From the Department of Pharmacology, Faculty of Pharmacy, University of Karachi, Karachi-75270, Pakistan.
Abstract: (3493 Views)
The selected parts of four medicinal plants, Achillea millefolium, Hibiscus
rosasinensis, Linum usitatissimum and Pluchea lanceolata were extracted in
absolute methanol to determine their analgesic activity. Analgesic activity was
assessed on intact mice by tail flick latency via the tail immersion method. The
analgesic activities of these plant extracts were compared with acetylsalicylic acid
(300 mg/kg) which was used as the standard drug. Extracts were given orally in
doses of 300,500 and 1000 mg/kg. 0.9% saline was administered to the control
group of animals. Results showed that Linum usitatissimum and Pluchea lanceolata
possessed highly significant analgesic activity, while Achillea millefolium and
Hibiscus rosasinensis did not show any significant effects.