Volume 11, Issue 3 (11-1997)                   Med J Islam Repub Iran 1997 | Back to browse issues page

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SEMNANIAN S, MOTAMEDI F. THE ROLE OF THE NORADRENERGIC SYSTEM IN ELECTRICAL STIMULATION-INDUCED ANALGESIA. Med J Islam Repub Iran 1997; 11 (3) :219-222
URL: http://mjiri.iums.ac.ir/article-1-1094-en.html
THE ROLE OF THE NORADRENERGIC SYSTEM IN ELECTRICAL STIMULATION-INDUCED ANALGESIA
S SEMNANIAN , F MOTAMEDI
From the Department of Physiology, Tarbiat Modarres University, Tehran
Abstract:   (3931 Views)
Transcutaneous electrical nerve stimulation (TENS) is an analgesia inducing method with increasing applications in clinical procedures. In this study we tried to evaluate the role of the adrenergic system and its different adrenoceptor subtypes in TENS-induced analgesia. Two types of low and high frequency electrical stimuli were used in rats through needle electrodes, inserted at the base of their tails, and different alpha and beta adrenergic agonist and antagonists were introduced to these animals. The tail immersion test was used as the analgesiometric test. Our results suggest that the noradrenergic system, through its u2 -receptor, has a significant role in electrical-induced analgesia.
Keywords: TENS, analgesia, adrenoceptors, rat tail immersion.
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Type of Study: Original Research: Basic Science in Medicine | Subject: Physiology
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