Showing 13 results for Omran
Ghr Omrani, Py Kumar, S Tabei, M Khoddami,
Volume 8, Issue 1 (5-1994)
Abstract
377 patients with single thyroid nodule who clinically were candidates for
surgery, were selected from the patients that referred to the clinics of endocrinology
at Namazee Hospital, Shiraz Medical School. Fine needle aspiration (FNA) was
carried out without performing thyroid scan and the results were compared with
histology obtained by surgery to establish its accuracy in our center. which is an area
of endemic goiter. 72% were benign confirmed by surgery, 17% malignant(of which
two cases were colloid goiter) and II % (42 cases) were suspicious: of these 42
suspicious cases, 28.5% were follicular carcinoma and the rest were benign. In this
study sensitivity and specificity of FNA were 91 % and 97%, respectively. In
conclusion, although our area is an endemic goiter area, the accuracy of FNA is
comparable to iodine sufficient areas.
Ghr Omrani, A Farhadl, A Parhlzgar, S Ardehall, M Haghshenas,
Volume 8, Issue 2 (8-1994)
Abstract
Visceral leishmaniasis is the second most common cause of fever of unknown
origin in our study. This disease is not common in adults, although it's endemic
among the pediatric age group. The majority of the affected individuals were young.
High grade spiking fever, chills and splenomegaly were unique findings. Other
common findings were neutropenia, anemia, abnormal liver function tests, sterile
pyuria and microscopic hematuria. Except for I case, parasites were absent from
tissue biopsies (e.g. bone marrow, liver, lymph node). Diagnosis was suggested by
indirect fluorescent antibody (IFA) and confirmed by response to meglumine
antimonate (Glucantime) and decline of IFA titer on follow-up.
Me Parsanezhad, M Raoofi, S Alborzi, Gh Omrani,
Volume 17, Issue 3 (11-2003)
Abstract
In order to evaluate the effects of short course administration of dexamethasone
(DEX) combined with clomiphene citrate (CC) in CC-resistant patients with
polycystic ovary syndrome (PCaS) and normal DHEAS, a prospective, double
blind, placebo controlled, randomized study was undertaken at referral university
hospitals,
Two-hundred and thirty women with PCOS and normal DHEAS who failed
to ovulate with a routine protocol of CC received 200 mg of CC from day 5 to 9
and 2 mg of DEX from day 5 to 14 of the menstrual cycle. The control group
received the same protocol of CC combined with placebo.
Follicular development, hormonal status, ovulation rate, and pregnancy rate
were evaluated.
Mean follicular diameters were 18.4124±2.4314 mm and 13.8585±2.0722
mm (p<0.001) for treatment and placebo group respectively. Eighty-eight percent
of treatment and 20% of the control group had evidence of ovulation. The difference
of cumulative pregnancy rate in treatment and control groups was statistically
significant (p<0.000l).
Hormonal levels, follicular development and cumulative pregnancy rate improved
with the addition of DEX to CC in CC-resistant patients with PCOS and
normal DHEAS.This regimen is recommended before any gonadotropin therapy
or surgical intervention.
Ali Ghafouri, Omran Abbas Salehi, Seyed Ali Keshavarz, Saeed Hosseini, Abolfazl Shojaifard, Zhamak Khorgami,
Volume 26, Issue 1 (2-2012)
Abstract
Background: Today, early diagnosis of upper gastrointestinal (GI) tract malignancies and their surgical resection is becoming more feasible. One of the important side effects in upper GI tract malignancies is malnutrition which has direct relationship with postoperative complications. Nonetheless, there is no easy regimen of nutrition for these patients especially for the first week after operation. Accordingly we present a simple method for improving feeding such patients via tube jejunostomy. The aim of this study was to investigate the impact of early enteral feeding (EEF) on postoperative course after complete resection of upper gastrointestinal tract malignancy and reconstruction.
Methods: Between September 2005 to September 2008, 60 consecutive patients (22 female, 38 male) with upper GI tract malignancies who had undergone complete resection and reconstruction enrolled in this study. The patients randomly divided equally in two groups of control and EEF. Control group was treated with traditional management of nil by mouth and intravenous fluids for the first five postoperative days and then with liquids and enteral regular diet when tolerated. In EEF group the patients were fed by tube jejunostomy from 1st postoperative day and assessed for nutritional status before surgery and 5 days after surgery. Both groups were monitored on the basis of weight gain, clinical and paraclinical parameters and postoperative complications.
Results: Sixty patients were randomly divided to two equal groups. Surgical procedures were similar in two groups and no significant difference in demographic and basic nutritional status were found. On 5th postoperative day serum albumin was 4.2±0.4 g/dl in EEF and 3.6±0.3 g/dl in control group (p= 0.041). Also serum transferrin was 260.8±2.5 mg/dl and 208±1.8 mg/dl in EEF and control group respectively (p<0.001). Moreover, hospital stay was shorter in EEF group (7.7±3.1 vs. 14±2.5 days, p=0.009).There were four (13.3%) anasatomotic leakages in control group and one (3.3%) in EEF group (p=0.353). Also there was six (20%) wound infection in control group and three (10%) in EEF group (p=0.472).
Conclusion: The EEF by tube jejunostomy can be an effective method of feeding patients in postoperative days of resection of GI malignancies. Postoperative hospital stay would be shorter and the level of laboratory parameters especially serum transferrin is higher in EEF in comparison with control group. It also may reduce postoperative complications such as wound infection and enterocutaneous fistula.
Morteza Khavanin Zadeh, Saman Mohammadipour, Zahra Omrani,
Volume 29, Issue 1 (1-2015)
Abstract
Background: Arteriovenous Fistula (AVF)is the ideal method of vascular access for patients on maintenance hemodialysis (HD).Therefore it is an important part of treatment in HD.There are several observations that indicate the role of inflammation in failure of AVF.The aim of this study was to evaluate the hematologic and inflammatory biomarkers in early AVF failure.
Methods : This case-control study included 110 ESRD patients,whom were undergone AVF creation, divided in two groups. About 700 radius-cephalic AVF were created during these two years. We found 55 cases with AVF failure. In this study, we compared those 55failures with 55 functional AVF which were selected using randomized sampling from the rest of patients according to age, gender, and AVF location.Levels of serum C-reactive protein (CRP) were checked in both groups to evaluate the relation between AVF failure and CRP level before surgery.
Results : The mean±SD age of the patients was 49.7±17.28years. CRP was positive in 34 patients (61.8%)with unsuccessful fistula function,while only 4 (7.3%)of those with successful AVF had positive CRP and the resthad negative CRP.The difference between the two groups of patients was strongly significant (p<0.001). Statistically, there was not any significant difference between the average of age (p: 0.580) of patients in the control and experimental groups. However, the gender (p: 0.832) discrepancies was not meaningful between the groups.
Conclusion :AVF thrombosis is one of the main complications after AVF creation.Therefore,it is recommended to check CRP before AVF surgery to prevent possible failure of the fistulafunction.
Esmaeil Allahmoradi, Saeid Taghiloo, Versa Omrani-Nava, Saeideh Sadat Shobeiri, Mohsen Tehrani, Mohammad Ali Ebrahimzadeh, Hossein Asgarian-Omran,
Volume 32, Issue 1 (2-2018)
Abstract
Background: Portulaca oleracea, known as Purslane, is an annual growing herb with wide distribution around the world and traditionally used to manage several diseases. Different therapeutic properties as an anti-fever agent as well as anti-inflammatory and analgesic effects have been attributed to P. oleracea. The aim of this study was to investigate the effects of P. oleracea aerial extract on production of pro- and anti-inflammatory cytokines by human peripheral blood mononuclear cells (PBMCs).
Methods: Aerial parts of P. oleracea (stems and leaves) were collected and extracted by percolation using methanol. The optimal and non-cytotoxic dose of hydro-alcoholic extract for cell culture analysis was determined by MTT assay. To assess the anti-inflammatory effects of P. oleracea, PBMCs obtained from 12 normal volunteers were cultured in RPMI complete medium and co-treated with E. coli lipopolysaccharide (LPS) and P. oleracea hydro-alcoholic extract. Following 18-hour incubation, culture supernatants were harvested for measurement of secreted TNF-α, IL-6 and IL-10 by ELISA. Statistical analyses were performed using the SPSS v.20, and data analyzed by Kolmogorov-Smirnov, Mann-Whitney U, Kruskal-Wallis and post Hoc tests. P-values<0.05 were considered significant.
Results: The optimal non-cytotoxic concentration of P. oleracea aerial extract was defined as 100 μg/ml based on MTT viability assay. P. oleracea hydro-alcoholic extract significantly decreased the concentration of both pro-inflammatory cytokines TNF-α and IL-6 in LPS-stimulated PBMCs (p<0.001 and p<0.001, respectively). However, the concentration of IL-10 as an anti-inflammatory cytokine, did not show any statistically significant change (p=0.390).
Conclusion: Our findings highlighted the potential anti-inflammatory properties of P. oleracea in herbal medicine. Future analysis on different constituents of total extract may confirm its therapeutic effects as a promising anti-inflammatory compound.
Nahid Mohammadzadea, Mohammad Reza Shalbafan, Vahid Shariat, Babak Zamani, Behnam Shariati, Fateme Omrani, Mohammad Rohani,
Volume 32, Issue 1 (2-2018)
Abstract
Background: Dysregulation of serotonin system is hypothesized to play the main role in the etiology of obsessive-compulsive disorder (OCD). Transcranial sonography (TCS) is a helpful noninvasive and low-cost tool for the assessment of subcortical brain architectures, mainly basal nuclei, cerebellar central structures, and midbrain. In this study, an ultrasound assessment was performed for a sample of the patients with OCD and healthy control group to evaluate echogenicity of midbrain raphe nuclei (RN).
Methods: A total of 35 patients with OCD and 35 healthy controls of similar age and sex entered the study. Semi-structured clinical interview was performed according to the DSM IV-TR criteria to verify OCD. Echogenicity of the midbrain RN was assessed by an experienced neurologist applying TCS. The echogenicity of the 2 groups was compared using chi- square test. SPSS software (version 18, PASW) was used for statistical analysis and p-value of less than 0.05 was considered significant.
Results: In this study, 15 OCD patients (42.9%) and 11 (31.4%) controls showed decreased echogenicity of midbrain RN. Also, the results of the chi-square test showed that the midbrain RN echogenicity was not significantly lower in patients with OCD compared to the control group (p= 0.322).
Conclusion: Although decreased midbrain RN echogenicity is a characteristic of patients with major depression, it was not shown in OCD patients in this study, which can be explained by the involvement of RN projections rather that RN serotoninergic neurons.
Soheila Aminimoghaddam, Ara Omranipoor,
Volume 33, Issue 1 (2-2019)
Abstract
Ectopic pregnancy is an urgent clinical condition that represents a serious hazard to reproductive power, and thus threatens woman's health. Commonly, methotrexate is considered for early resolution of placental tissue. Despite its potential advantages such as minimizing hospitalization and quick recovery, its high skin and gastrointestinal side-effects and requiring time monitoring may limit its application. Recently, high effectiveness of the single-agent chemotherapy agents, such as Actinomycin D, has been suggested. Herein, a case of methotrexate-resistant EP that was successfully treated with Actinomycin D was described.
Morteza Khavanin Zadeh, Zahra Omrani, Roozbeh Cheraghli, Mehdi Hashemaghaee,
Volume 35, Issue 1 (1-2021)
Abstract
Background: The survival of arteriovenous fistula (AVF) remains an important problem for hemodialysis patients, accounting for 20% of all hospitalizations related to AV access problems in western countries. We designed an observational prospective cohort study on 265 AVFs and evaluated their results after 4 months of fistula creation and its relation to laboratory tests as ESR and CRP levels.
Methods: Wrist or antecubital AVFs were created for patients with End-Stage renal disease. All laboratory tests (ESR and CRP) were checked quantitatively. The patients were followed-upfor at least 4 months and failure or maturation of AVFs were recorded in a checklist.
Results: 177 (66.8%) males and 88 (33.2%) females were included. The surgeon created 161(60.8%) wrist and 98 (37%) antecubital AVFs. The mean age of patients was 53.18±17.1, ranged from 8 to 91 years old. CRP and total protein had significant differences between the two groups of failure and mature accesses (0.029 and 0.045 respectively).
Conclusion: High CRP level is recognized as a reliable predictor for the survival of AVF.
Javad Salimi, Roozbeh Cheraghali, Zahra Omrani, Pezhman Farshidmehr, Reza Afghani,
Volume 36, Issue 1 (1-2022)
Abstract
Background: Buerger's disease (thromboangiitis obliterans) may be a rare peripheral vascular disease that sometimes affects young male smokers. This study presents surgical treatment options for 315 Buerger's patients during a period of 18 years from 2002 to 2020.
Methods: In this cross-sectional study, 315 newly diagnosed Buerger patients in a period of 18 years (by Census sampling) were evaluated. Data included age, sex, cigarette smoking status, clinical presentation, the affected limb (right or left, upper or lower extremities), and the performed therapeutic procedures such as angiography of limb arteries, amputation, sympathectomy, and vascular bypass surgery, which were collected in a data sheet. Vascular reconstruction was done if there were suitable inflow and outflow arteries. Sympathectomy was performed for the patients who were unsuitable for revascularization. All analyzes were performed using SPSSV.18 software package (SPSS Inc., Chicago, IL). Data are presented as frequency, mean ± variance (SD).
Results: The mean age of patients was 42.6±9 years old, ranging from (26-75). There were 309 (98.1%) males and 6 (1.9%) females. The most common symptom was ulcer 252 (80%), and the most commonly involved arteries were the dorsal pedis (N=231; 73.4%) and posterior tibialis (N=225; 71.5%). Vascular bypass surgery, sympathectomy, and amputation were performed for patients who met surgical indications. Aortofemoral (N=9) and femoropopliteal (N=24) bypass procedures were done in 2.8% and 7.6% of patients respectively. Of nine patients who underwent aorto-femoral bypass procedure, 6 cases presented with leg claudication, 3 with an ulcer, and 3 with the Raynaud phenomenon. The digital loss rate was 9.6% (N=9) in toes and 1% (N=3) in fingers.
Conclusion: As most of the Buerger patients have multi arterial involvement, bypass surgery or sympathectomy can’t help treat these patients more than cigarette smoking or pharmaceutical therapy.
Somayyeh Shalchi Oghli, Roya Sadeghi, Ramesh Omranipour, Abbas Rahimi Foroushani, Mahnaz Ashoorkhani, Yaser Tedadi,
Volume 38, Issue 1 (1-2024)
Abstract
Background: Stress is an overwhelming feeling in patients with breast cancer (BC). However, The effect of virtual education has not been fully regulated. Hence, this study intends to compare the impact of 2 virtual education methods on perceived stress and stress coping in women with BC.
Methods: A 3-armed randomized clinical trial was conducted among 315 women with BC who were referred to the Cancer Institute in Tehran. They were randomly assigned to 3 groups: (a) Family-based, receiving family-based training package; (b) peer-support, receiving peer-support educational package; and (c) control, receiving routine hospital care. Data were collected through demographic and disease characteristics, the Perceived Stress Scale (PSS-14), and Coping Inventory for Stressful Situations (CISS-21) questionnaires before and 3 months after the intervention.
Results: The effect of the group factor after controlling the before-intervention scores in perceived stress, problem-oriented, emotion-oriented, and avoidance-oriented strategies were P < 0.0001, P = 0.015, P < 0.0001, and P = 0.111, respectively. Also, the effect of the confounding factor of BC disease stage in the dependent variables was P = 0.527, P = 0.275, P = 0.358, and P = 0.609, respectively. The effect size test showed that before the intervention, the mean scores of perceived stress, problem-oriented, emotion-oriented, and avoidance-oriented strategies were 32.00 ± 7.03, 19.36 ± 4.68, 25.10 ± 5.90, and 17.65 ± 6.64 respectively, but after the intervention showed a decrease in mean scores of perceived stress, emotion-oriented, and avoidance strategies.
Conclusion: What is vibrant in virtual family-based education is far more effective than peer support when problem-oriented coping increases. Conversely, reducing perceived stress in women with BC receiving enough information and family support should be considered.
Gamal A. Farag, Ahmed M. Omran, Sherif H. Youssif, Ramadan S. Abd Alaziz, Samir A. Nematallah, Ahmed B. Abd El Salam, Husseini F. El Boraey, Osama I. Ramadan, Tarek Zahra, Ahmed Zeina,
Volume 38, Issue 1 (1-2024)
Abstract
Background: Pectus excavatum is the most frequent congenital defect of the chest wall. Surgical treatment with modified Ravitch-type repair is recommended in patients with cosmetic dissatisfaction or considerable cardiopulmonary symptoms. We aimed to analyze the surgical, aesthetic, cardiopulmonary functions and patient satisfaction outcomes of modified Ravitch repair pre and postoperatively.
Methods: This was a prospective analysis of 13 pectus excavatum patients undergoing repair by modified Ravitch using a permanent titanium plate fixed with a screw from September 2021 to August 2023. Patients were included to relieve pressure on the heart and lungs if complaining of exercise intolerance, cosmetic impairment, shortness of breathing, chest pain, or psychological disturbance with an age range from 10 years to 30 years old. While patients who had received conservative or surgical treatment previously or patients with scoliosis, Marfan syndrome or bronchial asthma were excluded. At the 6-month postoperative visit, a postoperative satisfaction survey was conducted.
Results: The means of the age of patients (16.4 ± 2.36 years); operative duration (120 minutes); blood loss (200± 15.47 mL) and Haller index was (3.8± 0.35) preoperatively compared with less than 3.0 (2.7± 0.08 postoperatively; hospital stay (7 days). The most frequent complications were seroma in one patient (7.69%), postoperative bleeding in one patient (7.69%) and skin infection in one patient (7.69%) of patients. No recorded infection of the sternal plate or required operative re-exploration for infection. All patients were subjectively satisfied with the excellent surgical results. Exercise intolerance despite increased exercise performance was observed following surgery, including less sensation of dyspnea.
Conclusion: Modified Ravitch-type repair is a secure and reliable method for treating pectus excavatum with better relief of preoperative symptoms.
Mahmoud Abdelhamid Elhendawy, Ahmed M Omran, Sherif Hamdeno, Hazem Dahshan, Ahmed Abu_elsoud, Ahmed Salem, Mohamed Ali Abdelaziz, Khallad Sholkamy, Saber M. Abdelmaksoud,
Volume 38, Issue 1 (1-2024)
Abstract
Background: The anatomy of the eyelid changes with age. Multiple changes were observed in the eyelids and the surrounding structures including the malar region. Aging affects the appearance of eyelids and midface by the formation of tear trough deformity and malar flattening and ptosis. To define the effect of malar fat suspension on the lateral part of the infraorbital wall and orbital fat transposition in tear-trough and malar flattening and ptosis.
Methods: A retrospective study was carried out on 15 patients who had surgeries between January 2020 and January 2022. This technique combines orbital fat transposition to the medial side of the infraorbital wall and malar fat suspension to the lateral side of the infraorbital wall. The average follow-up period was 12 months. Values were compared by paired samples student or Wilcoxon signed rank test for quantitative and qualitative data respectively.
Results: There was a significant improvement in tear trough deformity, malar ptosis, and midface lift (P < 0.5). No recurrence was observed on follow-up of 12 months. One patient experienced minor postoperative complications in the form of prolonged ecchymosis for 2 months.
Conclusion: The transcutaneous lower blepharoplasty with orbital fat transposition and malar fat suspension to the lateral part of the infraorbital wall can be considered a safe and effective intervention with improved aesthetic outcome. Thus, it is recommended in patients with tear trough deformity and malar ptosis.
