Ali Mirzajani, Foroozan Narooie-Noori, Rasoul Amini Vishteh, Zahra Mirsharif, Samaneh Azampour, Hoda Medhat, Seyyedeh Sara Motahar,
Volume 36, Issue 1 (1-2022)
Abstract
Background: Pregnancy-induced changes in the physiological responses during the gestational period can affect the eye. This study aimed to evaluate the effect of pregnancy on visual, refractive, vergence, and accommodative status.
Methods: In this cross-sectional study, twenty-five healthy pregnant women with a mean age of 29±3.1 were examined. All of the subjects underwent comprehensive ophthalmologic examinations, including anterior segment and fundus examinations and tonometry. Refractive error was determined in each trimester using Autokeratometer. Furthermore, near the point of convergence (NPC), best-corrected visual acuity (BCVA), and near the point of accommodation (NPA) were measured. Data analysis was performed using SPSS version 22. To compare the data during pregnancy, repeated measures analysis of variance (ANOVA) was performed.
Results: During pregnancy, in the right and left eye, spherical equivalent (SE) had a myopic shift from -0.13 to -0.35 D and +0.096 to -0.23 D, respectively (p=0.049 and p=0.020, respectively). Also, in the right and left eyes BCVA significantly decreased from -0.13 to 0.00 and -0.14 to 0.00 LogMAR, respectively (p=0.039 and p=0.045, respectively). NPA and NPC did not change statistically significantly during pregnancy (p=0.385, and p=0.801, respectively).
Conclusion: Due to the unstable hormonal status, a myopic shift and decrease in BCVA occur during pregnancy. So, any change in their spectacle prescription, fitting of contact lenses, performing refractive surgeries, etc., during this period should be postponed.
Arezoo Miraftabi, Atusa Moghadam Fard, Azadeh Yavari, Naveed Nilforushan, Samira Chaibakhsh, Navid Abolfathzadeh,
Volume 39, Issue 1 (1-2025)
Abstract
Background: There have been different reports of the retinal nerve fiber layer (RNFL) thickness in myopic and hyperopic patients in optical coherence tomography (OCT)-based studies. This study was conducted to evaluate the correlation between vascular density of the optic nerve head and refractive errors in healthy subjects using OCT-angiography (OCTA).
Methods: In a prospective interventional case series, 47 healthy subjects were enrolled consequently. The target spherical equivalent was -1.00 to +1.00, -1.00 to -6.00, and +1.00 to +4.00 in the emmetropia group (A), myopia group (B), and hyperopia group (C), respectively. The astigmatism was less than 3.00 diopters in all patients. The thickness of the retinal nerve fiber layer (RNFL), the vascular density of the optic nerve head (ONH), and the peripapillary area were measured. Statistical independent samples t-tests were used to evaluate between-group differences and the hyperopia group (group C) was considered as the reference group.
Results: Eighty-eight eyes from 47 patients were included. Twenty-five eyes (28.4%) were emmetrope, 27 eyes (30.7%) were myopic, and 36 eyes (40.9%) were hyperopic. The mean rim area was significantly lower in myopic eyes than in hyperopic eyes (1.64 vs. 1.80, P=0.039). Although the lowest mean of RNFL thickness was observed in myopic eyes, the difference between groups was not statistically significant. The nasal radial peripapillary capillaries (RPC) were significantly lower in myopic eyes versus hyperopic (49.04 vs.52.72, P=0.006). There was not any significant difference between the mean of RPC capillary inside the disc.
Conclusion: The vascular density in the RPC area was significantly lower in myopic eyes than in hyperopic and emmetropic eyes.
