BASIRI DJAHROMI S, KHAKSAR A A, VAZIRI KASHANI M, ARSID S. DISSEMINATED INFECTION DUE TO FUSARIUM SP. IN A PATIENT WI TH CHRONIC GRANULOMATOUS DISEASE. Med J Islam Repub Iran 1998; 12 (1) :93-96
URL:
http://mjiri.iums.ac.ir/article-1-1063-en.html
From the Department of Medical Mycology, Pasteur Institute of Iran
Abstract: (4879 Views)
The present report discusses disseminated fusariosis in a 15 year old boy with
chronic granulomatous disease (CGD). He was admitted to the Hazrat Rasool
Acram Hospital in November 1995, with a chronic wound in the right ankle and
buttock area. Antibacterial therapy was started, but there was no response. The
patient was still febrile. Chest x-ray revealed parahilar lesions in both lungs. Tissue
biopsy and broncho-alveolar lavage were performed and the specimens were sent
to Pasteur Institute. In both specimens, Fusarium sp. was recognized as the
pathologic agent by direct smear and culture techniques. The patient underwent
antifungal therapy receiving amphotericin B and oral ketoconazole. The result of
this treatment suggests that aggressive management of fusariosis offers the best
chance of survival. This paper reports the first case of disseminated fusariosis in
Iran.