutations were different in the four regions. This information
and the introduction to the methodology used in this study will facilitate the prenatal
diagnosis of the disease in Iran.
Morteza Afrasiabi, Zahra Zolnoorian, Seyyed Hossein Javadpoor,
Volume 8, Issue 4 (2-1995)
Abstract
The pharmacokinetics of recombinant human erythropoietin (rHuEpo)
administered intravenously has been investigated in a group of five patients with
chronic renal failure who were dialysis-dependent. The half-life of circulating
erythropoietin decreased from 7.9±OA hr (mean ±SO) at the beginning of treatment
to 6.2±O.6 hr after 6 weeks and 5A±O.9 hr after 4 months of treatment. In spite of the
sustained increase in haemoglobin neither the red ce1l2,3,-diphosphoglycerate (2,3-
DPO) nor the P50 decreased from the pretreatment values. The mechanism which
governs the rise in 2,3-diphosphoglycerate in chronic renal failure is different from
the adaptive mechanism which operates in other types of anaemia.
P Mehdipour, M Saadat, Mr Noori-Daloii,
Volume 10, Issue 1 (5-1996)
Abstract
Cytogenetic studies were performed on 150 cases of Down's syndrome (DS)
in Iran. The standard trisomy 21 was found in 132 (88 % ) and translocation-trisomy
21 (+21) in 18 (12%) patients, i.e., t(21,21) in 1(0.63%) and mosaicism in
17(11.33%) cases.
The comparison of the frequencies for mosaicism between different
populations such as Denmark, Hungary, Egypt, Iraq, India, Australia and Iran
demonstrated a difference in geographic distribution. There was a high incidence
in the north of Europe towards Egypt and Iraq which decreased towards Iran and
further towards the eastern region in the Indian ocean and India and further
decreased towards Australia. Statistical analyses demonstrated significant
differences between the data in Iran and Copenhagen, Hungary and Australia for
mosaicism and translocation +21, and India, for translocation +21. The occurrence
of translocation +21 decreased significantly from Denmark towards Egypt in
Africa and Iraq in southwest Asia, then it increased from Iran towards Australia
in the Pacific ocean.
The comparison of cells having satellite associations (SA), significantly
indicated the involvement of two and three SAs in DS cases.
The study on the position of chromosomes in the metaphase plate, the
occurrence of chromatid breaks and endoreduplication did not present any
significance in DS cases.
Mr Noori-Daloii, Ha Sasan, S Mohaghegh Hazrati,
Volume 12, Issue 2 (8-1998)
Abstract
Shahla Bahremand, A. Zamani, H. Foroutan, Faroukh Tirgari, Shamsollah Nooripour, Laleh Razavi, Heshmat Moayeri,
Volume 19, Issue 1 (5-2005)
Abstract
ABSTRACT
Background: Triple therapy with a proton pump inhibitor, clarithromycin and amoxicillin and quadruple therapy with a proton pump inhibitor, bismuth citrate, metronidazole and amoxicillin have been proposed in Maastricht 2000 as the optimal treatment of Helicobacter pylori infection. We aimed to compare these two regimens in Iranian pediatric patients.
Methods: A randomized clinical trial in Em am Khomeini Hospital between 13 81 and 1382 was done. Patients with confirmed H. pylori infection by histology were divided in to two groups in a randomized 1: 1 scheme. Triple regimen group: Clarithromycin 15 mg/kg/d, Amoxicillin 50 mglkg/d and Omeprazole 1 mg/kg/day for 10 days. Quadruple regimen group: Omeprazole 1 mg/kg/d, Amoxicillin 50 mglkg/day, Metronidazole 20 mglkg/day and Bismuth citrate 8 mglkg for 10 days. The eradication was assessed by c-urea breath test 4 weeks after the end of treatment and byperprotocol analysis.
Results: In our study, 100 patients (50 in each group) were found and the eradication rates in the triple and quadruple group were 92% and 84% respectively (p=0.046).
Conclusion: According to our results, we recommend triple therapy as first-line treatment in Iranian pediatric patients and quadruple therapy as a second line regimen.
Mohammad Reza Noori-Daloii, Mohammad Reza Alivand, Parisa Atef-Vahid, Feyzollah Hashemi-Gorji, Mehrdad Hashemi,
Volume 24, Issue 2 (8-2010)
Abstract
Abstract
Background: Several studies suggested that some traits and polymorphisms in human genome such as G6PD deficiency and other genes have protective effects on susceptibility to malaria infection .
Methods: In present study we investigated the prevalence of TNF [1] -244GgA, TNF [1] -
308 GgA,TNF [1] -238GgA, NOS2-954GgC, MBL54GgA, MBL 57GgA, MBL IVSI -
5 GgA polymorphisms and G6PD variants (Mediterranean, Chatham, Cosenza, A -
(202,376) in 315 subjects with G6PD deficiency and 10 malaria patient. All the 315 subjects were selected from five provinces (Fars, Khuzestan, Esfahan, Yazd and Kerman and screened by PCR-RFLP method .
Results: The NOS2-954GgA consisted GG(40.31%), GC(53.01%), and CC(6.66% )
where as TNF [1] -308 consisted GG(68.8%), AG(31.11% ) contents. The TNF [1] -244
showed GG(94.60%), AG(5.39%) genotypes and the TNF [1] -238 had GG(92.69% ),
AG(6.66%), AA(0.63%) genotypes. The MBL54 polymorphism had GG(75.55%), AG (24.44%), AA(0.63%) genotypes. In MBL 57, had GG(95.23%), AG(4.76%), AA (0.63%) genotypes. The G6PD variants was indicated that Mediterranean mutation in Fars, Khuzestan, Esfahan, Yazd and Kerman provinces was 79.4%, 58%, 83/8%, 64% and 63% respectively and also, the Chatham mutation was 8.8%, 8% 4.5%,3.6% and 0% respectively. Analysis of other four mutations (Cosenza, Arures and A-202 and A-367 ) showed that none of them had those mutations .
Conclusion: Our results suggested that genotypes which causes protection against
malaria or reduction of risk for celebral malaria and death has the maximum prevalence in samples taken from the five provinces, but in the kolmogorov-smiranov test results, only NOS2-954GgC supported the theory of relation between these polymorphisms and protection against malaria .
Ladan Marbouti, Hassan Jafari, Shohreh Noorizadeh-Dehkordi, Hamid Behtash,
Volume 25, Issue 1 (5-2011)
Abstract
Abstract
Background: Low Back Pain (LBP) is still a medical problem in 21 st century. Having back pain and being
disabled by it are not the same thing. It is common to come across with patients who have simple back pain but surprisingly totally disabled and vice versa. In clinical practice, it is important to have a proper evaluation of disability and making a clear distinction between pain and disability. During the past two decades several selfreport measures and questionnaires have been developed to evaluate disability in LBP patients, however most of these questionnaire were designed in English language and based on European or American studies. The aim of this study was to develop and validate a translated and culturally adapt “Pain Disability Index (PDI)” and “Pain Disability Questionnaire (PDQ)” among Iranian patients with low back pain.
Methods: The Persian versions of the PDI, PDQ were created through systematic translation and crosscultural adaptation of the original questionnaires. The Oswestry Disability Index and Visual Analogue Scale were used for validation studies. Patients were asked to complete these questionnaires initially and also at 7 days later as retest.
Results: A total of 304 patients with acute and chronic LBP completed the Persian versions of PDI, PDQ,
“Oswestry Disability Index” (ODI) and “Visual Analogue Scale” (VAS). Among patients 111 patients participated for retest after seven days. The Cronbach’s alpha (coefficient of reliability) for the PDI and PDQ was satisfactory. The PDI and PDQ showed high and very high test-retest reliability (ICC=0.8 and 0.92 respectively). The Pearson correlation coefficient among PDI, PDQ with ODI was 0.64 and 0.72, and for PDI, PDQ, ODI with VAS was 0.36, 0.47 and 0.57, respectively (P<0.001).
Conclusion: The Persian version of the PDI and PDQ questionnaires are reliable and valid instruments to evaluate generic perceived disability in Persian-speaking patients with LBP. It is shown that PDI and PDQ are capable of measuring the disability in LBP patients. They could be used in clinical and research encounters with acceptable confidence.
Maryam Fayazi, Shohreh Noorizadeh Dehkordi, Mehdi Dadgoo, Masoud Salehi,
Volume 26, Issue 1 (2-2012)
Abstract
Background: The Motricity Index was used to measure strength in upper and lower extremities after stroke. The weighted score based on the ordinal 6 point scale of Medical Research Council was used to measure maximal isometric muscle strength. There is dearth of articles dealing with the reliability of this method. Therefore, the aim of this study was to determine the test retest reliability of Motricity Index strength assessments for paretic lower limb in 20 chronic stroke patients with one week interval.
Methods: In a cross sectional study, intrarater reliability of lower extremity Motricity Index strength assessments with one week interval were measured.
Result: The SPSS 18 was used for analysis of data. Two-way random-consistency model of ICC was used for assessment of test-retest reliability. The ICC values showed high reliability of strength measurement of Motricity Index (ICC=0.93).
Conclusion: The Motricity Index can be a reliable instrument for measuring the strength of involved lower extremity when assessment is done by one rater following chronic stroke.
Nasrin Salehi Dehno, Shohreh Noorizadeh Dehkordi, Mehdi Dadgoo, Masoud Salehi,
Volume 26, Issue 4 (11-2012)
Abstract
Background: Consequences of cerebral palsy in adulthood can affect physical, psychological capabilities and quality of life. The purpose of this study was to investigate the relationship between quality of life with spasticity and level of motor function in Iranian young adults with spastic cerebral palsy who were community dweller. Methods: In an analytical cross sectional study, 77 participants with spastic cerebral palsy (44 women، 33 men) with age range of 20 to 40 years (mean age 26.19±5 yr) took part in this study. They were enrolled from three Raad Rehabilitation Goodwill complexes in Tehran and Karaj cities. All subjects were recruited through convenient sampling. Severity of Spasticity for knee flexors was measured with Modified Tardieu Scale. In addition, the level of motor function, and quality of life were assessed respectively through Gross Motor Function Classification System and World Health Organization Quality of life questionnaire (WHOQOL- BREF). To analyze data, Pearson and spearman correlation coefficient was used.
Results: No correlation found between quality of life with knee flexor muscles spasticity and level of motor function (p> 0.05). Conclusion: Quality of life as a multi dimensional concept has been impacted by many factors such as physical status, environmental issues and culture. Possibly, severity of spasticity and level of function have a less pronounced effect on quality of life in community dwelling adults with cerebral palsy.
Reza Dehnavieh, Nadia Mirshekari, Sara Ghasemi, Reza Goudarzi, Ali Akbar Haghdoost, Mohammad Hossain Mehrolhassani, Zahra Moshkani, Somayeh Noori Hekmat,
Volume 30, Issue 1 (1-2016)
Abstract
Background: Every year millions of dollars are expended to equip and maintain the hospital sterilization centers, and our country is not an exception of this matter. According to this, it is important to use more effective technologies and methods in health system in order to reach more effectiveness and saving in costs. This study was conducted with the aim of evaluating the technology of regional sterilization centers.
Methods: This study was done in four steps. At the first step, safety and effectiveness of technology was studied via systematic study of evidence. The next step was done to evaluate the economical aspect of off-site sterilization technology using gathered data from systematic review of the texts which were related to the technology and costs of off-site and in-site hospital sterilization. Third step was conducted to collect experiences of using technology in some selected hospitals around the world. And in the last step different aspects of acceptance and use of this technology in Iran were evaluated.
Results: Review of the selected articles indicated that efficacy and effectiveness of this technology is Confirmed. The results also showed that using this method is not economical in Iran.
Conclusion: According to the revealed evidences and also cost analysis, due to shortage of necessary substructures and economical aspect, installing the off-site sterilization health technology in hospitals is not possible currently. But this method can be used to provide sterilization services for clinics and outpatients centers.
Fereshteh Eftekharizadeh, Reza Dehnavieh, Somayeh Noori Hekmat, Mohammad Hossein Mehrolhassani,
Volume 30, Issue 1 (1-2016)
Abstract
Background: Super oxidized water (SOW), as a novel antiseptic solution, is used with claims of effectiveness and cost effectiveness in healing chronic wounds such as diabetic foot, infectious post-operative ulcers and burn ulcers. We conducted a health technology assessment to evaluate the clinical evidence from clinical and randomized trials for this disinfection. This study aims to evaluate the safety, effectiveness and cost-effectiveness of this technology in Iran, for using as a wound disinfectant.
Methods: Systematic literature searches were conducted from October 2013 to March 2014 for the following medical databases: OVID MEDLINE, CINAHL, the Cochrane Library and the PICO terms were included and then analyzed by Cochrane assessment criteria.
Results: Out of 705 articles, twelve potentially relevant trials were identified. Others that didn’t come with the PICO criteria were excluded. 5 randomized controlled trials, 5 clinical trials, a rapid HTA and a case series that had studied the effectiveness of super oxidized water on patients with different chronic wounds, were included. Most of these trials were assessing similar sets of outcomes as the Safety and Effect on Healing days to re-epithelization, healing rate, effect on Infection bacterial counts and infection rates.
Conclusion: Super oxidized water is a safe, effective and cost effective irrigation and cleansing agent due to the performed analysis in comparison with current treatment as povidone iodine for treating wound infections.
Hassan Hashemi, Ali Akbar Haghdoost, Mohammad Haji-Aghajani, Ghasem Janbabaee, Ali Maher, Somayeh Noori Hekmat, Amir M. Javadi, Rohaneh Rahimisadegh, Samira Emadi, Mahamad Reza Rajabalipour, Hajar Haghighi, Reza Dehnavieh, Masoud Ferdosi, Gholamreza Khademi, Mohammad Hossein Mehralhasani, Asma Sabermahani, Kaveh Nouhi Bezanjani, Abedin Iranpour, Hamidreza Rashidi Nejad, Fatemeh Moeen Samadani, Maryam Maki, Behzad Kalantari, Nahid Farrokhyar, Hamed Rouhanizadeh, Monireh Falakbaz, Hamid Allahyari, Mohammad Taghi Fathalian, Ali Reza Khajehmirzaei, Ali Jannati, Javad Derakhshani, Ali Rezapour, Jamal Eftekhari, Parisa Khaterneshanian Fam, Mahmoud Kazemi, Mohsen Mohammadi, Payam Rastbin, Bahareh Pirhayati, Elahe Souri, Amin Torabipour, Mohammad Keshvari,
Volume 32, Issue 1 (2-2018)
Abstract
Introduction: Hospital beds, human resources, and medical equipment are the costliest elements in the health system and play an essential role at the time of treatment. In this paper, different phases of the NEDA 2026 project and its methodological approach were presented and its formulation process was analysed using the Kingdon model of policymaking.
Methods: Iran Health Roadmap (NEDA 2026) project started in March 2016 and ended in March 2017. The main components of this project were hospital beds, clinical human resources, specialist personnel, capital medical equipment, laboratory facilities, emergency services, and service delivery model. Kingdon model of policymaking was used to evaluate NEDA 2026 development and implementation. In this study, all activities to accomplish each step in the Kingdon model was described.
Results: The followings were done to accomplish the goals of each step: collecting experts’ viewpoint (problem identification and definition), systematic review of the literature, analysis of previous experiences, stakeholder analysis, economic analysis, and feasibility study (solution appropriateness analysis), three-round Delphi survey (policy survey and scrutinization), and intersectoral and interasectoral agreement (policy legislation).
Conclusion: In the provision of an efficient health service, various components affect each other and the desired outcome, so they need to be considered as parts of an integrated system in developing a roadmap for the health system. Thus, this study demonstrated the cooperation process at different levels of Iran’s health system to formulate a roadmap to provide the necessary resources for the health sector for the next 10 years and to ensure its feasibility using the Kingdon policy framework.
Rohaneh Rahimisadegh, Ali Akbar Haghdoost, Samira Emadi, Somayeh Noori Hekmat,
Volume 35, Issue 1 (1-2021)
Abstract
Background: The health sector evolution plan was implemented in 2014 in government hospitals across the country as a part of the universal health coverage achievement programs. This study assessed the performance of hospitals before and after the implementation of this plan, using the Pabon Lasso model.
Methods: The population of this study consisted of the hospitals of the country in the 2013-2015 time frame; overall, 874 hospitals (94.5% of the population) were included in the study. In order to assess performance, we used the Pabon Lasso model and hospital performance indicators (Average Length of Stay, Bed Turnover, and Bed Occupancy Rate). The data were collected from the Hospital Information System and provincial deputies of curative affairs and were then analyzed using the descriptive indicators of mean, frequency, and median in SPSS 22. Also, Paired Student T-test and ANOVA were used to compare the performance of different groups of hospitals before and after the implementation of the health sector evolution plan.
Results: The implementation of the health sector evolution plan has led to a significant improvement in the three performance indicators in the hospitals of the country. Before the implementation of the health sector evolution plan, the most inefficient, inefficient, fairly efficient, and most efficient zones included 31%, 18%, 17%, and 33% of the studied hospitals, respectively. However, the implementation of the health sector evolution plan changed the percentages to 29%, 21%, 20%, and 30%, respectively. Teaching hospitals, which are governmental and are mostly located in capital cities of the provinces, were overall more inefficient than non-teaching hospitals.
Conclusion: The number of the most efficient and most inefficient hospitals has decreased, and the number of average performance hospitals has increased after the implementation of the health sector evolution plan. Therefore, the health sector evolution plan has not led to an overall increase or decrease in the performance of hospitals but has reduced the difference in the performance of hospitals. Equal support of government hospitals along with financial protection against health expenses, improves the performance indicators of hospitals and reduces performance differences among them.
Soheila Aminimoghaddam, Bahareh Fooladi, Maryam Noori, Zeynab Nickhah Klashami, Armita Kakavand Hamidii, Mahsa M. Amoli,
Volume 35, Issue 1 (1-2021)
Abstract
Background: Endometrial cancer is the fourth most widespread cancer among females, with a growing prevalence in recent years. Management by combined therapies along with surgery, radiotherapy, and chemotherapy have improved patients’ prognoses. Besides, the development of new therapies helps preserve fertility and prognosis in aggressive tumors.
The purpose of this research was to identify the efficacy of metformin on the H19 long non-coding RNA expression in endometrial cancer to provide further insight into the pathogenesis and treatment of the disease.
Methods: A total of 23 patients with endometrial cancer, diagnosed by biopsy or diagnostic curettage, were recruited and divided into three groups, before and after metformin treatment and placebo. Real-time PCR was used to evaluate the H19 expression in cancer tissue in all patients.
Results: It has been observed that in endometrial tissue of the “after-metformin” treatment group, the H19 expression level was significantly reduced, compared with the “before-metformin” treatment group, but not in comparison with the placebo. These findings indicate that metformin reduced the H19 expression in endometrial cancer.
Conclusion: Anti-diabetic drugs, such as metformin, may be beneficial by reducing the H19 expression in endometrial cancer due to the H19 relation to cancer progression.
Ali Mirzajani, Foroozan Narooie-Noori, Rasoul Amini Vishteh, Zahra Mirsharif, Samaneh Azampour, Hoda Medhat, Seyyedeh Sara Motahar,
Volume 36, Issue 1 (1-2022)
Abstract
Background: Pregnancy-induced changes in the physiological responses during the gestational period can affect the eye. This study aimed to evaluate the effect of pregnancy on visual, refractive, vergence, and accommodative status.
Methods: In this cross-sectional study, twenty-five healthy pregnant women with a mean age of 29±3.1 were examined. All of the subjects underwent comprehensive ophthalmologic examinations, including anterior segment and fundus examinations and tonometry. Refractive error was determined in each trimester using Autokeratometer. Furthermore, near the point of convergence (NPC), best-corrected visual acuity (BCVA), and near the point of accommodation (NPA) were measured. Data analysis was performed using SPSS version 22. To compare the data during pregnancy, repeated measures analysis of variance (ANOVA) was performed.
Results: During pregnancy, in the right and left eye, spherical equivalent (SE) had a myopic shift from -0.13 to -0.35 D and +0.096 to -0.23 D, respectively (p=0.049 and p=0.020, respectively). Also, in the right and left eyes BCVA significantly decreased from -0.13 to 0.00 and -0.14 to 0.00 LogMAR, respectively (p=0.039 and p=0.045, respectively). NPA and NPC did not change statistically significantly during pregnancy (p=0.385, and p=0.801, respectively).
Conclusion: Due to the unstable hormonal status, a myopic shift and decrease in BCVA occur during pregnancy. So, any change in their spectacle prescription, fitting of contact lenses, performing refractive surgeries, etc., during this period should be postponed.
Alireza Ghaznavi, Mehdi Mohammadpour, Arash Noori, Maziar Rajei,
Volume 37, Issue 1 (2-2023)
Abstract
Background: Local epidemiological data are necessary to identify the disease hot spots and running screening programs. In this study, we evaluated the demographic characteristics of developmental dysplasia of the hip (DDH) in a tertiary referral hospital in Iran.
Methods: In a retrospective study, the medical profiles of 137 DDH children, who were referred to our university hospital between 2014 and 2020, were reviewed for characteristics such as gender, place of birth, age at the diagnosis, gestational age (term or preterm), twin or single birth, mother's age, pregnancy number, breech presentation, associated deformity, family history of DDH, et cetera.
Results: The study population included 24 (17.5%) boys and 113 (82.5%) girls with a mean age of 2.3 ± 2 years. In the majority of cases (54.2%), it was the firstborn. Twin delivery was seen in only 5 (4.1%) cases. The associated deformity was noticed in 17 (12.4%) patients. Clubfoot was the most commonly associated deformity that was seen in 6 of 17 (35.3%) patients. A family history of DDH was recorded in 12 (8.8%) patients. The breech presentation was recorded in 19 (13.9%) patients. The mean age of the mother at the delivery was 27.2 ± 6.1 years. Tehran, Lorestan, Kurdistan, and Khuzestan provinces had the most referrals.
Conclusion: DDH is associated with the female sex, positive family history, breech presentation at delivery, clubfoot deformity, and geographic district. These associations could be used for identifying the disease hot spots and running screening programs for earlier detection and better management of DDH.
Sanaz Bemani, Javad Sarrafzadeh, Shohreh Noorizadeh, Saeed Talebian, Reza Salehi, Jamileh Zarei,
Volume 37, Issue 1 (2-2023)
Abstract
Background: Quantitative electroencephalography (EEG) power spectra analysis was applied to assess brain activation during chronic pain. Although many studies have shown that there are some common characteristics among individuals suffering from various pain syndromes, the data remains inconclusive. The present study aimed to assess chronic low back pain (CLBP) based on functional brain changes with EEG in CLBP patients compared with healthy controls.
Methods: Multichannel electroencephalogram data were recorded from 30 subjects with CLBP and 30 healthy controls under eye-open resting state conditions and active lumbar forward flexion, and their cortical oscillations were compared using electrode-level analysis. Data were analyzed using a pair t-test.
Results: A total of 30 patients (19 men and 11 women in the case group (mean [SD] age, 35.23 [5.93] years) with 30 age and sex-match healthy controls participated in the study. A paired t-test was applied to identify whether there was any difference in the absolute and relative power of frequency spectra between CLBP patients and healthy controls. The results showed a significant increase in alpha relative power in CLBP patients compared with healthy controls in an open-eye resting state (P < 0.050) and active lumbar forward flexion (P < 0.050).
Conclusion: The enhanced alpha relative power in CLBP patients could be relevant to attenuating sensory information gating and excessive integration of pain-related information. Increased power at the EEG seems to be one of the clinical characteristics of individuals with CLBP. EEG can be a simple and objective tool for studying the mechanisms involved in chronic pain and identifying specific characteristics of CLBP patients.
Hamed Tayyebi, Sajad Noorigaravand, Mohammad Reza Baheaddini, Elham Mohammadyahya, Ava Parvandi, Saeid Shirvani, Ali Yeganeh,
Volume 38, Issue 1 (1-2024)
Abstract
Background: In extra-articular distal femoral fractures (EDFFs), nonunion is a serious complication that occurs rarely. In this study, we examined how longer preservation of initial fracture hematoma by delaying the osteosynthesis (OS) affects the fracture union.
Methods: In a retrospective cohort study, 98 EDFF patients were included. The OS was done within 2 days of injury in 50 patients (early OS group) and after 2 days of injury in 48 patients (late OS group). Time to callus formation and fracture union, bleeding amount, surgical duration, pain, knee range of motion, knee function, and postoperative complications, including the nonunion, knee deformity, infection, and revision, were compared between the 2 groups. Statistical analyses were done with SPSS. A comparison of the mean between the 2 groups was made with an independent t test or its nonparametric counterpart. A comparison of categorical variables between the 2 groups was made using a chi-square or the Fisher's exact test. P ˂ 0.05 was considered statistically significant.
Results: The mean time to callus formation was 47.1 ± 17.3 days in the early OS group and 46.9 ± 19.7 in the late OS group (P = 0.950). The mean time to fracture union was 114.9 ± 21 in the early OS group and 117.4 ± 28.8 days in the late OS group (P = 0.630). The mean operation time and bleeding amount between the 2 groups did not differ significantly (P = 0.230 and P = 0.340, respectively). The knee range of motion, pain, and function were not notably different (P = 0.620, P = 0.790, and P = 0.770, respectively). Nonunion occurred in 3 patients of early OS and 2 patients of the late OS group. Other complications were also comparable in the 2 study groups.
Conclusion: Delayed OA in EDFF patients has no significant effect on bone healing and fracture union. Future standard studies are required to confirm these results.
Maryam Taghinezhad, Shohreh Noorizadeh Dehkordi, Marzieh Yassin, Javad Sarrafzadeh,
Volume 38, Issue 1 (1-2024)
Abstract
Background: To review the educational program of physical therapy students at the basic level, it is necessary to understand the challenges and problems faced by physical therapy graduates when working with the elderly. This study aimed to explain the deficiencies of the basic level educational program of physical therapy students with a qualitative study of the content analysis type.
Methods: In-depth and semi-structured face-to-face interviews were conducted in qualitative research with a content analysis approach, with 13 physical therapists with at least 1 year of experience in the specialized field of geriatrics. The obtained data were analyzed using Granheim and Loudman's content analysis method.
Results: A total of 29 codes of the physical therapy program defects in the field of geriatrics were obtained and placed in the 3 main categories as follows: The physical therapist’s knowledge, the physical therapist’s attitude, and the physical therapist’s skill.
Conclusion: The findings indicated that revisions are necessary to the undergraduate physical therapy training curriculum. It is possible to provide a lesson unit with a holistic approach to the elderly in the form of a physical therapy unit for the elderly, as well as valid instructions and guidelines in the field of aging for physical therapists. This can be done through basic or master's level internships in elderly care centers.
