Showing 4 results for Zare Mehrjardi
Jalal Vahedian Ardekani, Ali Zare Mehrjardi,
Volume 11, Issue 2 (8-1997)
Abstract
Tailgut cyst is a very rare lesion of the retrorectal space seemingly derived
from embryonic remnants of the tail gut which often causes rectal signs and
symptoms. A unique case of this lesion presenting as a subcutaneous mass lateral
to the coccyx is hereby described
Ali Zare Mehrjardi, Mehdi Massoumian,
Volume 12, Issue 4 (2-1999)
Abstract
Discrimination of regenerative cirrhotic nodules of the liver (CN) from
hepatocellular carcinoma (HCC) is sometimes difficult. We examined the utility of
AgNOR staining in this context. Fifteen cases of HCC and 25 cases of CN were
stained by AgNOR method and the mean AgNOR number for one hundred nuclei in
each case was determined. There was a significant difference between the mean
AgNOR counts in CN (6.63±4.00) and HCC (11.36±2.88) (p<0.0005).
Discriminant analysis showed that all HCC cases and over 90% of CN could be
correctly distinguished by this method. It seems that AgNOR staining is an accurate
and readily available tool for differentiating CN from HCC.
F Tirgari, Ali Zare Mehrjardi, Guity Iravanloo,
Volume 14, Issue 2 (8-2000)
Abstract
In human breast cancer, estrogen receptor (ER) status of the tumor has prognostic
and therapeutic significance. However, facilities to study ER are not widely
available to us. We postulated that if there is a correlation between histologic
grade and ER status of invasive ductal carcinoma (IDC), it may help predict the
ER status of the tumor. Of 8 4 cases of breast carcinoma referred to the Cancer
I:q.stitute of Tehran for immunohisto logic study of ER in 1995, 69 cases of IDC
that had adequate H & E stained slides were chosen. Using the Nottingham modifi.
cation of the Bloom-Richardson grading system of IDC, all cases were scored
by each of us separately. Conflicting cases were jointly reassessed until a consensus
was reached. Sections of paraffin blocks were stained for ER using the avidinbiotin
complex method and then they were assessed by a digital image analyzer.
There was an inverse relationship between ER positivity of tumors and each
of the grading parameters and the•ultimate grade that were all statistically significant
(p<0.0001). Moreover, further analysis revealed that low histologic grade
(with scores of3 or 4) had a 92.3% positive predictive value (range 62.9%-98 .2%)
for ER positivity. Similarly, histologic grade-=-in the presence of score 3 nuclei-had
an 83.9% positive predictive value (range 71.2%-91.9%) of ER negativity in tumor
cells. These findings suggest that in tumors with histologic grades at both
ends of the spectrum, ER status may reliably be predicted in a significant number
of cases.
Ali Zare Mehrjardi,
Volume 17, Issue 4 (2-2004)
Abstract
