Showing 8 results for YAGHOOBI
F Noohi, S.h Firoozabady, F Rastgoo, A Mohebbi, F Abbaspour, M Dehghan, N Yaghoobi,
Volume 9, Issue 4 (2-1996)
Abstract
Currently, myocardial TI-201 scintigraphy is most often performed in
conjunction with exercise stress testing in patients with suspected or known CAD.
Stress thallium tests were performed for 156 patients with and without old
myocardial infarctions complaining of chest pain. All of them underwent contrast
coronary angiography. Perfusion defects were mostly manifested as reversible
defects (R). Sensitivity of visual detection was generally 93%. The anteroseptal
wall and septum showed defects more often than the other segments in patients
with LAD stenosis. The inferolateral walls showed the least defects in RCA
involvement. There was a significant difference between mean stenosis of LADs
(90± 10%) and CXs (82±11 %) (P
Aa Sayyari, F Imanzadeh, Mr Bagharpoor, Mt Arzanian, K Rafieyan, S Tahaghoghi, M Yaghoobi,
Volume 15, Issue 2 (8-2001)
Abstract
Ganglioneuroma is a very rare cause of chronic diarrhea in children. This benign
tumor usually presents with diarrhea and failure to thrive. It is necessary for
physicians to be familiar with this rare cause of chronic diarrhea. Here we present
and discuss such a case.
Mr Yaghoobi-Ershadi, Aa Akhavan, M Mohebali,
Volume 15, Issue 3 (11-2001)
Abstract
Following an epidemiological survey of zoonotic cutaneous leishmaniosis
(ZCL) in some villages of Badrood, a rural district north of the city of Natanz,
central Iran, Phlebotomus (Phlebotomus ) papatasi Scopoli were found to be naturally
infected with Leishmania (Leishmania) major zymodeme MON-26. Sandflies
were collected and dissected biweekly from rodent burrows during sandfly season,
April- October 1998. Leptomonad infection rates varied between 6.7-22.0%
during sandfly season, being greatest in September, coinciding with peak activity
of P papatasi, 2-3 months before the highest incidence of ZCL human cases in
November-December. Leptomonad infection rate was 1.1 % in 94 P papatasi
indoors.
M Mohebali, Mh Motazedian, F Parsa, H Hajjaran, Mr Yaghoobi-Ershadi,
Volume 15, Issue 4 (2-2002)
Abstract
In this study, we used Random Amplified Polymorphic DNA (RAPD) for
identification of 17 isolates of Leishmania from the skin and reticuloendothelial
system of humans, animal reservoirs (rodent and dog) and sandflies in various
parts of Iran in the last decade.
Fifteen species have been confirmed by isoenzyme characterization by the
London School of Hygiene and Tropical Medicine and Shiraz University of Medical
Sciences. In this study, strong confirmation has been observed between random
amplified polymorphic DNA with isoenzyme characterization.
Bahaadin Siroos, Zahra Ahmadinejad, Mohamad Tabaeizadeh, Mojtaba Hedayat Yaghoobi, Alireza Torabi, Majid Ghaffarpour,
Volume 28, Issue 1 (1-2014)
Abstract
Sarcoidosis is a multisystem noncaseating granulomatous disease with a propensity for lung, eye, and skin which recently have been proposed that mycobacterium tuberculosis may contribute in its pathogenesis, and rarely involves central nervous system (CNS). Despite CD4+ lymphocytopenia, sarcoidosis by itself does not increase risk of opportunistic infections other than cryptococcosis.Nonetheless, simultaneous association of CNS cryptococcosis and tuberculosis infection remains extremely rare event in immunocompetent states, and has not been reported in sarcoidosis yet. We here presented such a case ina 42 years old man, a known case of sarcoidosis with diagnostic and therapeutic difficulties were encountered in a fourteen-month-long hospitalization period.
Mahboobeh Hajiabdolbaghi, Sirous Jafari, Sedighe Mansouri, Mojtaba Hedayat Yaghoobi,
Volume 28, Issue 1 (1-2014)
Abstract
Background: HIV/AIDS patients are mainly hospitalized for HIV-related diseases and opportunistic infections. Thisstudy was performed todetermine thecauses ofhospitalization and its related factors in HIV/AIDS patients in Tehran’s Imam Khomeini Hospital during 2009-2012.
Methods: Thisstudy wasa descriptive cross-sectionalstudy . HIV patients admitted to the Imam Khomeini Hospital were included in the study through censusmethod, during the study. Demographic variables, hepatitis co-infection, CD4 count, history of receiving anti- retroviral therapy (ART), cause of admission, length of hospitalization and patient's outcome were recorded . Data were analyzed by SPSS software and by means of Chi-square and Mann Whitney U tests .
Results: Duringthe study,555HIV patientswere included in,84.9 % of whom were male, with the mean age of 36.59±8.51years and the average length of hospitalization for 16.04±18.82 days.
Opportunistic infections were the most common cause of hospitalization (46.5%) with prevalent of which was pulmonary tuberculosis being the most prevalent (37.6%).
Patientssuffering fromopportunistic infectionshadsignificantlylowerCD4countand longer hospitalizationthan theother diseases.
A significant difference was detected between patients outcome and the history of ART.
Conclusion: Low CD4 count may contribute to an increase in number and length of hospitalization in HIV/AIDS patients. Accordingly, it appears to affect outcome of their treatment and ART was accompanied by a drop in the death rate of hospitalized patients.
Iman Rezaee Azhar, Mahmood Yaghoobi, Leila Ghalich, Zahra Masoudian, Aida Shabanzadeh Pirsaraei, Peyman Yaghoobi, Mina Hamednaghsheh, Amir Mohammad Roshanaie Zadeh, Parsa Ghafari, Saba Soltani, Soraya Bozorgmehr, Motahareh Shafiei, Seyedeh Elham Mortazavi, Azam Ghaziasadi, Bahram Sharafkhanian, Hamid Akhiani, Jamshid Javidnejad, Bizhan Nomanpour, Farid Araeynejad, Seyed Mohammad Jazayeri,
Volume 36, Issue 1 (1-2022)
Abstract
Background: Objectives were to investigate aspects of the COVID-19 epidemics via testing the individuals who were referred to Aramesh Medical Laboratory in Tehran and to integrate the molecular results with epidemiological data since the beginning of the epidemic.
Methods: In this cross-sectional Study 77528 outpatients were referred to Aramesh Medical laboratory by physicians for the diagnosis of SARS-CoV-2 infection between March 2019 and May 2021. Viral acid nucleic extracted from nasal and throat specimens and subsequently amplified using Reverse Transcriptase Real-Time PCR. Laboratory data including Ct values compared with epidemic peaks of COVID-19 countrywide. Statistical Analysis was done by SPSS 21 Software.
Results: 14312 (18.46%) tested positive.36.5% of the positive cases were in the 30 to 39 years old age group. The positive result rate was significantly different based on months, ranging from 6% to 28%, compatible with four recognized epidemic peaks encompassing the end of March through the first week of April (first epidemic peak), from June to July 2020 (second epidemic peak), October until mid of November 2020 (third epidemic wave) followed by the end of April to May 2021 (until the end period of study, in the middle of 4th peak). In 37.8% of cases, the Ct value was between 21 and 28. Two separate trends were seen for Ct ≤ 25 and Ct ≤ 20 for the first and fourth epidemic peaks, respectively. There was an association between the number of total monthly positive results and total deaths in the country, especially with the second to third peaks (in the course of summer 2020) and fourth epidemic peak.
Conclusion: It might be useful to consider laboratory admission rates as an indicator for changes in the epidemic level in the country to continue the SARS-CoV-2 surveillance in accordance with public decision-makers.
Zeinab Siami, Mojtaba Hedayat Yaghoobi, Parsa Karimi,
Volume 37, Issue 1 (2-2023)
Abstract
Background: Severe and critically-ill COVID-19 patients are characterized by a severe inflammatory response. Pharmacologic inhibition of acute-phase inflammatory pathways such as IL-6 receptor inhibitor, Tocilizumab (TCZ) may improve patient outcomes in these cases. Consequently, the therapeutic benefit of TCZ was evaluated in this study.
Methods: We evaluated intravenous tocilizumab in severe and critically ill adult COVID-19 patients who met pre-defined stringent CRS criteria. A single-center, prospective, observational cohort study was carried out among consecutive adult (≥18 years of age) in-patients with COVID-19 between March 20, 2020 and March 20, 2021. In total, 354 patients were included in our study. Mortality and time to hospital discharge were compared between patients who received tocilizumab treatment (n = 177) and those who did not (n = 177).
Results: A total of 354 patients were analyzed whereas 177 patients were included in each group. In those receiving TCZ, all-cause mortality was significantly reduced, corresponding to an adjusted hazard ratio (HR) of 0.57, (95% confidence interval (CI): 0.43-0.76; P < 0.001). Furthermore, time to discharge was significantly improved in the TCZ group (HR: 1.66; 95%CI: 1.17-2.36, P = 0.004). Invasive mechanical ventilation was not statistically different among the study groups after adjusting for confounding variables (HR: 1.38; 95%CI: 0.89-2.14; P = 0.139). Dosing frequency was independent of survival status (P = 0.676).
Conclusion: The use of TCZ in ICU-hospitalized patients resulted in improved patient survival and reduced duration of hospitalization. Further studies are needed to confirm the efficacy of TCZ in severe and critical COVID-19 cases.
