Me Parsanezhad, M Raoofi, S Alborzi, Gh Omrani,
Volume 17, Issue 3 (11-2003)
Abstract
In order to evaluate the effects of short course administration of dexamethasone
(DEX) combined with clomiphene citrate (CC) in CC-resistant patients with
polycystic ovary syndrome (PCaS) and normal DHEAS, a prospective, double
blind, placebo controlled, randomized study was undertaken at referral university
hospitals,
Two-hundred and thirty women with PCOS and normal DHEAS who failed
to ovulate with a routine protocol of CC received 200 mg of CC from day 5 to 9
and 2 mg of DEX from day 5 to 14 of the menstrual cycle. The control group
received the same protocol of CC combined with placebo.
Follicular development, hormonal status, ovulation rate, and pregnancy rate
were evaluated.
Mean follicular diameters were 18.4124±2.4314 mm and 13.8585±2.0722
mm (p<0.001) for treatment and placebo group respectively. Eighty-eight percent
of treatment and 20% of the control group had evidence of ovulation. The difference
of cumulative pregnancy rate in treatment and control groups was statistically
significant (p<0.000l).
Hormonal levels, follicular development and cumulative pregnancy rate improved
with the addition of DEX to CC in CC-resistant patients with PCOS and
normal DHEAS.This regimen is recommended before any gonadotropin therapy
or surgical intervention.
Zahra Raoofi, Anahita Jalilian, Mansorah Shabani Zanjani, Seyedeh Paniz Parvar, Seyedeh Pegah Parvar,
Volume 28, Issue 1 (1-2014)
Abstract
Background: To investigate thyroid
function in preeclamptic patients in comparison with normal pregnant women.
Methods: In this analytical
cross-sectional study free Thyroxine (T4), and Thyroid Stimulating Hormone (TSH)
levels were measured in 100 preeclamptic patients and were compared with Free
T4 and TSH levels in 101 normal pregnant women in their third trimester of
pregnancy. Patients with thyroid or other systemic disorders were excluded from
this study.
Results: A significant difference in
concentration of free T4 levels (0.729 ±0.324 ng/ dl versus 0.929± 0.314 ng/dl,
p <0.001) was observed in the preeclamptic group compared with the
normotensive group, but the mean TSH level was not significantly different
(2.935±1.16 mIU/L versus 2.339±1/15 mIU/L, p = 0.170).
Conclusion: Women who develop
preeclampsia are more likely to have lower normal limits of thyroid function during
their final weeks of pregnancy.
Mehdi Jafari, Shabnam Ghasemyani, Rahim Khodayari-Zarnaq, Samira Raoofi,
Volume 35, Issue 1 (1-2021)
Abstract
Background: The Health Transformation Plan (HTP), the latest reform in Iran's health system to achieve the 3 main goals of financial protection, equity, and quality of health care, was started on May 5, 2014. This study aimed to review all available literature regarding the achievements and outcomes of this reform after 6 years of its implementation.
Methods: The 5 English databases were examined by using appropriate keywords to find documents published on the HTP between June 5, 2014, and the end of April 2020. Out of 532 recovered articles, 137 were included in the study. The study's organization was based on the Arkesy and O'Malley framework and data analysis was done using the content analysis method.
Results: The findings of the study were divided into 11 sections. Studies on the plan's impact on financial protection (22.6%), performance indicators (14.5%), and natural delivery promotion (14.5%) were the most frequent, respectively. Regarding the impact of the HTP on patient satisfaction ,performance indicators, and efficiency, mostly positive results have been obtained. However, in terms of the impact of the HTP on financial protection and informal payments, the outcomes have been different, contradictory, and sometimes negative.
Conclusion: Although the HTP has successfully achieved a number of its goals, in some of the goals, the results are not significant. Given the changing health conditions and funding constraints, it is better to consider measures to fundamentally review the HTP and executive packages.
