From the Ayatollah Taleghani and Ashrafi Esfahani Hospitals, Kermanshah University of Medical Sciences' School of Medicine, Kermanshah, Islamic Republic of Iran.
Abstract: (3899 Views)
The effect of sublingual nitroglycerine (TNG) on relieving pain in renal and
ureteral colic was studied in a randomized, prospective, double blind and placebo
controlled clinical trial.
One hundred out-patients between 16-60 years of age from either sex who
were admitted to the urology emergency center of Ayatollah Taleghani and
Ashrafi Esfahani hospitals were chosen for this study. They were divided into two
groups fifty-one of them were treated with TNG (0.4 mg initially and two similar
doses if necessary at 5 minute intervals) and the remaining received placebo.
The scoring of pain was performed using Lee et aI's method. Chi-square test
was used for statistical analysis of data. Although the severity of pain was reduced
one degree by TNG (p<0.07) in comparison with placebo, TNG was not effective
in the treatment of colic pain (p<0.05).