Showing 3 results for Hiv Infection
Mahboobeh Hajiabdolbaghi, Sirous Jafari, Sedighe Mansouri, Mojtaba Hedayat Yaghoobi,
Volume 28, Issue 1 (1-2014)
Abstract
Background: HIV/AIDS patients are mainly hospitalized for HIV-related diseases and opportunistic infections. Thisstudy was performed todetermine thecauses ofhospitalization and its related factors in HIV/AIDS patients in Tehran’s Imam Khomeini Hospital during 2009-2012.
Methods: Thisstudy wasa descriptive cross-sectionalstudy . HIV patients admitted to the Imam Khomeini Hospital were included in the study through censusmethod, during the study. Demographic variables, hepatitis co-infection, CD4 count, history of receiving anti- retroviral therapy (ART), cause of admission, length of hospitalization and patient's outcome were recorded . Data were analyzed by SPSS software and by means of Chi-square and Mann Whitney U tests .
Results: Duringthe study,555HIV patientswere included in,84.9 % of whom were male, with the mean age of 36.59±8.51years and the average length of hospitalization for 16.04±18.82 days.
Opportunistic infections were the most common cause of hospitalization (46.5%) with prevalent of which was pulmonary tuberculosis being the most prevalent (37.6%).
Patientssuffering fromopportunistic infectionshadsignificantlylowerCD4countand longer hospitalizationthan theother diseases.
A significant difference was detected between patients outcome and the history of ART.
Conclusion: Low CD4 count may contribute to an increase in number and length of hospitalization in HIV/AIDS patients. Accordingly, it appears to affect outcome of their treatment and ART was accompanied by a drop in the death rate of hospitalized patients.
Hossein Mirzaei, Yousef Moradi, Samaneh Abbaszadeh, Naser Nasiri, Soheil Mehmandoost, Mehrdad Khezri, Fatemeh Tavakoli, Hamid Sharifi,
Volume 36, Issue 1 (1-2022)
Abstract
Background: People living with HIV (PLHIV) and those at risk of HIV are marginalized worldwide and need to reach services regularly. The COVID-19 pandemic can disrupt the HIV care continuum. This study aimed to identify the extent to which HIV-related services have been affected by the COVID-19 pandemic and how we can overcome these challenges.
Methods: In this rapid review, we systematically searched PubMed and Scopus databases, the references of studies, international agencies, and studies "cited by" feature in google scholar till May 28, 2021, without restrictions to language.
Results: Among the total of 1,121 studies, 31 of them were included in the review. The most important HIV-related services affected by the COVID-19 pandemic were; access to anti-retroviral drugs, HIV testing, periodic HIV-related testing in people living with HIV (PLHIV), pre-exposure prophylaxis, post-exposure prophylaxis, harm reduction services, psychological and counseling services. Some factors were introduced to mitigate the effects of these challenges, including increasing the resilience of health, protecting health care workers and their clients against COVID-19 through vaccination, providing HIV-related services through telehealth, and multi-month dispensing (MMD) of medicines.
Conclusion: The results of this review study showed that PLHIV had difficulty in accessing follow-up, care and treatment services during the COVID-19 pandemic. Programs such as the MMD or telemedicine can be useful in providing services to PLHIV during the pandemic.
Marjan Shakiba, Shervin Shokouhi, Fariba Alaei, Amirreza Keyvanfar, Hanieh Najafiarab, Mehrdad Yasaei,
Volume 37, Issue 1 (2-2023)
Abstract
Background: Human immunodeficiency virus (HIV) resulted in considerable morbidity and mortality. Following antiretroviral therapy (ART), the life expectancy of HIV-infected patients increased; however, they were more at risk of developing chronic diseases such as endocrinopathies. This study aimed to determine the prevalence of dysglycemia, dyslipidemia, and metabolic syndrome among patients with HIV infection.
Methods: This cross-sectional study was conducted on HIV-infected patients referring to Loghman Hakim Hospital (Tehran, Iran) between April 2020 and April 2021. We examined demographic features, medical history, and laboratory tests indicating the metabolic status of the patients. Eventually, collected data were processed using SPSS version 23.
Results: The mean age of 68 confirmed HIV patients was 39.85±10.54 years and 64.7% were male. BMI (MD = 2.57, 95% CI = [0.25, 4.88], P = 0.035), cholesterol (MD = 22.73, 95% CI = [4.70, 40.76], P = 0.014), HDL (MD = 8.54, 95% CI = [2.06, 15.02], P = 0.011), and LDL of women was significantly higher than men (MD = 22.43, 95% CI = [7.60, 37.27], P = 0.004). Additionally, 30 patients (44.1%) suffered from metabolic syndrome. The prevalence of metabolic syndrome differed significantly between men (34.1%) and women (62.50%) (P = 0.024).
Conclusion: Dysglycemia, dyslipidemia, and metabolic syndrome are common among HIV-infected patients. Thus, periodic evaluation of the patients can be advantageous in early diagnosis and timely treatment.