Mostafa Hosseini, Hamid Reza Alizadeh Otaghvar, Adnan Tizmaghz, Ghazaal Shabestanipour, Soheila Arvaneh,
Volume 29, Issue 1 (1-2015)
Abstract
Background: Fine needle aspiration (FNA) has led to a decrease in unnecessary surgeries for thyroid
nodules. This study was designed to compare diagnostic value of FNA and frozen section methods
in the follicular lesions.
Methods: This is a cross-sectional study based on the medical records of 42 patients who were referred
to surgery clinic of Rasool-e-Akram hospital in Tehran with complaint of thyroid nodules. All
FNAs were diagnosed as follicular lesions in pathologic evaluation. All the patients underwent thyroid
surgery and their frozen section results were also assessed. Finally, diagnostic value of the two
tests was compared based on final permanent histologic report.
Results: Forty two patients with follicular thyroid nodules diagnosed with FNA were included.
During the operation, using frozen sections, diagnosis of papillary carcinoma, non-papillary malignancies,
benign lesion and intermediate cytology was made in 13 (31%), 3 (7%), 25 (59.5%), 1
(2.5%) patients, respectively. Results of permanent histology showed that follicular adenoma is the
most prevalent lesion which appeared in 25 (59.5%) cases. Papillary and follicular carcinomas were
detected in 10 (23.8%) and 4 (9.5%) cases, respectively.
Conclusion: Results of the study demonstrate a 73% reduction in second surgery in patients with
follicular thyroid lesions based on intraoperative frozen section results
Mohsen Khaleghian, Adnan Tizmaghz, Majid Rezaei-Tavirani, Mohammad Amin Abbasi, Fatemeh Montazer, Ghazaal Shabestanipour, Emad Alamoutifard, Ali Tayebi, Faranak Olamaeian,
Volume 36, Issue 1 (1-2022)
Abstract
Background: We decided to compare the pathology stage of appendicitis in patients referred to Firoozabadi Medical Center before and after the official announcement of the coronavirus outbreak in Iran because we believe that people's fears of COVID-19 are keeping them away from hospitals and it likely causes them to come in later stages of the disease. Therefore, this study aims at investigating the effect of the COVID-19 pandemic on the stage of appendicitis at presentation.
Methods: In this retrospective study, histopathology records of all acute appendicitis patients who underwent an emergency appendectomy in the surgical unit in our institute between December 2019 and April 2020 were reviewed retrospectively. The study period was designed to include 2 months before and 2 months after the officially announced onset of the COVID-19 outbreak in Iran on February 20, 2020. All cases of complicated appendicitis (perforated appendicitis, phlegmonous appendix, itis or abscess) were excluded. Descriptive statistics were used to describe our study variables. Furthermore, ordinal logistic regression was used to investigate the effect of the COVID-19 pandemic and demographic variables on the stage of appendicitis at presentation. Data were analyzed using SPSS Statistics Version 22.
Results: The study was conducted on 170 clinically diagnosed acute appendicitis patients. The odds ratio for gender was equal to 0.45 (0.23, 0.86), which means that women presented at an earlier pathological stage than men (p = 0.016). Also, patients who had health insurance were 50% less likely to present in later pathological stages than those who did not (p = 0.024). The COVID-19 outback did not have a significant role in the pathological stage at presentation (p = 0.235).
Conclusion: The number of appendicitis patients was down by about 50% following the outbreak announcement in Iran. Surprisingly, we did not find any significant changes in the distribution pattern of appendicitis pathological staging after the outbreak. Being uninsured and male sex were found to have the most significant roles in delayed hospital presentation and higher pathological stages in patients with acute appendicitis.
