Showing 4 results for Fna
Ghr Omrani, Py Kumar, S Tabei, M Khoddami,
Volume 8, Issue 1 (5-1994)
Abstract
377 patients with single thyroid nodule who clinically were candidates for
surgery, were selected from the patients that referred to the clinics of endocrinology
at Namazee Hospital, Shiraz Medical School. Fine needle aspiration (FNA) was
carried out without performing thyroid scan and the results were compared with
histology obtained by surgery to establish its accuracy in our center. which is an area
of endemic goiter. 72% were benign confirmed by surgery, 17% malignant(of which
two cases were colloid goiter) and II % (42 cases) were suspicious: of these 42
suspicious cases, 28.5% were follicular carcinoma and the rest were benign. In this
study sensitivity and specificity of FNA were 91 % and 97%, respectively. In
conclusion, although our area is an endemic goiter area, the accuracy of FNA is
comparable to iodine sufficient areas.
B Geramizadeh, A Azizi, Pv Kumar, Hr Forootan, A Rasekhi,
Volume 18, Issue 1 (5-2004)
Abstract
The aim of this study was to evaluate the role of fine needle aspiration cytology in
the diagnosis of abdominal and retroperitoneal masses in children on this study. In 53
cases of childhood abdominal and retroperitoneal masses within a 4 year period (1998-
2001) preoperative fine needle aspiration was done under the guide of CT scan. 2
pathologists reviewed fine needle aspiration smears. In all of the cases the gold standard
for diagnosis was the tissue specimen, which showed 37 malignant, 2 benign
neoplastic and 12 nonneoplastic diseases. This study showed that the sensitivity and
specificity of fme needle aspiration cytology for the diagnosis of malignancy and benignity
(positive or negative for malignancy) is 97.2% and 81.2% respectively. It was
100% accurate for the diagnosis of cell type in neuroblastoma-ganglioneuroblastoma,
hepatoblastoma and Wilm's tumor, 77% accurate for lymphoma and 57% for germ cell
tumors. There was no complication in any of the cases after fine needle aspiration. So
fine needle aspiration is a reliable and sensitive method for the preoperative diagnosis
of malignant pediatric abdominal and retroperitoneal masses and we recommend doing
FNA cytology as a routine method for the diagnosis of such cases.
A. Ghafouri, Sh. Attarian, M. Tavangar, N. Sedighi,
Volume 20, Issue 3 (11-2006)
Abstract
ABSTRACT
Background: Evaluation of breast masses in women under 40 years old starts with a Triple Test Score (TTS) which is composed of clinical breast examination, mammography and fine needle aspiration. Increased breast density in this age group decreases the sensitivity of mammography. So deciding whether to biopsy such nondiagnostic lesions or not is subject to challenge. Breast masses up to 2mm could be observed by ultrasonography using probes with high frequencies (10-13 MHz) with a specificity and sensitivity of more than 80%.
Methods: This study was conducted to evaluate the efficacy of ultrasonography instead of mammography in triple test scores (TTS) of nondiagnostic breast masses in women under 40 years of age and compare the results with open biopsy. To address this issue, breast masses in 100 randomly selected women under 40 were evaluated utilizing physical examination, breast ultrasonography and FNA as a modified triple test score (MTTS) which assigned score 1 for benign, score 2 for suspicious and score 3 for malignant results in each component of TTS. Summation of these three scores was assigned as MTTS. Thereafter all masses were evaluated by open biopsy.
Results: Among 100 masses in 100 women, 69 scored 3 points, 15 scored 4 points all of them were benign. Four scored 5 points 1 of them was malignant. Five scored 6 points three of them were malignant. Seven scored 7, 8, and 9 all of them were malignant.
Conclusion: The MTTS is with 100% diagnostic accuracy for malignancy when it is greater than 7 points. Masses scoring 4 points or lower are benign. Seven up to nine points may proceed to definitive therapy. Five and six points need clinical evaluation and open biopsy. The results of MTTS are similar to TTS in evaluation of breast masses in women under 40 years old and could avoid unnecessary open breast biopsy.
Mostafa Hosseini, Hamid Reza Alizadeh Otaghvar, Adnan Tizmaghz, Ghazaal Shabestanipour, Soheila Arvaneh,
Volume 29, Issue 1 (1-2015)
Abstract
Background: Fine needle aspiration (FNA) has led to a decrease in unnecessary surgeries for thyroid
nodules. This study was designed to compare diagnostic value of FNA and frozen section methods
in the follicular lesions.
Methods: This is a cross-sectional study based on the medical records of 42 patients who were referred
to surgery clinic of Rasool-e-Akram hospital in Tehran with complaint of thyroid nodules. All
FNAs were diagnosed as follicular lesions in pathologic evaluation. All the patients underwent thyroid
surgery and their frozen section results were also assessed. Finally, diagnostic value of the two
tests was compared based on final permanent histologic report.
Results: Forty two patients with follicular thyroid nodules diagnosed with FNA were included.
During the operation, using frozen sections, diagnosis of papillary carcinoma, non-papillary malignancies,
benign lesion and intermediate cytology was made in 13 (31%), 3 (7%), 25 (59.5%), 1
(2.5%) patients, respectively. Results of permanent histology showed that follicular adenoma is the
most prevalent lesion which appeared in 25 (59.5%) cases. Papillary and follicular carcinomas were
detected in 10 (23.8%) and 4 (9.5%) cases, respectively.
Conclusion: Results of the study demonstrate a 73% reduction in second surgery in patients with
follicular thyroid lesions based on intraoperative frozen section results
